Search Results - "Tredicine, Maria"
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S100B Protein as a Therapeutic Target in Multiple Sclerosis: The S100B Inhibitor Arundic Acid Protects from Chronic Experimental Autoimmune Encephalomyelitis
Published in International journal of molecular sciences (17-12-2021)“…S100B is an astrocytic protein behaving at high concentration as a damage-associated molecular pattern molecule. A direct correlation between the increased…”
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Reticulocytes in donor blood units enhance red blood cell alloimmunization
Published in Haematologica (Roma) (01-10-2023)“…Although red blood cell (RBC) transfusions save lives, some patients develop clinically-significant alloantibodies against donor blood group antigens, which…”
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Fc γ RIV is required for IgG2c mediated enhancement of RBC alloimmunization
Published in Frontiers in immunology (13-09-2022)“…Passive immunization with anti-D can prevent maternal alloimmunization to RhD thereby preventing hemolytic disease of the fetus and newborn. Unexpectedly,…”
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Regionally restricted modulation of Sam68 expression and Arhgef9 alternative splicing in the hippocampus of a murine model of multiple sclerosis
Published in Frontiers in molecular neuroscience (12-01-2023)“…Multiple sclerosis (MS) and its preclinical models are characterized by marked changes in neuroplasticity, including excitatory/inhibitory imbalance and…”
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Immunopathology of SARS-CoV-2 Infection: A Focus on T Regulatory and B Cell Responses in Children Compared with Adults
Published in Children (Basel) (07-05-2022)“…While the clinical impact of COVID-19 on adults has been massive, the majority of children develop pauci-symptomatic or even asymptomatic infection and only a…”
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Haemophilus parasuis (Glaesserella parasuis) as a Potential Driver of Molecular Mimicry and Inflammation in Rheumatoid Arthritis
Published in Frontiers in medicine (17-08-2021)“…Background: Haemophilus parasuis ( Hps ; now Glaesserella parasuis ) is an infectious agent that causes severe arthritis in swines and shares sequence…”
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A TLR/CD44 axis regulates T cell trafficking in experimental and human multiple sclerosis
Published in iScience (18-02-2022)“…In the pathogenesis of autoimmune disorders, the modulation of leukocytes′ trafficking plays a central role, still poorly understood. Here, we focused on the…”
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Mitigation of checkpoint inhibitor–induced autoimmune hemolytic anemia through modulation of purinergic signaling
Published in Blood (10-10-2024)“…•Discovery of a novel CD39+ T-cell population that predicts AIHA onset due to ICPi therapy.•This study demonstrates that apyrase acts as a novel therapeutic,…”
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Liposome-based nanoparticles impact on regulatory and effector phenotypes of macrophages and T cells in multiple Sclerosis patients
Published in Biomaterials (01-01-2023)“…Current available treatments of Multiple Sclerosis (MS) reduce neuroinflammation acting on different targets on the immune system, but potentially lead to…”
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Reticulocytes Are an Unappreciated Risk Factor for RBC Alloimmunization at the Donor and Recipient Levels
Published in Blood (15-11-2022)Get full text
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Retention of functional mitochondria in mature red blood cells from patients with sickle cell disease
Published in British journal of haematology (01-08-2022)“…Summary Sickle cell disease (SCD) is an inherited blood disorder characterized by sickled red blood cells (RBCs), which are more sensitive to haemolysis and…”
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Translational Research in the Era of Precision Medicine: Where We Are and Where We Will Go
Published in Journal of personalized medicine (18-03-2021)“…The advent of Precision Medicine has globally revolutionized the approach of translational research suggesting a patient-centric vision with therapeutic…”
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Past and Future of the Molecular Characterization of the T Cell Repertoire: Some Highlights of Eli Sercarz's Contributions
Published in Critical reviews in immunology (2020)“…The contribution of Eli E. Sercarz to immunology and immunopathology has been remarkable and achieved many milestones in the understanding of the processes of…”
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Critical Reviews in Immunology
Published in Critical reviews in immunology (2020)“…The contribution of Eli E. Sercarz to immunology and immunopathology has been remarkable and achieved many milestones in the understanding of the processes of…”
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Retention of functional mitochondria in mature RBCs from patients with SCD
Published in British journal of haematology (07-06-2022)“…Sickle cell disease (SCD) is an inherited blood disorder characterized by sickled red blood cells (RBCs), which are more sensitive to hemolysis and can…”
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Recovering or Persisting: The Immunopathological Features of SARS-CoV-2 Infection in Children
Published in Journal of clinical medicine (27-07-2022)“…Background. The profile of cellular immunological responses of children across the spectrum of COVID-19, ranging from acute SARS-CoV-2 infection to full…”
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