Search Results - "Trautwein, Mark"

Modular Protein Expression Toolbox (MoPET), a standardized assembly system for defined expression constructs and expression optimization libraries by Weber, Ernst, Birkenfeld, Jörg, Franz, Jürgen, Gritzan, Uwe, Linden, Lars, Trautwein, Mark

“…The design and generation of an optimal expression construct is the first and essential step in in the characterization of a protein of interest. Besides…”
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TOR1 and TOR2 Have Distinct Locations in Live Cells by Sturgill, Thomas W, Cohen, Adiel, Diefenbacher, Melanie, Trautwein, Mark, Martin, Dietmar E, Hall, Michael N

“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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T cell-mediated elimination of cancer cells by blocking CEACAM6-CEACAM1 interaction by Pinkert, Jessica, Boehm, Hans-Henning, Trautwein, Mark, Doecke, Wolf-Dietrich, Wessel, Florian, Ge, Yingzi, Gutierrez, Eva Maria, Carretero, Rafael, Freiberg, Christoph, Gritzan, Uwe, Luetke-Eversloh, Merlin, Golfier, Sven, Von Ahsen, Oliver, Volpin, Valentina, Sorrentino, Antonio, Rathinasamy, Anchana, Xydia, Maria, Lohmayer, Robert, Sax, Julian, Nur-Menevse, Ayse, Hussein, Abir, Stamova, Slava, Beckmann, Georg, Glueck, Julian Marius, Schoenfeld, Dorian, Weiske, Joerg, Zopf, Dieter, Offringa, Rienk, Kreft, Bertolt, Beckhove, Philipp, Willuda, Joerg

“…Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), a cell surface receptor, is expressed on normal epithelial tissue and highly expressed in…”
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The Prion-like Domain in the Exomer-Dependent Cargo Pin2 Serves as a trans-Golgi Retention Motif by Ritz, Alicja M., Trautwein, Mark, Grassinger, Franziska, Spang, Anne

“…Prion and prion-like domains (PLDs) are found in many proteins throughout the animal kingdom. We found that the PLD in the S. cerevisiae exomer-dependent cargo…”
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Arf1p, Chs5p and the ChAPs are required for export of specialized cargo from the Golgi by Trautwein, M, Schindler, C, Gauss, R, Dengjel, J, Hartmann, E, Spang, A

“…In Saccharomyces cerevisiae, the synthesis of chitin is temporally and spatially regulated through the transport of Chs3p (chitin synthase III) to the plasma…”
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Evaluation of human pancreatic RNase as effector molecule in a therapeutic antibody platform by Schirrmann, Thomas, Frenzel, André, Linden, Lars, Stelte-Ludwig, Beatrix, Willuda, Jörg, Harrenga, Axel, Dübel, Stefan, Müller-Tiemann, Beate, Trautwein, Mark

“…Human antibody-ribonuclease (RNase) fusion proteins, referred to as immunoRNases, have been proposed as an alternative to heterologous immunotoxins, without…”
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New modules for the repeated internal and N-terminal epitope tagging of genes inSaccharomyces cerevisiae by Gauss, Robert, Trautwein, Mark, Sommer, Thomas, Spang, Anne

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Abstract 2791: Physiologically based pharmacokinetic modeling and simulations to estimate the efficacious dose of the CEACAM6 function-blocking antibody BAY 1834942 by Wittemer-Rump, Sabine, Niederalt, Christoph, Willuda, Joerg, Trautwein, Mark, Luetke-Eversloh, Merlin, Doecke, Wolf-Dietrich, Guenther, Clemens, Scheerans, Christian

“…Abstract BAY 1834942 is an immunostimulatory function-blocking (fb) antibody (Ab) against the target carcinoembryonic antigen related cell adhesion molecule 6…”
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Modular Protein Expression Toolbox by Weber, Ernst, Birkenfeld, Jörg, Franz, Jürgen, Gritzan, Uwe, Linden, Lars, Trautwein, Mark

“…The design and generation of an optimal expression construct is the first and essential step in in the characterization of a protein of interest. Besides…”
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Abstract LB-075: Increased T cell- activation resulting from the combination of the anti-CEACAM6 function-blocking antibody BAY 1834942 with checkpoint inhibitors targeting either PD-1/PD-L1 or TIM-3 by Willuda, Joerg, Boehm, Hans-Henning, Pinkert, Jessica, Trautwein, Mark, Doecke, Wolf-Dietrich, Ahsen, Oliver von, Ziegelbauer, Karl, Offringa, Rienk, Kreft, Bertolt, Beckhove, Philipp

“…Abstract CEACAM6 (CD66c) is a novel immune checkpoint regulator suppressing the activity of effector T cells against tumors. CEACAM6 is expressed on tumor…”
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Rational Design of Single Copy Expression Cassettes in Defined Chromosomal Sites Overcomes Intraclonal Cell-to-Cell Expression Heterogeneity and Ensures Robust Antibody Production by Gödecke, Natascha, Herrmann, Sabrina, Hauser, Hansjörg, Mayer-Bartschmid, Anke, Trautwein, Mark, Wirth, Dagmar

“…The expression of endogenous genes as well as transgenes depends on regulatory elements within and surrounding genes as well as their epigenetic modifications…”
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Selective depletion of tumor-infiltrating regulatory T cells with BAY 3375968, a novel Fc-optimized anti-CCR8 antibody by Roider, Helge G., Hoff, Sabine, Tseng, Su-Yi, Berndt, Sandra, Trautwein, Mark, Filarsky, Katharina, Gritzan, Uwe, Camps, Jordi, Nadler, Wiebke Maria, Grudzinska-Goebel, Joanna, Ellinger, Philipp, Pesch, Theresa, Soon, Chai Fen, Geyer, Marcel, Gluske, Katja, Stelte-Ludwig, Beatrix, Gorjánácz, Mátyás

“…Regulatory T cells (Tregs) are known to facilitate tumor progression by suppressing CD8+ T cells within the tumor microenvironment (TME), thereby also…”
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Transport to the plasma membrane is regulated differently early and late in the cell cycle in Saccharomyces cerevisiae by Zanolari, Bettina, Rockenbauch, Uli, Trautwein, Mark, Clay, Lorena, Barral, Yves, Spang, Anne

“…Traffic from the trans-Golgi network to the plasma membrane is thought to occur through at least two different independent pathways. The chitin synthase Chs3p…”
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Abstract 2866: BAY 3375968: An afucosylated anti-CCR8 antibody depleting activated intratumoral regulatory T cells as a cancer immunotherapy by Roider, Helge, Tseng, Su-Yi, Hoff, Sabine, Berndt, Sandra, Filarski, Katharina, Gritzan, Uwe, Stelte-Ludwig, Beatrix, Nadler, Wiebke M., Grudzinska-Goebel, Joanna, Ellinger, Philipp, Trautwein, Mark, Gorjanacz, Matyas

“…Abstract Regulatory T cells (Tregs) play an indispensable role in mediating peripheral tolerance to self-antigens. They can also promote tumor growth by…”
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Abstract 1771: BAY 1834942 is an immunotherapeutic antibody blocking the novel immune checkpoint regulator CEACAM6 (CD66c) by Willuda, Joerg, Trautwein, Mark, Pinkert, Jessica, Doecke, Wolf-Dietrich, Boehm, Hans-Henning, Wessel, Florian, Ge, Yingzi, Gutierrez, Eva Maria, Weiske, Joerg, Freiberg, Christoph, Gritzan, Uwe, Glueck, Julian, Zopf, Dieter, Golfier, Sven, Ahsen, Oliver von, Zierz, Ruprecht, Wittemer-Rump, Sabine, Apeler, Heiner, Karl, Ziegelbauer, Offringa, Rienk, Kreft, Bertolt, Philipp, Beckhove

“…Abstract CEACAM6 (CD66c) was previously shown to act as a novel immune checkpoint regulator suppressing the activity of effector T cells against tumors…”
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New modules for the repeated internal and N‐terminal epitope tagging of genes in Saccharomyces cerevisiae by Gauss, Robert, Trautwein, Mark, Sommer, Thomas, Spang, Anne

“…Epitope tagging is a powerful method for the rapid analysis of protein function. In Saccharomyces cerevisiae epitope tags are introduced easily into…”
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Arf1p provides an unexpected link between COPI vesicles and mRNA in Saccharomyces cerevisiae by Trautwein, Mark, Dengjel, Jörn, Schirle, Markus, Spang, Anne

“…The small GTPase Arf1p is involved in different cellular processes that require its accumulation at specific cellular locations. The recruitment of Arf1p to…”
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Arf1p Provides an Unexpected Link between COPI Vesicles and mRNA in Saccharomyces cerevisiaeD by Trautwein, Mark, Dengjel, Jörn, Schirle, Markus, Spang, Anne

“…The small GTPase Arf1p is involved in different cellular processes that require its accumulation at specific cellular locations. The recruitment of Arf1p to…”
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Policy perspectives on public health for Mexican migrants in California: HIV/AIDS among Mexican migrants and recent immigrants in California and Mexico by MORIN, Stephen F, CARRILLO, Hector, STEWARD, Wayne T, MAIORANA, Andre, TRAUTWEIN, Mark, GOMEZ, Cynthia A

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Policy Perspectives on Public Health For Mexican Migrants in California by Morin, Stephen F, Carrillo, Héctor, Steward, Wayne T, Maiorana, Andre, Trautwein, Mark, Gómez, Cynthia A

“…This analysis focuses on public policies that affect primary HIV prevention and access to HIV care for Mexican migrants residing in California. Policy or…”
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