Search Results - "Travers, B"

Losing Hearts & Minds: Aid and Ideology by Child, Travers B

“…“Hearts and minds” theory contends development aid strengthens community support for counterinsurgents by providing jobs and public goods. Based on field…”
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Roles of UVA radiation and DNA damage responses in melanoma pathogenesis by Khan, Aiman Q., Travers, Jeffrey B., Kemp, Michael G., Menck, C.

“…The growing incidence of melanoma is a serious public health issue that merits a thorough understanding of potential causative risk factors, which includes…”
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New Insights Into the Pathologic Roles of the Platelet-Activating Factor System by Travers, Jeffrey B, Rohan, Joyce G, Sahu, Ravi P

“…Described almost 50 years ago, the glycerophosphocholine lipid mediator Platelet-activating factor (PAF) has been implicated in many pathologic processes…”
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The IGF-1 IGF-1R signaling axis in the skin: a new role for the dermis in aging-associated skin cancer by Lewis, D A, Travers, J B, Somani, A-K, Spandau, D F

“…The appropriate response of human keratinocytes to ultraviolet-B (UVB) is dependent on the activation status of the insulin-like growth factor 1 (IGF-1)…”
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Myeloid-Derived Suppressor Cells and Pancreatic Cancer: Implications in Novel Therapeutic Approaches by Thyagarajan, Anita, Alshehri, Mamdouh Salman A, Miller, Kelly L R, Sherwin, Catherine M, Travers, Jeffrey B, Sahu, Ravi P

“…Pancreatic ductal adenocarcinoma (PDAC) remains a devastating human malignancy with poor prognosis and low survival rates. Several cellular mechanisms have…”
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Impact of Age and Insulin-Like Growth Factor-1 on DNA Damage Responses in UV-Irradiated Human Skin by Kemp, Michael G, Spandau, Dan F, Travers, Jeffrey B

“…The growing incidence of non-melanoma skin cancer (NMSC) necessitates a thorough understanding of its primary risk factors, which include exposure to…”
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A review of biosimilars in psoriasis: impacts on efficacy, safety, access, and a first-hand look at biosimilar cost savings within the department of veterans affairs by Reese, Rebecca, Nanavath, Shiva Ram, Martin, Jennifer, Travers, Jeffrey B, Rohan, Craig A

“…Psoriasis is a chronic immune-mediated systemic disease whose treatment has been revolutionized due to the induction of monoclonal antibody-based biologics…”
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Cytokine Milieu of Atopic Dermatitis, as Compared to Psoriasis, Skin Prevents Induction of Innate Immune Response Genes by Nomura, Ichiro, Goleva, Elena, Howell, Michael D, Hamid, Quatyba A, Ong, Peck Y, Hall, Clifton F, Darst, Marc A, Gao, Bifeng, Boguniewicz, Mark, Travers, Jeffrey B, Leung, Donald Y. M

“…Atopic dermatitis (AD) and psoriasis are the two most common chronic skin diseases. However patients with AD, but not psoriasis, suffer from frequent skin…”
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Mast Cells Regulate Epidermal Barrier Function and the Development of Allergic Skin Inflammation by Sehra, Sarita, Serezani, Ana P.M., Ocaña, Jesus A., Travers, Jeffrey B., Kaplan, Mark H.

“…Atopic dermatitis is a chronic inflammatory skin disease characterized by infiltration of eosinophils, T helper cells, and mast cells. The role of mast cells…”
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Platelet-Activating Factor-Receptor Signaling Mediates Targeted Therapies-Induced Microvesicle Particles Release in Lung Cancer Cells by Chauhan, Shreepa J, Thyagarajan, Anita, Chen, Yanfang, Travers, Jeffrey B, Sahu, Ravi P

“…Microvesicle particles (MVP) secreted by a variety of cell types in response to reactive oxygen species (ROS)-generating pro-oxidative stressors have been…”
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UVB-Induced Microvesicle Particle Release and Its Effects on the Cutaneous Microenvironment by Frommeyer, Timothy C, Gilbert, Michael M, Brittain, Garrett V, Wu, Tongfan, Nguyen, Trang Q, Rohan, Craig A, Travers, Jeffrey B

“…Ultraviolet B radiation (UVB) has profound effects on human skin that results in a broad spectrum of immunological local and systemic responses and is the…”
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Insulin-like Growth Factor 1 Receptor Signaling Is Required for Optimal ATR-CHK1 Kinase Signaling in Ultraviolet B (UVB)-irradiated Human Keratinocytes by Kemp, Michael G., Spandau, Dan F., Simman, Richard, Travers, Jeffrey B.

“…UVB wavelengths of light induce the formation of photoproducts in DNA that are potentially mutagenic if not properly removed by the nucleotide excision repair…”
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Infliximab Maintenance Therapy for Fistulizing Crohn's Disease by Sands, Bruce E, Anderson, Frank H, Bernstein, Charles N, Chey, William Y, Feagan, Brian G, Fedorak, Richard N, Kamm, Michael A, Korzenik, Joshua R, Lashner, Bret A, Onken, Jane E, Rachmilewitz, Daniel, Rutgeerts, Paul, Wild, Gary, Wolf, Douglas C, Marsters, Paul A, Travers, Suzanne B, Blank, Marion A, van Deventer, Sander J

“…Infliximab, a monoclonal antibody against tumor necrosis factor, reduces disease activity in patients with Crohn's disease. In this study of patients with…”
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IL-4 Regulates Skin Homeostasis and the Predisposition toward Allergic Skin Inflammation by Sehra, Sarita, Yao, Yongxue, Howell, Michael D, Nguyen, Evelyn T, Kansas, Geoffrey S, Leung, Donald Y. M, Travers, Jeffrey B, Kaplan, Mark H

“…IL-4 promotes the development of Th2 cells and allergic inflammation. In atopic dermatitis lesions, IL-4 decreases the expression of multiple genes associated…”
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Oral and Topical Vitamin D, Sunshine, and UVB Phototherapy Safely Control Psoriasis in Patients with Normal Pretreatment Serum 25-Hydroxyvitamin D Concentrations: A Literature Review and Discussion of Health Implications by McCullough, Patrick J, McCullough, William P, Lehrer, Douglas, Travers, Jeffrey B, Repas, Steven J

“…Vitamin D, sunshine and UVB phototherapy were first reported in the early 1900s to control psoriasis, cure rickets and cure tuberculosis (TB). Vitamin D also…”
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OCRL localizes to the primary cilium: a new role for cilia in Lowe syndrome by NA LUO, WEST, Callah C, MURGA-ZAMALLOA, Carlos A, SUN, Lou, ANDERSON, Ryan M, WELLS, Clark D, WEINREB, Robert N, TRAVERS, Jeffrey B, KHANNA, Hemant, YANG SUN

“…Oculocerebral renal syndrome of Lowe (OCRL or Lowe syndrome), a severe X-linked congenital disorder characterized by congenital cataracts and glaucoma, mental…”
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Inappropriate Testing of Streptococcal Pharyngitis in Children Aged Below 3 Years: Application of Statistical Process Control by Bayless, Sharlo, Bihl, Trevor, Rohan, Craig A., Travers, Jeffrey B., Whitney, Eric

“…Group A strep tests in patients aged below 3 years are not recommended unless the patient has appropriate symptoms and a positive contact or signs of…”
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Ultraviolet B Radiation of Human Skin Generates Platelet-activating Factor Receptor Agonists by Travers, Jared B., Berry, Damien, Yao, Yongxue, Yi, Qiaofang, Konger, Raymond L., Travers, Jeffrey B.

“…Ultraviolet B radiation (UVB) is a potent stimulator of epidermal cytokine production. In addition to cytokines, such as tumor necrosis factor‐alpha (TNF‐α),…”
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Rosacea pathogenesis and therapeutics: current treatments and a look at future targets by Fisher, Garrett W, Travers, Jeffrey B, Rohan, Craig A

“…Rosacea is a chronic inflammatory skin condition associated with a significant health and economic burden from costs and loss of productivity due to seeking…”
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Chloroquine Promotes Apoptosis in Melanoma Cells by Inhibiting BH3 Domain–Mediated PUMA Degradation by Lakhter, Alexander J., Sahu, Ravi P., Sun, Yang, Kaufmann, William K., Androphy, Elliot J., Travers, Jeffrey B., Naidu, Samisubbu R.

“…The Bcl homology-3 (BH3)-only protein p53 upregulated modulator of apoptosis (PUMA) counters Bcl-2 family anti-apoptotic proteins and promotes apoptosis…”
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