Search Results - "Trede, N.S."

Notch signaling expands a pre-malignant pool of T-cell acute lymphoblastic leukemia clones without affecting leukemia-propagating cell frequency by Blackburn, J S, Liu, S, Raiser, D M, Martinez, S A, Feng, H, Meeker, N D, Gentry, J, Neuberg, D, Look, A T, Ramaswamy, S, Bernards, A, Trede, N S, Langenau, D M

“…NOTCH1 pathway activation contributes to the pathogenesis of over 60% of T-cell acute lymphoblastic leukemia (T-ALL). While Notch is thought to exert the…”
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TREATMENT OF RELAPSED/REFRACTORY AGGRESSIVE NON‐HODGKIN LYMPHOMA (NHL) WITH LISOCABTAGENE MARALEUCEL IN THE OUTPATIENT SETTING: RESULTS FROM TWO PHASE 2 TRIALS by Sehgal, A., Godwin, J.E., Maris, M.B., Hildebrandt, G.C., Trede, N.S., Kostic, A., Wang, L., Lymp, J., Bachier, C.R.

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Shared acquired genomic changes in zebrafish and human T-ALL by Rudner, L A, Brown, K H, Dobrinski, K P, Bradley, D F, Garcia, M I, Smith, A C H, Downie, J M, Meeker, N D, Look, A T, Downing, J R, Gutierrez, A, Mullighan, C G, Schiffman, J D, Lee, C, Trede, N S, Frazer, J K

“…T-cell acute lymphoblastic leukemia (T-ALL) is a challenging clinical entity with high rates of induction failure and relapse. To discover the genetic changes…”
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Heritable T-cell malignancy models established in a zebrafish phenotypic screen by Frazer, J K, Meeker, N D, Rudner, L, Bradley, D F, Smith, A C H, Demarest, B, Joshi, D, Locke, E E, Hutchinson, S A, Tripp, S, Perkins, S L, Trede, N S

“…T-cell neoplasias are common in pediatric oncology, and include acute lymphoblastic leukemia (T-ALL) and lymphoblastic lymphoma (T-LBL). These cancers have…”
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