Search Results - "Treco, Douglas"

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  1. 1

    Template-directed synthesis of a genetic polymer in a model protocell by Szostak, Jack W, Mansy, Sheref S, Schrum, Jason P, Krishnamurthy, Mathangi, Tobé, Sylvia, Treco, Douglas A

    Published in Nature (03-07-2008)
    “…Contemporary phospholipid-based cell membranes are formidable barriers to the uptake of polar and charged molecules ranging from metal ions to complex…”
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    Effect of Stalling after Mismatches on the Error Catastrophe in Nonenzymatic Nucleic Acid Replication by Rajamani, Sudha, Ichida, Justin K, Antal, Tibor, Treco, Douglas A, Leu, Kevin, Nowak, Martin A, Szostak, Jack W, Chen, Irene A

    Published in Journal of the American Chemical Society (28-04-2010)
    “…The frequency of errors during genome replication limits the amount of functionally important information that can be passed on from generation to generation…”
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    Nonviral Transfer of the Gene Encoding Coagulation Factor VIII in Patients with Severe Hemophilia A by Roth, David A, Tawa, Nicholas E, O'Brien, Joanne M, Treco, Douglas A, Selden, Richard F

    Published in The New England journal of medicine (07-06-2001)
    “…In some of the recipients, the plasma levels of factor VIII activity rose and bleeding diminished for up to 10 months. Hemophilia A, an X-linked hemorrhagic…”
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    Growth and manipulation of yeast by Treco, Douglas A, Winston, Fred

    “…Yeast cultures can be grown, maintained, and stored in liquid media or on agar plates using techniques similar to those for bacterial cultures. This unit…”
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    An initiation site for meiotic gene conversion in the yeast Saccharomyces cerevisiae by Nicolas, Alain, Treco, Douglas, Schultes, Neil P, Szostak, Jack W

    Published in Nature (London) (02-03-1989)
    “…An initiation site for meiotic gene conversion has been identified in the promoter region of the ARG4 gene of Saccharomyces cerevisiae. The chromosome on which…”
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    Preclinical Evaluation of RA101495, a Potent Cyclic Peptide Inhibitor of C5 for the Treatment of Paroxysmal Nocturnal Hemoglobinuria by Ricardo, Alonso, Arata, Michelle, DeMarco, Steven, Dhamnaskar, Ketki, Hammer, Robert, Fridkis-Hareli, Masha, Rajagopal, Vaishnavi, Seyb, Kathleen, Tang, Guo-Qing, Tobe, Sylvia, Treco, Douglas

    Published in Blood (03-12-2015)
    “…Regulation of the terminal phase of the complement component pathway is a clinically validated approach for the therapeutic treatment of complement disorders…”
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  8. 8

    Development of RA101348, a Potent Cyclic Peptide Inhibitor of C5 for Complement-Mediated Diseases by Ricardo, Alonso, Arata, Michelle, DeMarco, Steven J, Dhamnaskar, Ketki, Hammer, Robert, Josephson, Kristopher, Seyb, Kathleen, Tobe, Sylvia, Wang, Zhaolin, Zheng, Hong, Treco, Douglas

    Published in Blood (06-12-2014)
    “…The involvement of complement in the pathogenesis of serious, life-threatening diseases underscores the importance in developing therapeutics to intervene in…”
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    Extensive 3'-overhanging, single-stranded DNA associated with the meiosis-specific double-strand breaks at the ARG4 recombination initiation site by Sun, H, Treco, D, Szostak, J W

    Published in Cell (22-03-1991)
    “…Meiosis-specific double-strand breaks occur at the initiation site for meiotic gene conversion in the yeast ARG4 gene. Here we show that the break fragments…”
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    Preparation of yeast media by Treco, D A, Lundblad, V

    “…Preparation of sterile media of consistently high quality is essential for the genetic manipulation of yeast. Recipes for media needed in the protocols in this…”
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  12. 12

    Double-strand breaks at an initiation site for meiotic gene conversion by Sun, H, Treco, D, Schultes, N P, Szostak, J W

    Published in Nature (London) (02-03-1989)
    “…It has been proposed that the initiation of meiotic recombination involves either single-strand or double-strand breaks in DNA. It is difficult to distinguish…”
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  13. 13

    Growth and manipulation of yeast by Treco, D A, Winston, F

    “…Preparation of sterile media of consistently high quality is essential for the genetic manipulation of yeast. Recipes for media needed in the protocols in this…”
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    Long-Term Production and Delivery of Human Growth Hormone In vivo by Heartlein, Michael W., Roman, Victoria A., Jiang, Ji-Lei, Sellers, Joan W., Zuliani, Antoinette M., Treco, Douglas A., Selden, Richard F.

    “…The application of somatic cell gene therapy to large patient populations will require the development of safe and practical approaches to the generation and…”
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  16. 16

    Detection of heteroduplex DNA molecules among the products of Saccharomyces cerevisiae meiosis by Lichten, M. (National Institutes of Health, Bethesda, MD), Goyon, C, Schultes, N.P, Treco, D, Szostak, J.W, Haber, J.E, Nicolas, A

    “…We have used denaturant-gel electrophoresis to provide a physical demonstration of heteroduplex DNA in the products of yeast meiosis. We examined heteroduplex…”
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  17. 17

    Growth and manipulation of yeast by Treco, D A, Reynolds, A, Lundblad, V

    Published in Current protocols in protein science (01-05-2001)
    “…This unit describes preparation of selected media for growing yeast and also discusses strain storage and revival. Protocols are provided for the assay of…”
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    The Evolutionarily Conserved Repetitive Sequence d(TG·AC)n Promotes Reciprocal Exchange and Generates Unusual Recombinant Tetrads During Yeast Meiosis by Treco, Douglas, Arnheim, Norman

    Published in Molecular and cellular biology (01-11-1986)
    “…We have studied the genetic behavior of the alternating copolymer d(TG·AC) n inserted into a defined position in the genome of the yeast Saccharomyces…”
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    Distribution of Ribosomal Gene Length Variants among Mouse Chromosomes by Arnheim, Norman, Treco, Douglas, Taylor, Benjamin, Eicher, Eva M.

    “…The ribosomal genes (rDNA) in mouse inbred strains have a multichromosomal distribution. Using a structural feature of rDNA [variable length rDNA segment…”
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