Search Results - "Traub, Stefanie"

Functional human iPSC-derived alveolar-like cells cultured in a miniaturized 96‑Transwell air–liquid interface model by Bluhmki, Teresa, Traub, Stefanie, Müller, Ann-Kathrin, Bitzer, Sarah, Schruf, Eva, Bammert, Marie-Therese, Leist, Marcel, Gantner, Florian, Garnett, James P, Heilker, Ralf

“…In order to circumvent the limited access and donor variability of human primary alveolar cells, directed differentiation of human pluripotent stem cells…”
Get full text

hiPS Cell-Derived Neurons for High-Throughput Screening by Traub, Stefanie, Heilker, Ralf

“…Human induced pluripotent stem (hiPS) cell-derived neurons promise to provide better model cells for drug discovery in the context of neurodegenerative and…”
Get more information

iPS cell derived neuronal cells for drug discovery by Heilker, Ralf, Traub, Stefanie, Reinhardt, Peter, Schöler, Hans R, Sterneckert, Jared

“…Highlights • iPS cell based models should be more predictive than current platforms. • A promising new concept is target-focused screening in iPS cell based…”
Get full text

Pharmaceutical Characterization of Tropomyosin Receptor Kinase B-Agonistic Antibodies on Human Induced Pluripotent Stem (hiPS) Cell-Derived Neurons by Traub, Stefanie, Stahl, Heiko, Rosenbrock, Holger, Simon, Eric, Florin, Lore, Hospach, Lisa, Hörer, Stefan, Heilker, Ralf

“…Brain-derived neurotrophic factor (BDNF) is a central modulator of neuronal development and synaptic plasticity in the central nervous system. This renders the…”
Get more information

Differentiation of hiPS Cells into Definitive Endoderm for High-Throughput Screening by Bluhmki, Teresa, Traub, Stefanie, Schruf, Eva, Garnett, James, Gantner, Florian, Bischoff, Daniel, Heilker, Ralf

“…In drug discovery, there is an increasing demand for more physiological in vitro models that recapitulate the disease situation in patients. Human induced…”
Get more information

Upscaling of hiPS Cell-Derived Neurons for High-Throughput Screening by Traub, Stefanie, Stahl, Heiko, Rosenbrock, Holger, Simon, Eric, Heilker, Ralf

“…The advent of human-induced pluripotent stem (hiPS) cell-derived neurons promised to provide better model cells for drug discovery in the context of the…”
Get more information

Carboxymefloquine, the major metabolite of the antimalarial drug mefloquine, induces drug-metabolizing enzyme and transporter expression by activation of pregnane X receptor by Piedade, Rita, Traub, Stefanie, Bitter, Andreas, Nüssler, Andreas K, Gil, José P, Schwab, Matthias, Burk, Oliver

“…Malaria patients are frequently coinfected with HIV and mycobacteria causing tuberculosis, which increases the use of coadministered drugs and thereby enhances…”
Get full text