Search Results - "Treloar, Aislinn E."

Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression by Harris, Isaac S., Treloar, Aislinn E., Inoue, Satoshi, Sasaki, Masato, Gorrini, Chiara, Lee, Kim Chung, Yung, Ka Yi, Brenner, Dirk, Knobbe-Thomsen, Christiane B., Cox, Maureen A., Elia, Andrew, Berger, Thorsten, Cescon, David W., Adeoye, Adewunmi, Brüstle, Anne, Molyneux, Sam D., Mason, Jacqueline M., Li, Wanda Y., Yamamoto, Kazuo, Wakeham, Andrew, Berman, Hal K., Khokha, Rama, Done, Susan J., Kavanagh, Terrance J., Lam, Ching-Wan, Mak, Tak W.

“…Controversy over the role of antioxidants in cancer has persisted for decades. Here, we demonstrate that synthesis of the antioxidant glutathione (GSH), driven…”
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Noncoding somatic and inherited single-nucleotide variants converge to promote ESR1 expression in breast cancer by Bailey, Swneke D, Desai, Kinjal, Kron, Ken J, Mazrooei, Parisa, Sinnott-Armstrong, Nicholas A, Treloar, Aislinn E, Dowar, Mark, Thu, Kelsie L, Cescon, David W, Silvester, Jennifer, Yang, S Y Cindy, Wu, Xue, Pezo, Rossanna C, Haibe-Kains, Benjamin, Mak, Tak W, Bedard, Philippe L, Pugh, Trevor J, Sallari, Richard C, Lupien, Mathieu

“…Mathieu Lupien and colleagues report an enrichment of somatic mutations at the ESR1 cis -regulatory region in 7% of ESR1-positive breast cancers. They find…”
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Emergence of the Noncoding Cancer Genome: A Target of Genetic and Epigenetic Alterations by Zhou, Stanley, Treloar, Aislinn E, Lupien, Mathieu

“…The emergence of whole-genome annotation approaches is paving the way for the comprehensive annotation of the human genome across diverse cell and tissue types…”
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Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC by Grohmann, Marcus, Wiede, Florian, Dodd, Garron T., Gurzov, Esteban N., Ooi, Geraldine J., Butt, Tariq, Rasmiena, Aliki A., Kaur, Supreet, Gulati, Twishi, Goh, Pei K., Treloar, Aislinn E., Archer, Stuart, Brown, Wendy A., Muller, Mathias, Watt, Matthew J., Ohara, Osamu, McLean, Catriona A., Tiganis, Tony

“…Obesity is a major driver of cancer, especially hepatocellular carcinoma (HCC). The prevailing view is that non-alcoholic steatohepatitis (NASH) and fibrosis…”
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Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression by Harris, Isaac S., Treloar, Aislinn E., Inoue, Satoshi, Sasaki, Masato, Gorrini, Chiara, Lee, Kim Chung, Yung, Ka Yi, Brenner, Dirk, Knobbe-Thomsen, Christiane B., Cox, Maureen A., Elia, Andrew, Berger, Thorsten, Cescon, David W., Adeoye, Adewunmi, Brüstle, Anne, Molyneux, Sam D., Mason, Jacqueline M., Li, Wanda Y., Yamamoto, Kazuo, Wakeham, Andrew, Berman, Hal K., Khokha, Rama, Done, Susan J., Kavanagh, Terrance J., Lam, Ching-Wan, Mak, Tak W.

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