Search Results - "Trask, B. J"

Members of the olfactory receptor gene family are contained in large blocks of DNA duplicated polymorphically near the ends of human chromosomes by TRASK, B. J, FRIEDMAN, C, KUO, W.-L, MASSA, H, MORRISH, T, NAYLOR, S, NGUYEN, O. T. H, ROUQUIER, S, SMITH, T, WONG, D. J, YOUNGBLOM, J, VAN DEN ENGH, G, MARTIN-GALLARDO, A, ROWEN, L, AKINBAMI, C, BLANKENSHIP, J, COLLINS, C, GIORGI, D, IADONATO, S, JOHNSON, F

“…We have identified three new members of the olfactory receptor (OR) gene family within a large segment of DNA that is duplicated with high similarity near many…”
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Distribution of olfactory receptor genes in the human genome by Rouquier, Sylvie, Trask, Barbara J, Brand-Arpon, Véronique, Engh, Ger van den, Taviaux, Sylvie, Demaille, Jacques, Giorgi, Dominique

“…We demonstrate that members of the olfactory receptor (OR) gene family are distributed on all but a few human chromosomes. Through FISH analysis, we show that…”
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Evidence for the Organization of Chromatin in Megabase Pair-Sized Loops Arranged along a Random Walk Path in the Human G0/G1 Interphase Nucleus by Yokota, Hiroki, van den Engh, Ger, Hearst, John E., Sachs, Rainer K., Trask, Barbara J.

“…We determined the folding of chromosomes in interphase nuclei by measuring the distance between points on the same chromosome. Over 25,000 measurements were…”
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DNA duplication associated with Charcot-Marie-Tooth disease type 1A by Lupski, J R, de Oca-Luna, R M, Slaugenhaupt, S, Pentao, L, Guzzetta, V, Trask, B J, Saucedo-Cardenas, O, Barker, D F, Killian, J M, Garcia, C A, Chakravarti, A, Patel, P I

“…Charcot-Marie-tooth disease type 1A (CMT1A) was localized by genetic mapping to a 3 cM interval on human chromosome 17p. DNA markers within this interval…”
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Mutations in the BRCA1-associated RING domain (BARD1) gene in primary breast, ovarian and uterine cancers by TO HOA THAI, FENGHE DU, MILLER, D. S, TRASK, B. J, BAER, R, BOWCOCK, A. M, TSAN, J. T, YING JIN, PHUNG, A, SPILLMAN, M. A, MASSA, H. F, MULLER, C. Y, ASHFAQ, R, MATHIS, J. M

“…Germline alterations of BRCA1 result in susceptibility to breast and ovarian cancer. The protein encoded by BRCA1 interacts in vivo with the BRCA1-associated…”
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Androgen Receptor YAC Transgenic Mice Carrying CAG 45 Alleles Show Trinucleotide Repeat Instability by La Spada, A. R., Peterson, K. R., Meadows, S. A., McClain, M. E., Jeng, G., Chmelar, R. S., Haugen, H. A., Chen, K., Singer, M. J., Moore, D., Trask, B. J., Fischbeck, K. H., Clegg, C. H., McKnight, G. S.

“…X-linked spinal and bulbar muscular atrophy (SBMA) is caused by a CAG repeat expansion in the first exon of the androgen receptor (AR) gene. Disease-associated…”
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A New Method for Straightening DNA Molecules for Optical Restriction Mapping by Yokota, Hiroki, Johnson, Forrester, Lu, Hongbo, Robinson, R. Maxwell, Belu, Anna M., Garrison, Michael D., Ratner, Buddy D., Trask, Barbara J., Miller, David L.

“…We have developed an improved method of straightening DNA molecules for use in optical restriction mapping. The DNA was straightened on…”
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Large Multi-Chromosomal Duplications Encompass Many Members of the Olfactory Receptor Gene Family in the Human Genome by Trask, Barbara J., Massa, Hillary, Brand-Arpon, Veronique, Chan, Kin, Friedman, Cynthia, Nguyen, Oanh T., Eichler, Evan, van den Engh, Ger, Rouquier, Sylvie, Shizuya, Hiroaki, Giorgi, Dominique

“…The human genome contains thousands of genes that encode a diverse repertoire of odorant receptors (ORs). We report here on the identification and chromosomal…”
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Identification and localization of the gene for EXTL, a third member of the multiple exostoses gene family by Wise, C A, Clines, G A, Massa, H, Trask, B J, Lovett, M

“…Hereditary multiple exostoses (EXT) is an autosomal dominant disorder characterized by multiple bony outgrowths from the juxtaepiphyseal region of long bones…”
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Complete physical map of the common deletion region in Williams syndrome and identification and characterization of three novel genes by XUN MENG, XIAOJUN LU, ZHIZHONG LI, GREEN, E. D, MASSA, H, TRASK, B. J, MORRIS, C. A, KEATING, M. T

“…Williams syndrome (WS) is a contiguous gene deletion disorder caused by haploinsufficiency of genes at 7q11.23. We have shown that hemizygosity of elastin is…”
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Early dihydrofolate reductase gene amplification events in CHO cells usually occur on the same chromosome arm as the original locus by TRASK, B. J, HAMLIN, J. L

“…We used fluorescence in situ hybridization to examine the products of early DNA sequence amplification events in CHO cells. Nine independent populations of…”
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Human cytogenetics: 46 chromosomes, 46 years and counting by Trask, Barbara J

“…Human cytogenetics was born in 1956 with the fundamental, but empowering, discovery that normal human cells contain 46 chromosomes. Since then, this field and…”
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Estimating Genomic Distance from DNA Sequence Location in Cell Nuclei by a Random Walk Model by van den Engh, Ger, Sachs, Rainer, Trask, Barbara J.

“…The folding of chromatin in interphase cell nuclei was studied by fluorescent in situ hybridization with pairs of unique DNA sequence probes. The sites of DNA…”
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Radiation-produced chromosome aberrations: colourful clues by Sachs, Rainer K, Hlatky, Lynn R, Trask, Barbara J

“…Ionizing radiation produces many chromosome aberrations. A rich variety of aberration types can now be seen with the technique of chromosome painting. Apart…”
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The complex structure and dynamic evolution of human subtelomeres by Trask, Barbara J, Mefford, Heather C

“…Subtelomeres are extraordinarily dynamic and variable regions near the ends of chromosomes. They are defined by their unusual structure: patchworks of blocks…”
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Isolation and characterization of the cDNA encoding human DNA methyltransferase by Yen, Ray-Whay Chiu, Vertino, Paula M., Nelkin, Barry D., Yu, Jane J., El-Deiry, Wafik, Cumaraswamy, Arunthathi, Lennon, Gregory G., Trask, Barbara J., Celano, Paul, Baylin, Stephen B.

“…We have cloned a series of overlapping cDNA clones encoding a 5194 bp transcript for human DNA methyltransferase (DNA MTase). This sequence potentially codes…”
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A Genomic Region Encompassing a Cluster of Olfactory Receptor Genes and a Myosin Light Chain Kinase (MYLK) Gene Is Duplicated on Human Chromosome Regions 3q13–q21 and 3p13 by Brand-Arpon, Véronique, Rouquier, Sylvie, Massa, Hillary, de Jong, Pieter J., Ferraz, Concepcion, Ioannou, Panayiotis A., Demaille, Jacques G., Trask, Barbara J., Giorgi, Dominique

“…The olfactory receptor (OR) multigene family is widely distributed in the human genome. We characterize here a new cluster of four OR genes (HGMW-approved…”
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Different evolutionary processes shaped the mouse and human olfactory receptor gene families by YOUNG, Janet M, FRIEDMAN, Cynthia, WILLIAMS, Eleanor M, ROSS, Joseph A, TONNES-PRIDDY, Lori, TRASK, Barbara J

“…We report a comprehensive comparative analysis of human and mouse olfactory receptor (OR) genes. The OR family is the largest mammalian gene family known. We…”
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Quantification by flow cytometry of chromosome-17 deletions in Smith-Magenis syndrome patients by TRASK, B. J, MEFFORD, H, BALDINI, A, GREENBERG, F, LUPSKI, J. R, PATEL, P. I, VAN DEN ENGH, G, MASSA, H. F, JUYAL, R. C, POTOCKI, L, FINUCANE, B, ABUELO, D. N, WITT, D. R, MAGENIS, E

“…We have used bivariate flow karyotyping to quantify the deletions involving chromosome 17 in sixteen patients with Smith-Magenis syndrome (SMS). The…”
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A Gene Recently Inactivated in Human Defines a New Olfactory Receptor Family in Mammals by Rouquier, Sylvie, Friedman, Cynthia, Delettre, Cécile, van den Engh, Ger, Blancher, Antoine, Crouau-Roy, Brigitte, Trask, Barbara J., Giorgi, Dominique

“…The olfactory receptor (OR) gene family constitutes one of the largest multigene families and is distributed among many chromosomal sites in the human genome…”
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