Search Results - "Trebbastoni, Alessandro"
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Modulation of the Cannabinoid System: A New Perspective for the Treatment of the Alzheimer's Disease
Published in Current neuropharmacology (01-01-2019)“…The pathogenesis of Alzheimer’s disease (AD) is somewhat complex and has yet to be fully understood. As the effectiveness of the therapy currently available…”
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Motor dysfunction in mild cognitive impairment as tested by kinematic analysis and transcranial magnetic stimulation
Published in Clinical neurophysiology (01-02-2021)“…•Voluntary movement abnormalities can be observed in mild cognitive impairment (MCI).•Abnormal rhythm during repetitive finger movements in MCI patients…”
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Beta-Amyloid Peptide in Tears: An Early Diagnostic Marker of Alzheimer's Disease Correlated with Choroidal Thickness
Published in International journal of molecular sciences (30-01-2023)“…We aimed to evaluate the diagnostic role of Alzheimer's disease (AD) biomarkers in tears as well as their association with retinal and choroidal…”
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Multidimensional assessment of time perception along the continuum of Alzheimer’s Disease and evidence of alterations in subjective cognitive decline
Published in Scientific reports (13-12-2023)“…Timing alterations occur in Alzheimer’s disease (AD), even in early stages (mild cognitive impairment, MCI). Moreover, a stage named subjective cognitive…”
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Parkinsonism is associated with altered primary motor cortex plasticity in frontotemporal dementia–primary progressive aphasia variant
Published in Neurobiology of aging (01-09-2018)“…In frontotemporal dementia (FTD), the behavioral variant (bv-FTD) and nonfluent variant of primary progressive aphasia (nfv-PPA) reflect a prominent…”
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Psychosis of Alzheimer's disease: Neuropsychological and neuroimaging longitudinal study
Published in International journal of geriatric psychiatry (01-11-2019)“…Objectives Psychosis of Alzheimer's disease (AD) may represent a distinct disease phenotype; however, neuropsychological profile and neural basis linked to…”
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Memantine for Refractory Obsessive-Compulsive Disorder: Protocol for a Pragmatic, Double-blind, Randomized, Parallel-Group, Placebo-Controlled, Monocenter Trial
Published in JMIR research protocols (11-05-2023)“…Obsessive-compulsive disorder (OCD) is a psychiatric syndrome characterized by unwanted and repetitive thoughts and repeated ritualistic compulsions for…”
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Altered speech-related cortical network in frontotemporal dementia
Published in Brain stimulation (01-05-2020)“…In healthy subjects (HS), transcranial magnetic stimulation (TMS) demonstrated an increase in motor-evoked potential (MEP) amplitudes during specific…”
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Parkinsonism Is Associated with Altered SMA-Basal Ganglia Structural and Functional Connectivity in Frontotemporal Degeneration
Published in Biomedicines (01-02-2023)“…Patients with frontotemporal degeneration (FTD) often manifest parkinsonism, which likely results from cortical and subcortical degeneration of brain…”
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External Validity of Randomized Controlled Trials on Alzheimer's Disease: The Biases of Frailty and Biological Aging
Published in Frontiers in neurology (27-11-2017)“…To date, the external validity of randomized controlled trials (RCTs) on Alzheimer's disease (AD) has been assessed only considering monodimensional variables…”
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Altered Cortical Synaptic Plasticity in Response to 5-Hz Repetitive Transcranial Magnetic Stimulation as a New Electrophysiological Finding in Amnestic Mild Cognitive Impairment Converting to Alzheimer's Disease: Results from a 4-year Prospective Cohort Study
Published in Frontiers in aging neuroscience (12-01-2016)“…To investigate cortical excitability and synaptic plasticity in amnestic mild cognitive impairment (aMCI) using 5 Hz repetitive transcranial magnetic…”
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Inappropriate Sexual Behaviors Among Community-Dwelling Patients with Dementia
Published in The American journal of geriatric psychiatry (01-04-2017)“…Objective Inappropriate sexual behaviors (ISBs) represent challenging and stressful manifestations of dementia and are highly burdening for patients, families,…”
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The Impact of Frailty on the Risk of Conversion from Mild Cognitive Impairment to Alzheimer's Disease: Evidences from a 5-Year Observational Study
Published in Frontiers in medicine (23-10-2017)“…The frailty construct has increasingly been adopted in the field of cognitive disorders. The aim of the present study was to measure frailty in a cohort of…”
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Choroidal thinning as a new finding in Alzheimer's disease: evidence from enhanced depth imaging spectral domain optical coherence tomography
Published in Journal of Alzheimer's disease (01-01-2014)“…The involvement of retina and its vasculature has been recently described in Alzheimer's disease (AD). However, none of the previous works have yet…”
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Recurrent ischemic stroke secondary to cardiac papillary fibroelastoma
Published in Acta neurologica Belgica (01-06-2024)Get full text
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Attenuation of Choroidal Thickness in Patients With Alzheimer Disease: Evidence From an Italian Prospective Study
Published in Alzheimer disease and associated disorders (01-04-2017)“…INTRODUCTION:To compare the 12-month choroidal thickness (CT) change between Alzheimer disease (AD) patients and normal subjects. METHODS:In this prospective,…”
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Retinal nerve fibre layer thickness changes in Alzheimer’s disease: Results from a 12-month prospective case series
Published in Neuroscience letters (26-08-2016)“…•Progressive thinning of the retinal nerve fibre layer by SD-OCT in AD has been described in this prospective comparative case series on AD patients.•The…”
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Cortical complexity alterations in the medial temporal lobe are associated with Alzheimer's disease psychosis
Published in Aging, Neuropsychology, and Cognition (02-11-2022)“…Psychosis is frequent in Alzheimer's disease (AD) and it is associated with a worse disease course. AD psychosis may represent a distinct AD phenotype, though…”
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Sundowning in Dementia: Clinical Relevance, Pathophysiological Determinants, and Therapeutic Approaches
Published in Frontiers in medicine (27-12-2016)“…Sundowning means the emergence or worsening of neuropsychiatric symptoms (NPS) in the late afternoon or early evening. This syndrome has been recognized since…”
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Musical cognition in Alzheimer's disease: application of the Montreal Battery of Evaluation of Amusia
Published in Annals of the New York Academy of Sciences (01-07-2016)“…The aim of this study was to assess certain musical abilities in 30 patients with Alzheimer's disease (AD) and 30 healthy controls by using the complete…”
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