Search Results - "Trelles, Jorge A."

Biotransformation of halogenated nucleosides by immobilized Lactobacillus animalis 2′-N-deoxyribosyltransferase by Britos, Claudia N., Lapponi, María José, Cappa, Valeria A., Rivero, Cintia W., Trelles, Jorge A.

“…An immobilized biocatalyst with 2′-N-deoxyribosyltransferase activity (NDT) was developed from cell free extracts, resulting in a derivative with an activity…”
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Decitabine bioproduction using a biocatalyst with improved stability by adding nanocomposites by Méndez, Mariana B., Trelles, Jorge A., Rivero, Cintia W.

“…A novel IDA- La NDT derivative was able to reach the highest productivity in the biosynthesis of a well-known antitumoral agent called decitabine. However, the…”
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Dihydroxyacetone production via heterogeneous biotransformations of crude glycerol by Ripoll, Magdalena, Jackson, Erienne, Trelles, Jorge A., Betancor, Lorena

“…In this work, several immobilization strategies for Gluconobacter oxydans NBRC 14819 (Gox) were tested in the bioconversion of crude glycerol to…”
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Whole Cell Entrapment Techniques by Trelles, Jorge A, Rivero, Cintia W

“…Microbial whole cells are efficient, ecological, and low-cost catalysts that have been successfully applied in the pharmaceutical, environmental, and…”
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New developments in nucleoside analogues biosynthesis: A review by Lapponi, María J., Rivero, Cintia W., Zinni, María A., Britos, Claudia N., Trelles, Jorge A.

“…[Display omitted] •Nucleoside analogues (NAs) are commonly used as antitumoral and antiviral compounds.•Chemoenzymatic synthesis of biologically important NAs…”
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Biotransformation of cladribine by a nanostabilized extremophilic biocatalyst by Rivero, Cintia W., De Benedetti, Eliana C., Sambeth, Jorge, Trelles, Jorge A.

“…•Thermomonospora alba CECT 3324 was selected for cladribine biosynthesis.•Whole cell entrapment in a novel nanostabilized hydrogel was achieved.•Operational…”
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One-pot biosynthesis of idoxuridine using nanostabilized lactic acid bacteria by Cappa, Valeria A., Trelles, Jorge A.

“…[Display omitted] •One-pot bioprocess for idoxuridine synthesis is reported for first time.•Bio-nanocomposite is an alternative gel matrix with improved…”
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Biotransformation of cladribine by a magnetic immobilizated biocatalyst of Lactobacillus animalis by Laumann, Aldana S. Lapasset, Britos, Claudia N., Cappa, Valeria A., Rivero, Cintia W., Trelles, Jorge A.

“…A stable biocatalyst with magnetic properties based on immobilized Lactobacillus animalis ATCC 35,046 to obtain 2-chloroadenine-2′-deoxyriboside, known as…”
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Biotransformation of cladribine using a stabilized biocatalyst in calcium alginate beads by Lapponi, María J., Britos, Claudia N., Rivero, Cintia W., Trelles, Jorge A.

“…Cladribine is a nucleoside analogue widely used in the pharmaceutical industry for the treatment of several neoplasms, including hairy‐cell leukemia among…”
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Biotransformation of 5´-O-β-d-galactosyl-floxuridine by immobilized β-galactosidase from Kocuria rhizophila by Sarquiz, Andrea, Rivero, Cintia W., Britos, Claudia N., Trelles, Jorge A.

“…[Display omitted] •Kocuriarhizophila β-galactosidase was successfully stabilized in Ca-alginate.•The immobilized biocatalyst was able to…”
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Development of a high efficient biocatalyst by oriented covalent immobilization of a novel recombinant 2′-N-deoxyribosyltransferase from Lactobacillus animalis by Méndez, Mariana B., Rivero, Cintia W., López-Gallego, Fernando, Guisán, José M., Trelles, Jorge A.

“…•A novel recombinant NDT was obtained by molecular cloning from L. animalis.•L.animalis NDT was successfully stabilized in a hetero-functional support.•The…”
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Development of a nanostabilized biocatalyst using an extremophilic microorganism for ribavirin biosynthesis by De Benedetti, Eliana C., Rivero, Cintia W., Trelles, Jorge A.

“…[Display omitted] •Geobacillus kaustophilus ATCC 8005 was selected as the best strain to biosynthesize ribavirin.•Thermophilic microorganism was successfully…”
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Stabilization by multipoint covalent attachment of a biocatalyst with polygalacturonase activity used for juice clarification by Ramírez Tapias, Yuly A., Rivero, Cintia W., Gallego, Fernando López, Guisán, José M., Trelles, Jorge A.

“…•A novel immobilized PG active biocatalyst was developed for juice clarification.•Immobilized biocatalyst in glyoxyl-agarose showed high yield and…”
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Hyperstabilization of a thermophile bacterial laccase and its application for industrial dyes degradation by Gianolini, Julián E., Britos, Claudia N., Mulreedy, Carlos B., Trelles, Jorge A.

“…In the present study, a novel extracellular laccase isolated from Geobacillus stearothermophilus ATCC 10149 was entrapped in a bionanocomposite matrix…”
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Bioproduction of ribavirin by green microbial biotransformation by Rivero, Cintia W., De Benedetti, Eliana C., Lozano, Mario E., Trelles, Jorge A.

“…•Biotransformation of ribavirin was performed by E. coli ATCC 12407, reaching yields of 86%.•This mesophile microorganism was successfully stabilized in…”
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Biosynthesis of an antiviral compound using a stabilized phosphopentomutase by multipoint covalent immobilization by Rivero, Cintia W., De Benedetti, Eliana C., Gallego, Fernando López, Pessela, Benevides C., Guisán, José M., Trelles, Jorge A.

“…[Display omitted] Phosphopentomutase from E. coli ATCC 4157 has been stabilized by addition of glycerol (10%, v/v), allowing for the first time their…”
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An efficient biocatalytic system for floxuridine biosynthesis based on Lactobacillus animalis ATCC 35046 immobilized in Sr-alginate by Cappa, Valeria A., Rivero, Cintia W., Britos, Claudia N., Martinez, Luis M., Lozano, Mario E., Trelles, Jorge A.

“…•L. animalis ATCC 35046 was efficiently immobilized in Sr-alginate beads.•Sr-alginate biocatalyst was able to reach 96% of floxuridine.•Using hexane as…”
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Bioproduction of Floxuridine Using Nanostabilized Biocatalysts by Cappa, Valeria A., Rivero, Cintia W., Sambeth, Jorge E., Trelles, Jorge A.

“…Bionanocomposites employing natural polysaccharides such as alginate and nanoclays, e.g., bentonite, are a promising alternative to developing stabilized…”
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Immobilized Escherichia coli BL21 as a Catalyst for the Synthesis of Adenine and Hypoxanthine Nucleosides by Trelles, Jorge A., Bentancor, Leticia, Schoijet, Alejandra, Porro, Silvia, Lewkowicz, Elizabeth S., Sinisterra, José V., Iribarren, Adolfo M.

“…Different supports, such as alginate, agar, agarose, and polyacrylamide, were used to immobilize Escherichia coli BL 21 by entrapment techniques. The…”
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Biodegradation of vegetable residues by polygalacturonase-agar using a trickle-bed bioreactor by Ramírez-Tapias, Yuly A., Rivero, Cintia W., Giraldo-Estrada, Catalina, Britos, Claudia N., Trelles, Jorge A.

“…[Display omitted] •Heterogeneous agar-biocatalyst development with polygalacturonase activity.•Reusability up to 48 successive hydrolytic reactions demostrated…”
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