Search Results - "Traum, Annalena"
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The CD177 c.1291A Allele Leads to a Loss of Membrane Expression and Mimics a CD177-Null Phenotype
Published in International journal of molecular sciences (01-03-2024)“…CD177 is a glycosyl phosphatidyl inositol (GPI)-linked, neutrophil-specific glycoprotein that in 3-5% of normal individuals is absent from all neutrophils. The…”
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Characterization of CD177‐reactive iso‐ and auto‐antibodies
Published in Transfusion (Philadelphia, Pa.) (01-06-2021)“…Background CD177 is a surface protein on neutrophils and a main mediator for the surface expression of proteinase 3 (PR3). Its functions are largely unknown…”
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Current Anti-HPA-1a Standard Antibodies React with the β3 Integrin Subunit but not with αIIbβ3 and αvβ3 Complexes
Published in Thrombosis and haemostasis (01-11-2019)“…Fetal/neonatal alloimmune thrombocytopenia (FNAIT) results from maternal alloantibodies (abs) reacting with fetal platelets expressing paternal human platelet…”
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The ICD177/I c.1291A Allele Leads to a Loss of Membrane Expression and Mimics a CD177-Null Phenotype
Published in International journal of molecular sciences (01-03-2024)“…CD177 is a glycosyl phosphatidyl inositol (GPI)-linked, neutrophil-specific glycoprotein that in 3–5% of normal individuals is absent from all neutrophils. The…”
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The tumor suppressor RASSF1A induces the YAP1 target gene ANKRD1 that is epigenetically inactivated in human cancers and inhibits tumor growth
Published in Oncotarget (24-10-2017)“…The Hippo pathway regulates organ size, growth and comprises several tumor related factors, including the oncoprotein YAP1 and the tumor suppressor RASSF1A. is…”
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Transfusion of target antigens to preimmunized recipients: a new mechanism in transfusion-related acute lung injury
Published in Blood advances (26-10-2021)“…Transfusion-related lung injury (TRALI) is a serious side effect of blood transfusion. Exclusion of antibody carriers from the donor pool has significantly…”
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Molecular and Functional Characterization of Fcγ Receptor IIIb-Ligand Interaction: Implications for Neutrophil-Mediated Immune Mechanisms in Malaria
Published in Infection and immunity (01-08-2018)“…The Fcγ receptor IIIb (FcγRIIIb) is a low-affinity receptor of IgG and is essential in neutrophil-mediated effector functions. Different allelic forms of…”
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