Search Results - "Treise, Irina"

Differential expansion of T central memory precursor and effector subsets is regulated by division speed by Kretschmer, Lorenz, Flossdorf, Michael, Mir, Jonas, Cho, Yi-Li, Plambeck, Marten, Treise, Irina, Toska, Albulena, Heinzel, Susanne, Schiemann, Matthias, Busch, Dirk H., Buchholz, Veit R.

“…While antigen-primed T cells proliferate at speeds close to the physiologic maximum of mammalian cells, T cell memory is maintained in the absence of antigen…”
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Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice by Xie, Kan, Neff, Frauke, Markert, Astrid, Rozman, Jan, Aguilar-Pimentel, Juan Antonio, Amarie, Oana Veronica, Becker, Lore, Brommage, Robert, Garrett, Lillian, Henzel, Kristin S., Hölter, Sabine M., Janik, Dirk, Lehmann, Isabelle, Moreth, Kristin, Pearson, Brandon L., Racz, Ildiko, Rathkolb, Birgit, Ryan, Devon P., Schröder, Susanne, Treise, Irina, Bekeredjian, Raffi, Busch, Dirk H., Graw, Jochen, Ehninger, Gerhard, Klingenspor, Martin, Klopstock, Thomas, Ollert, Markus, Sandholzer, Michael, Schmidt-Weber, Carsten, Weiergräber, Marco, Wolf, Eckhard, Wurst, Wolfgang, Zimmer, Andreas, Gailus-Durner, Valerie, Fuchs, Helmut, Hrabě de Angelis, Martin, Ehninger, Dan

“…Dietary restriction regimes extend lifespan in various animal models. Here we show that longevity in male C57BL/6J mice subjected to every-other-day feeding is…”
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Next generation automated traceless cell chromatography platform for GMP-compliant cell isolation and activation by Radisch, Sabine, Poltorak, Mateusz P., Wagner, Michaela, Cletiu, Vlad, Radisch, Christian, Treise, Irina, Pann, Steffi, Weigt, Alexis, Artner, Sophie, Dreher, Stefan, Fechner, Fabian, Borjan, Bojana, Fraessle, Simon P., Effenberger, Manuel, Benke, Eileen, Navratil, Gottfried, Hentschel, Norbert, Busch, Dirk H., Schmidt, Thomas, Stemberger, Christian, Germeroth, Lothar

“…Large-scale target cell isolation from patient blood preparations is one of the critical operations during drug product manufacturing for personalized cell…”
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A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes by Kollmus, Heike, Fuchs, Helmut, Lengger, Christoph, Haselimashhadi, Hamed, Bogue, Molly A., Östereicher, Manuela A., Horsch, Marion, Adler, Thure, Aguilar-Pimentel, Juan Antonio, Amarie, Oana Veronica, Becker, Lore, Beckers, Johannes, Calzada-Wack, Julia, Garrett, Lillian, Hans, Wolfgang, Hölter, Sabine M., Klein-Rodewald, Tanja, Maier, Holger, Mayer-Kuckuk, Philipp, Miller, Gregor, Moreth, Kristin, Neff, Frauke, Rathkolb, Birgit, Rácz, Ildikó, Rozman, Jan, Spielmann, Nadine, Treise, Irina, Busch, Dirk, Graw, Jochen, Klopstock, Thomas, Wolf, Eckhard, Wurst, Wolfgang, Yildirim, Ali Önder, Mason, Jeremy, Torres, Arturo, Balling, Rudi, Mehaan, Terry, Gailus-Durner, Valerie, Schughart, Klaus, Hrabě de Angelis, Martin

“…The collaborative cross (CC) is a large panel of mouse-inbred lines derived from eight founder strains (NOD/ShiLtJ, NZO/HILtJ, A/J, C57BL/6J, 129S1/SvImJ,…”
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A comprehensive phenotypic characterization of a whole-body Wdr45 knock-out mouse by Biagosch, Caroline A., Vidali, Silvia, Faerberboeck, Michael, Hensler, Svenja-Viola, Becker, Lore, Amarie, Oana V., Aguilar-Pimentel, Antonio, Garrett, Lillian, Klein-Rodewald, Tanja, Rathkolb, Birgit, Zanuttigh, Enrica, Calzada-Wack, Julia, da Silva-Buttkus, Patricia, Rozman, Jan, Treise, Irina, Fuchs, Helmut, Gailus-Durner, Valerie, de Angelis, Martin Hrabě, Janik, Dirk, Wurst, Wolfgang, Mayr, Johannes A., Klopstock, Thomas, Meitinger, Thomas, Prokisch, Holger, Iuso, Arcangela

“…Pathogenic variants in the WDR45 (OMIM: 300,526) gene on chromosome Xp11 are the genetic cause of a rare neurological disorder characterized by increased iron…”
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The Role of Fibroblast Growth Factor-Binding Protein 1 in Skin Carcinogenesis and Inflammation by Schmidt, Marcel Oliver, Garman, Khalid Ammar, Lee, Yong Gu, Zuo, Chong, Beck, Patrick James, Tan, Mingjun, Aguilar-Pimentel, Juan Antonio, Ollert, Markus, Schmidt-Weber, Carsten, Fuchs, Helmut, Gailus-Durner, Valerie, Hrabe de Angelis, Martin, Becker, Lore, Vernaleken, Alexandra, Klopstock, Thomas, Adler, Thure, Treise, Irina, Horsch, Marion, Moreth, Kristin, Brommage, Robert, Hans, Wolfgang, Östereicher, Manuela, Steinkamp, Ralph, Lengger, Christoph, Maier, Holger, Stoeger, Claudia, Leuchtenberger, Stefanie, Busch, Dirk H., Beckers, Johannes, Bekeredjian, Raffi, Garrett, Lillian, Hölter, Sabine M., Zimprich, Annemarie, Amarie, Oana, Wurst, Wolfgang, Graw, Jochen, Rozman, Jan, Calzada-Wack, Julia, da Silva-Buttkus, Patricia, Neff, Frauke, Klingenspor, Martin, Racz, Ildiko, Zimmer, Andreas, Rathkolb, Birgit, Wolf, Eckhard, Tassi, Elena, Riegel, Anna Tate, Wellstein, Anton

“…Fibroblast growth factor-binding protein 1 (FGFBP1) is a secreted chaperone that mobilizes paracrine-acting FGFs, stored in the extracellular matrix, and…”
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Defective immuno- and thymoproteasome assembly causes severe immunodeficiency by Treise, Irina, Huber, Eva M., Klein-Rodewald, Tanja, Heinemeyer, Wolfgang, Grassmann, Simon A., Basler, Michael, Adler, Thure, Rathkolb, Birgit, Helming, Laura, Andres, Christian, Klaften, Matthias, Landbrecht, Christina, Wieland, Thomas, Strom, Tim M., McCoy, Kathy D., Macpherson, Andrew J., Wolf, Eckhard, Groettrup, Marcus, Ollert, Markus, Neff, Frauke, Gailus-Durner, Valerie, Fuchs, Helmut, Hrabě de Angelis, Martin, Groll, Michael, Busch, Dirk H.

“…By N-ethyl-N-nitrosourea (ENU) mutagenesis, we generated the mutant mouse line TUB6 that is characterised by severe combined immunodeficiency (SCID) and…”
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CIP2A Promotes T-Cell Activation and Immune Response to Listeria monocytogenes Infection by Côme, Christophe, Cvrljevic, Anna, Khan, Mohd Moin, Treise, Irina, Adler, Thure, Aguilar-Pimentel, Juan Antonio, Au-Yeung, Byron, Sittig, Eleonora, Laajala, Teemu Daniel, Chen, Yiling, Oeder, Sebastian, Calzada-Wack, Julia, Horsch, Marion, Aittokallio, Tero, Busch, Dirk H, Ollert, Markus W, Neff, Frauke, Beckers, Johannes, Gailus-Durner, Valerie, Fuchs, Helmut, Hrabě de Angelis, Martin, Chen, Zhi, Lahesmaa, Riitta, Westermarck, Jukka

“…The oncoprotein Cancerous Inhibitor of Protein Phosphatase 2A (CIP2A) is overexpressed in most malignancies and is an obvious candidate target protein for…”
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In vivo functional requirement of the mouse Ifitm1 gene for germ cell development, interferon mediated immune response and somitogenesis by Klymiuk, Ingeborg, Kenner, Lukas, Adler, Thure, Busch, Dirk H, Boersma, Auke, Irmler, Martin, Fridrich, Barbara, Gailus-Durner, Valérie, Fuchs, Helmut, Leitner, Nicole, Müller, Mathias, Kühn, Ralf, Schlederer, Michaela, Treise, Irina, de Angelis, Martin Hrabě, Beckers, Johannes

“…The mammalian Interferon induced transmembrane protein 1 (Ifitm1) gene was originally identified as a member of a gene family highly inducible by type I and…”
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The endocytic adaptor Eps15 controls marginal zone B cell numbers by Pozzi, Benedetta, Amodio, Stefania, Lucano, Caterina, Sciullo, Anna, Ronzoni, Simona, Castelletti, Daniela, Adler, Thure, Treise, Irina, Betsholtz, Ingrid Holmberg, Rathkolb, Birgit, Busch, Dirk H, Wolf, Eckhard, Fuchs, Helmut, Gailus-Durner, Valérie, de Angelis, Martin Hrabě, Betsholtz, Christer, Casola, Stefano, Di Fiore, Pier Paolo, Offenhäuser, Nina

“…Eps15 is an endocytic adaptor protein involved in clathrin and non-clathrin mediated endocytosis. In Caenorhabditis elegans and Drosophila melanogaster lack of…”
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Correction: The Endocytic Adaptor Eps15 Controls Marginal Zone B Cell Numbers by Pozzi, Benedetta, Amodio, Stefania, Lucano, Caterina, Sciullo, Anna, Ronzoni, Simona, Castelletti, Daniela, Adler, Thure, Treise, Irina, Betsholtz, Ingrid Holmberg, Rathkolb, Birgit, Busch, Dirk H., Wolf, Eckhard, Fuchs, Helmut, Gailus-Durner, Valérie, de Angelis, Martin Hrabě, Betsholtz, Christer, Casola, Stefano, Di Fiore, Pier Paolo, Offenhäuser, Nina

“…The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. (2013) Correction: The Endocytic…”
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Longitudinal Frequencies of Blood Leukocyte Subpopulations Differ between NOD and NOR Mice but Do Not Predict Diabetes in NOD Mice by Bonifacio, Ezio, Ziegler, Anette-Gabriele, Adler, Kerstin, Hrabě de Angelis, Martin, Busch, Dirk H., Adler, Thure, Foertsch, Katharina, Treise, Irina, Köhler, Meike, Telieps, Tanja, Verschoor, Admar

“…Immune phenotyping provides insight into disease pathogenesis and prognostic markers. Trajectories from age of 4 to 36 weeks were modeled for insulin…”
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Comparative Phenotyping of Mice Reveals Canonical and Noncanonical Physiological Functions of TRα and TRβ by Hönes, Georg Sebastian, Geist, Daniela, Wenzek, Christina, Pfluger, Paul Thomas, Müller, Timo Dirk, Aguilar-Pimentel, Juan Antonio, Amarie, Oana Veronica, Becker, Lore, Dragano, Natalia, Garrett, Lillian, Hölter, Sabine Maria, Rathkolb, Birgit, Rozman, Jan, Spielmann, Nadine, Treise, Irina, Wolf, Eckhard, Wurst, Wolfgang, Fuchs, Helmut, Gailus-Durner, Valerie, Hrabe de Angelis, Martin, Führer, Dagmar, Moeller, Lars Christian

“…Abstract Thyroid hormone (TH) effects are mediated through TH receptors (TRs), TRα1, TRβ1, and TRβ2. The TRs bind to the DNA and regulate expression of TH…”
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Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic by Fuchs, Helmut, Aguilar-Pimentel, Juan Antonio, Amarie, Oana V., Becker, Lore, Calzada-Wack, Julia, Cho, Yi-Li, Garrett, Lillian, Hölter, Sabine M., Irmler, Martin, Kistler, Martin, Kraiger, Markus, Mayer-Kuckuk, Philipp, Moreth, Kristin, Rathkolb, Birgit, Rozman, Jan, da Silva Buttkus, Patricia, Treise, Irina, Zimprich, Annemarie, Gampe, Kristine, Hutterer, Christine, Stöger, Claudia, Leuchtenberger, Stefanie, Maier, Holger, Miller, Manuel, Scheideler, Angelika, Wu, Moya, Beckers, Johannes, Bekeredjian, Raffi, Brielmeier, Markus, Busch, Dirk H., Klingenspor, Martin, Klopstock, Thomas, Ollert, Markus, Schmidt-Weber, Carsten, Stöger, Tobias, Wolf, Eckhard, Wurst, Wolfgang, Yildirim, Ali Önder, Zimmer, Andreas, Gailus-Durner, Valérie, Hrabě de Angelis, Martin

“…Since decades, model organisms have provided an important approach for understanding the mechanistic basis of human diseases. The German Mouse Clinic (GMC) was…”
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In-depth phenotyping reveals common and novel disease symptoms in a hemizygous knock-in mouse model (Mut-ko/ki) of mut-type methylmalonic aciduria by Lucienne, Marie, Aguilar-Pimentel, Juan Antonio, Amarie, Oana V., Becker, Lore, Calzada-Wack, Julia, da Silva-Buttkus, Patricia, Garrett, Lillian, Hölter, Sabine M., Mayer-Kuckuk, Philipp, Rathkolb, Birgit, Rozman, Jan, Spielmann, Nadine, Treise, Irina, Busch, Dirk H., Klopstock, Thomas, Schmidt-Weber, Carsten, Wolf, Eckhard, Wurst, Wolfgang, Forny, Merima, Mathis, Déborah, Fingerhut, Ralph, Froese, D. Sean, Gailus-Durner, Valerie, Fuchs, Helmut, de Angelis, Martin Hrabě, Baumgartner, Matthias R.

“…Isolated methylmalonic aciduria (MMAuria) is primarily caused by deficiency of methylmalonyl-CoA mutase (MMUT or MUT). Biochemically, MUT deficiency results in…”
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The heterozygous R155C VCP mutation: Toxic in humans! Harmless in mice? by Clemen, Christoph S., Winter, Lilli, Strucksberg, Karl-Heinz, Berwanger, Carolin, Türk, Matthias, Kornblum, Cornelia, Florin, Alexandra, Aguilar-Pimentel, Juan Antonio, Amarie, Oana Veronica, Becker, Lore, Garrett, Lillian, Hans, Wolfgang, Moreth, Kristin, Neff, Frauke, Pingen, Laura, Rathkolb, Birgit, Rácz, Ildikó, Rozman, Jan, Treise, Irina, Fuchs, Helmut, Gailus-Durner, Valerie, de Angelis, Martin Hrabe, Vorgerd, Matthias, Eichinger, Ludwig, Schröder, Rolf

“…Heterozygous missense mutations in the human VCP gene cause inclusion body myopathy associated with Paget disease of bone and fronto-temporal dementia (IBMPFD)…”
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Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia by Vetrivel, Sharmilee, Tiso, Natascia, Kügler, Andrea, Irmler, Martin, Horsch, Marion, Beckers, Johannes, Hladik, Daniela, Giesert, Florian, Gailus-Durner, Valerie, Fuchs, Helmut, Sabrautzki, Sibylle, Hrabě de Angelis, Martin, Graw, Jochen

“…During an ENU (N-ethyl-N-nitrosourea) mutagenesis screen, we observed a dominant small-eye mutant mouse with viable homozygotes. A corresponding mutant line…”
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Streptozotocin-induced β-cell damage, high fat diet, and metformin administration regulate Hes3 expression in the adult mouse brain by Nikolakopoulou, Polyxeni, Chatzigeorgiou, Antonios, Kourtzelis, Ioannis, Toutouna, Louiza, Masjkur, Jimmy, Arps-Forker, Carina, Poser, Steven W., Rozman, Jan, Rathkolb, Birgit, Aguilar-Pimentel, Juan Antonio, Wolf, Eckhard, Klingenspor, Martin, Ollert, Markus, Schmidt-Weber, Carsten, Fuchs, Helmut, Gailus-Durner, Valerie, Hrabe de Angelis, Martin, Tsata, Vasiliki, Monasor, Laura Sebastian, Troullinaki, Maria, Witt, Anke, Anastasiou, Vivian, Chrousos, George, Yi, Chun-Xia, García-Cáceres, Cristina, Tschöp, Matthias H., Bornstein, Stefan R., Androutsellis-Theotokis, Andreas

“…Diabetes mellitus is a group of disorders characterized by prolonged high levels of circulating blood glucose. Type 1 diabetes is caused by decreased insulin…”
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Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema by Egaña, Isabel, Kaito, Hiroshi, Nitzsche, Anja, Becker, Lore, Ballester-Lopez, Carolina, Niaudet, Colin, Petkova, Milena, Liu, Wei, Vanlandewijck, Michael, Vernaleken, Alexandra, Klopstock, Thomas, Fuchs, Helmut, Gailus-Durner, Valerie, Hrabe de Angelis, Martin, Rask-Andersen, Helge, Johansson, Henrik J., Lehtiö, Janne, He, Liqun, Yildirim, Ali Ö., Hellström, Mats

“…Paladin ( Pald1 , mKIAA1274 or x99384) was identified in screens for vascular-specific genes and is a putative phosphatase. Paladin has also been proposed to…”
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Innovations in phenotyping of mouse models in the German Mouse Clinic by Fuchs, Helmut, Gailus-Durner, Valérie, Neschen, Susanne, Adler, Thure, Afonso, Luciana Caminha, Aguilar-Pimentel, Juan Antonio, Becker, Lore, Bohla, Alexander, Calzada-Wack, Julia, Cohrs, Christian, Dewert, Anna, Fridrich, Barbara, Garrett, Lillian, Glasl, Lisa, Götz, Alexander, Hans, Wolfgang, Hölter, Sabine M, Horsch, Marion, Hurt, Anja, Janas, Eva, Janik, Dirk, Kahle, Melanie, Kistler, Martin, Klein-Rodewald, Tanja, Lengger, Christoph, Ludwig, Tonia, Maier, Holger, Marschall, Susan, Micklich, Kateryna, Möller, Gabriele, Naton, Beatrix, Prehn, Cornelia, Puk, Oliver, Rácz, Ildikó, Räß, Michael, Rathkolb, Birgit, Rozman, Jan, Scheerer, Markus, Schiller, Evelyn, Schrewe, Anja, Steinkamp, Ralph, Stöger, Claudia, Sun, Minxuan, Szymczak, Wilfried, Treise, Irina, Vargas Panesso, Ingrid Liliana, Vernaleken, Alexandra M, Willershäuser, Monja, Wolff-Muscate, Annemarie, Zeh, Ramona, Adamski, Jerzy, Beckers, Johannes, Bekeredjian, Raffi, Busch, Dirk H, Eickelberg, Oliver, Favor, Jack, Graw, Jochen, Höfler, Heinz, Höschen, Christoph, Katus, Hugo, Klingenspor, Martin, Klopstock, Thomas, Neff, Frauke, Ollert, Markus, Schulz, Holger, Stöger, Tobias, Wolf, Eckhard, Wurst, Wolfgang, Yildirim, Ali Önder, Zimmer, Andreas, Hrabě de Angelis, Martin

“…Under the label of the German Mouse Clinic (GMC), a concept has been developed and implemented that allows the better understanding of human diseases on the…”
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