Search Results - "Treinys, Rimantas"
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1
Loss-of-activity-mutation in the cardiac chloride-bicarbonate exchanger AE3 causes short QT syndrome
Published in Nature communications (22-11-2017)“…Patients with short QT syndrome (SQTS) may present with syncope, ventricular fibrillation or sudden cardiac death. Six SQTS susceptibility genes, encoding…”
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2
Metabolic Inhibition Induces Transient Increase of L-type Ca2+ Current in Human and Rat Cardiac Myocytes
Published in International journal of molecular sciences (26-03-2019)“…Metabolic inhibition is a common condition observed during ischemic heart disease and heart failure. It is usually accompanied by a reduction in L-type Ca2+…”
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3
Metabolic inhibition reduces cardiac L-type Ca2+ channel current due to acidification caused by ATP hydrolysis
Published in PloS one (2017)“…Metabolic stress evoked by myocardial ischemia leads to impairment of cardiac excitation and contractility. We studied the mechanisms by which metabolic…”
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4
Optical mapping of the pig heart in situ under artificial blood circulation
Published in Scientific reports (22-05-2020)“…The emergence of optical imaging has revolutionized the investigation of cardiac electrical activity and associated disorders in various cardiac pathologies…”
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5
Spectral characteristics of voltage-sensitive indocyanine green fluorescence in the heart
Published in Scientific reports (11-08-2017)“…Indocyanine green (ICG) fluorescent dye has been approved by the FDA for use in medical diagnostics. Recently, we demonstrated that ICG dye has…”
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6
Evaluation of the Cardiac Electrophysiological and Haemodynamic Effects of Elsholtzia ciliata Essential Oil on Swine
Published in Pharmaceuticals (Basel, Switzerland) (10-08-2022)“…The demand for the development of novel medicines with few side effects and no proarrhythmic properties is increasing. Extensive research on herbal extracts…”
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7
R-type calcium channels are crucial for semaphorin 3A-induced DRG axon growth cone collapse
Published in PloS one (17-07-2014)“…Semaphorin 3A (Sema3A) is a secreted protein involved in axon path-finding during nervous system development. Calcium signaling plays an important role during…”
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8
Differences in the control of basal L-type Ca2+ current by the cyclic AMP signaling cascade in frog, rat, and human cardiac myocytes
Published in The journal of physiological sciences (01-07-2016)“…β-adrenergic receptors (β-ARs) mediate the positive inotropic effects of catecholamines by cAMP-dependent phosphorylation of the L-type Ca 2+ channels (LTCCs),…”
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9
Acute and Sub-Chronic Intraperitoneal Toxicity Studies of the Elsholtzia ciliata Herbal Extract in Balb/c Mice
Published in Pharmaceutics (03-10-2023)“…Elsholtzia ciliata essential oil (E. ciliata) has been reported to have an impact on the cardiovascular system. However, its toxicity remains unknown…”
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10
Mechanism of Action Potential Prolongation During Metabolic Inhibition in the Whole Rabbit Heart
Published in Frontiers in physiology (09-08-2018)“…Myocardial ischemia is associated with significant changes in action potential (AP) duration, which has a biphasic response to metabolic inhibition. Here, we…”
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11
Evaluation of excitation propagation in the rabbit heart: optical mapping and transmural microelectrode recordings
Published in PloS one (16-04-2015)“…Because of the optical features of heart tissue, optical and electrical action potentials are only moderately associated, especially when near-infrared dyes…”
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12
Antiarrhythmic Properties of Elsholtzia ciliata Essential Oil on Electrical Activity of the Isolated Rabbit Heart and Preferential Inhibition of Sodium Conductance
Published in Biomolecules (Basel, Switzerland) (23-06-2020)“…essential oil ( ) has been developed in Lithuania and internationally patented as exerting antiarrhythmic properties. Here we demonstrate the pharmacological…”
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13
Exogenous connexin43-expressing autologous skeletal myoblasts ameliorate mechanical function and electrical activity of the rabbit heart after experimental infarction
Published in International journal of experimental pathology (01-02-2015)“…Summary Acute myocardial infarction is one of the major causes of mortality worldwide. For regeneration of the rabbit heart after experimentally induced…”
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14
Metabolic inhibition reduces cardiac L-type Ca.sup.2+ channel current due to acidification caused by ATP hydrolysis
Published in PloS one (31-08-2017)“…Metabolic stress evoked by myocardial ischemia leads to impairment of cardiac excitation and contractility. We studied the mechanisms by which metabolic…”
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15
Alteration of Action Potential during Early Ischemia in the Heart
Published in Biophysical journal (03-02-2017)Get full text
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16
Voltage-Sensitive ICG Fluorescence Imaging
Published in Biophysical journal (03-02-2017)Get full text
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17
Evaluation of the Cardiac Electrophysiological and Haemodynamic Effects of IElsholtzia ciliata/I Essential Oil on Swine
Published in Pharmaceuticals (Basel, Switzerland) (01-08-2022)“…The demand for the development of novel medicines with few side effects and no proarrhythmic properties is increasing. Extensive research on herbal extracts…”
Get full text
Journal Article -
18
Acute and Sub-Chronic Intraperitoneal Toxicity Studies of the IElsholtzia ciliata/I Herbal Extract in Balb/c Mice
Published in Pharmaceutics (01-10-2023)“…Elsholtzia ciliata essential oil (E. ciliata) has been reported to have an impact on the cardiovascular system. However, its toxicity remains unknown…”
Get full text
Journal Article -
19
DRG Axon Elongation and Growth Cone Collapse Rate Induced by Sema3A are Differently Dependent on NGF Concentration
Published in Cellular and molecular neurobiology (01-03-2014)“…Regeneration of embryonic and adult dorsal root ganglion (DRG) sensory axons is highly impeded when they encounter neuronal growth cone-collapsing factor…”
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20
Metabolic Inhibition Induces Transient Increase of L-type Ca 2+ Current in Human and Rat Cardiac Myocytes
Published in International journal of molecular sciences (26-03-2019)“…Metabolic inhibition is a common condition observed during ischemic heart disease and heart failure. It is usually accompanied by a reduction in L-type Ca…”
Get full text
Journal Article