Search Results - "Treit, Peter V"
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1
The proteome landscape of the kingdoms of life
Published in Nature (London) (25-06-2020)“…Proteins carry out the vast majority of functions in all biological domains, but for technological reasons their large-scale investigation has lagged behind…”
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Plasma Proteome Profiling to detect and avoid sample‐related biases in biomarker studies
Published in EMBO molecular medicine (07-11-2019)“…Plasma and serum are rich sources of information regarding an individual's health state, and protein tests inform medical decision making. Despite major…”
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Plasma proteome profiling discovers novel proteins associated with non‐alcoholic fatty liver disease
Published in Molecular systems biology (01-03-2019)“…Non‐alcoholic fatty liver disease (NAFLD) affects 25% of the population and can progress to cirrhosis with limited treatment options. As the liver secretes…”
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Consistency across multi-omics layers in a drug-perturbed gut microbial community
Published in Molecular systems biology (12-09-2023)“…Multi-omics analyses are used in microbiome studies to understand molecular changes in microbial communities exposed to different conditions. However, it is…”
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Profiling the human intestinal environment under physiological conditions
Published in Nature (London) (18-05-2023)“…The spatiotemporal structure of the human microbiome 1 , 2 , proteome 3 and metabolome 4 , 5 reflects and determines regional intestinal physiology and may…”
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Plasma Proteomes Can Be Reidentifiable and Potentially Contain Personally Sensitive and Incidental Findings
Published in Molecular & cellular proteomics (01-01-2021)“…The goal of clinical proteomics is to identify, quantify, and characterize proteins in body fluids or tissue to assist diagnosis, prognosis, and treatment of…”
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Ethical Principles, Constraints, and Opportunities in Clinical Proteomics
Published in Molecular & cellular proteomics (01-01-2021)“…Recent advances in MS-based proteomics have vastly increased the quality and scope of biological information that can be derived from human samples. These…”
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A New Parallel High-Pressure Packing System Enables Rapid Multiplexed Production of Capillary Columns
Published in Molecular & cellular proteomics (01-01-2021)“…Reversed-phase HPLC is the most commonly applied peptide-separation technique in MS-based proteomics. Particle-packed capillary columns are predominantly used…”
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9
Generative AI entails a credit–blame asymmetry
Published in Nature machine intelligence (01-05-2023)“…Generative AI programs can produce high-quality written and visual content that may be used for good or ill. We argue that a credit–blame asymmetry arises for…”
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A Novel LC System Embeds Analytes in Pre-formed Gradients for Rapid, Ultra-robust Proteomics
Published in Molecular & cellular proteomics (01-11-2018)“…Because of low throughput and limited robustness, nano-scale liquid chromatography has been a bottleneck for advancing proteomics in biomedical research. Here,…”
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Personalised human albumin in patients with cirrhosis and ascites: design and rationale for the ALB-TRIAL - a randomised clinical biomarker validation trial
Published in BMJ open (14-02-2024)“…IntroductionHuman albumin is used in the treatment of complications of cirrhosis. However, the use of long-term human albumin administration is costly and…”
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D03 Quality control for plasma and cerebrospinal fluid samples using mass spectrometry
Published in Journal of neurology, neurosurgery and psychiatry (01-09-2018)“…Identification and quantification of disease-associated proteins in human biofluids is much needed for monitoring disease progression in HD gene expression…”
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13
Ethical principles, opportunities and constraints in clinical proteomics
Published in Molecular & cellular proteomics (04-01-2021)“…Recent advances in MS-based proteomics have vastly increased the quality and scope of biological information that can be derived from human samples. These…”
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14
Plasma proteomic data can contain personally identifiable, sensitive information and incidental findings
Published in Molecular & cellular proteomics (17-12-2020)“…The goal of clinical proteomics is to identify, quantify, and characterize proteins in body fluids or tissue to assist diagnosis, prognosis, and treatment of…”
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15
A Novel LC System Embeds Analytes in Pre-formed Gradients for Rapid, Ultra-robust Proteomics
Published in Molecular & cellular proteomics (01-11-2018)“…To further integrate mass spectrometry (MS)-based proteomics into biomedical research and especially into clinical settings, high throughput and robustness are…”
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