Search Results - "Tree, David R.P."

Mathematical modeling of planar cell polarity to understand domineering nonautonomy by Amonlirdviman, K, Khare, N.A, Tree, D.R.P, Chen, W.S, Axelrod, J.D, Tomlin, C.J

“…Planar cell polarity (PCP) signaling generates subcellular asymmetry along an axis orthogonal to the epithelial apical-basal axis. Through a poorly understood…”
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Prickle Mediates Feedback Amplification to Generate Asymmetric Planar Cell Polarity Signaling by Tree, David R.P., Shulman, Joshua M., Rousset, Raphaël, Scott, Matthew P., Gubb, David, Axelrod, Jeffrey D.

“…Planar cell polarity signaling in Drosophila requires the receptor Frizzled and the cytoplasmic proteins Dishevelled and Prickle. From initial, symmetric…”
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A three-tiered mechanism for regulation of planar cell polarity by Tree, David R.P, Ma, Dali, Axelrod, Jeffrey D

“…Some epithelial cells are polarized along an axis orthogonal to their apical–basal axes. Recent studies in Drosophila lead to the view that three classes of…”
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Towards a Drosophila model of Hutchinson-Gilford progeria syndrome by Beard, Gemma S, Bridger, Joanna M, Kill, Ian R, Tree, David R P

“…The laminopathy Hutchinson-Gilford progeria syndrome (HGPS) is caused by the mutant lamin A protein progerin and leads to premature aging of affected children…”
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