Search Results - "Transou, Andrea"

Sox2 Promotes Malignancy in Glioblastoma by Regulating Plasticity and Astrocytic Differentiation by Berezovsky, Artem D, Poisson, Laila M, Cherba, David, Webb, Craig P, Transou, Andrea D, Lemke, Nancy W, Hong, Xin, Hasselbach, Laura A, Irtenkauf, Susan M, Mikkelsen, Tom, deCarvalho, Ana C

“…Abstract The high-mobility group–box transcription factor sex-determining region Y–box 2 (Sox2) is essential for the maintenance of stem cells from early…”
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Optimization of Glioblastoma Mouse Orthotopic Xenograft Models for Translational Research by Irtenkauf, Susan M, Sobiechowski, Susan, Hasselbach, Laura A, Nelson, Kevin K, Transou, Andrea D, Carlton, Enoch T, Mikkelsen, Tom, deCarvalho, Ana C

“…Glioblastoma is an aggressive primary brain tumor predominantly localized to the cerebral cortex. We developed a panel of patient-derived mouse orthotopic…”
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Optimization of high grade glioma cell culture from surgical specimens for use in clinically relevant animal models and 3D immunochemistry by Hasselbach, Laura A, Irtenkauf, Susan M, Lemke, Nancy W, Nelson, Kevin K, Berezovsky, Artem D, Carlton, Enoch T, Transou, Andrea D, Mikkelsen, Tom, deCarvalho, Ana C

“…Glioblastomas, the most common and aggressive form of astrocytoma, are refractory to therapy, and molecularly heterogeneous. The ability to establish cell…”
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Anaplastic meningioma: octreotide therapy for a case of recurrent and progressive intracranial disease by Rammo, Richard, Rock, Adam, Transou, Andrea, Raghunathan, Aditya, Rock, Jack

“…Meningiomas are common intracranial tumors categorized as Grades I-III per the current WHO guidelines. A small percentage of meningiomas are Grades II and III,…”
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CSIG-10. PLATELET-DERIVED GROWTH FACTOR RECEPTOR ALPHA ONCOGENE DEPENDENCY IN GLIOBLASTOMA by Berezovsky, Artem, Datta, Indrani, She, Ruicong, Transou, Andrea, Irtenkauf, Susan, Hasselbach, Laura, Poisson, Laila, deCarvalho, Ana

“…Abstract PDGFRA is the second most frequently amplified gene encoding receptor tyrosine kinase in adult glioblastoma (GBM), oftentimes as extrachromosomal…”
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CSIG-06. PLATELET DERIVED GROWTH FACTOR RECEPTOR ALPHA AS AN ONCOGENIC DRIVER IN GLIOBLASTOMA by Berezovsky, Artem, Irtenkauf, Susan, Transou, Andrea, Hasselbach, Laura, Mikkelsen, Tom, de Carvalho, Ana

“…Abstract Activated platelet derived growth factor receptor alpha (PDGFRα) is essential for the maintenance of oligodendrocyte progenitors. Differential…”
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Abstract 1505: Platelet derived growth factor receptor alpha oncogene dependency in glioblastoma by Berezovsky, Artem D., Irtenkauf, Susan M., Transou, Andrea D., Hasselbach, Laura A., Mikkelsen, Tom, deCarvalho, Ana C.

“…Abstract Platelet-derived growth factor receptor alpha (PDGFRA) is a ligand-activated receptor tyrosine kinase (RTK) involved in neurodevelopment. In pediatric…”
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Abstract 2519: Identification of novel MET fusion transcript amplification in glioblastoma by Nuga, Oluwademilade, deCarvalho, Ana, Meng, Yuling, Hasselbach, Laura, Nelson, Kevin, Irtenkauf, Susan, Transou, Andrea

“…Abstract Glioblastoma (GBM) is the most common and aggressive primary CNS malignant tumor with a 15.2% 2 year survival rate for tumors diagnosed between 2008…”
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The Epigenetic Evolution of Glioma Is Determined by the IDH1 Mutation Status and Treatment Regimen by Malta, Tathiane M, Sabedot, Thais S, Morosini, Natalia S, Datta, Indrani, Garofano, Luciano, Vallentgoed, Wies, Varn, Frederick S, Aldape, Kenneth, D'Angelo, Fulvio, Bakas, Spyridon, Barnholtz-Sloan, Jill S, Gan, Hui K, Hasanain, Mohammad, Hau, Ann-Christin, Johnson, Kevin C, Cazacu, Simona, deCarvalho, Ana C, Khasraw, Mustafa, Kocakavuk, Emre, Kouwenhoven, Mathilde C M, Migliozzi, Simona, Niclou, Simone P, Niers, Johanna M, Ormond, D Ryan, Paek, Sun Ha, Reifenberger, Guido, Sillevis Smitt, Peter A, Smits, Marion, Stead, Lucy F, van den Bent, Martin J, Van Meir, Erwin G, Walenkamp, Annemiek, Weiss, Tobias, Weller, Michael, Westerman, Bart A, Ylstra, Bauke, Wesseling, Pieter, Lasorella, Anna, French, Pim J, Poisson, Laila M, Verhaak, Roel G W, Iavarone, Antonio, Noushmehr, Houtan

“…Tumor adaptation or selection is thought to underlie therapy resistance in glioma. To investigate longitudinal epigenetic evolution of gliomas in response to…”
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Detection of diagnostic and prognostic methylation-based signatures in liquid biopsy specimens from patients with meningiomas by Herrgott, Grayson A., Snyder, James M., She, Ruicong, Malta, Tathiane M., Sabedot, Thais S., Lee, Ian Y., Pawloski, Jacob, Podolsky-Gondim, Guilherme G., Asmaro, Karam P., Zhang, Jiaqi, Cannella, Cara E., Nelson, Kevin, Thomas, Bartow, deCarvalho, Ana C., Hasselbach, Laura A., Tundo, Kelly M., Newaz, Rehnuma, Transou, Andrea, Morosini, Natalia, Francisco, Victor, Poisson, Laila M., Chitale, Dhananjay, Mukherjee, Abir, Mosella, Maritza S., Robin, Adam M., Walbert, Tobias, Rosenblum, Mark, Mikkelsen, Tom, Kalkanis, Steven, Tirapelli, Daniela P. C., Weisenberger, Daniel J., Carlotti, Carlos G., Rock, Jack, Castro, Ana Valeria, Noushmehr, Houtan

“…Recurrence of meningiomas is unpredictable by current invasive methods based on surgically removed specimens. Identification of patients likely to recur using…”
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TMOD-06. HIGH INCIDENCE OF TUMORS AFTER TREATMENT WITH A DNA-ALKYLATING AGENT IN MOUSE STRAINS COMMONLY USED IN PRE-CLINICAL STUDIES by Irtenkauf, Susan, Hasselbach, Laura, Transou, Andrea, Poisson, Laila, Noushmehr, Houtan, Rybkin, Igor, deCarvalho, Ana

“…Abstract Glioblastoma (GBM) is commonly treated with the DNA-alkylating agent temozolomide (TMZ). Silencing O6-methylguanine-DNA methyltransferase (MGMT) by…”
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Abstract 3491: Heterogeneous extrachromosomal amplification of mutant PDGFRA is associated with an aggressive phenotype in glioblastoma by Berezovsky, Artem D., Transou, Andrea D., Irtenkauf, Susan M., Hasselbach, Laura A., Koeman, Julie, Kim, Hoon, Verhaak, Roel G., Mikkelsen, Tom, Poisson, Laila M., deCarvalho, Ana C.

“…Abstract Background & Objective: Receptor tyrosine kinase (RTK) signaling is altered in over 80% of glioblastoma (GBM) cases, frequently through gene…”
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SAT587 Methylation-based Machine Learning Classifiers Discriminate Sellar Tumors By Lobe Origin Using Liquid Biopsy Or Surgical Specimens by Herrgott, Grayson A, Asmaro, Karam P, Wells, Michael, Nelson, Kevin, Thomas, Bartow, Hasselbach, Laura A, Transou, Andrea, Cazacu, Simona, Tundo, Kelly M, Nadimidla, Sudha, Scarpace, Lisa, Barnholtz-Sloan, Jill, Sloan, Andrew E, Selman, Warren R, deCarvalho, Ana C, Mukherjee, Abir, Robin, Adam M, Lee, Ian Y, Craig, John, Kalkanis, Steven, Snyder, James, Walbert, Tobias, Rock, Jack, Noushmehr, Houtan, Barros Castro, Ana Valeria

“…Abstract Disclosure: G.A. Herrgott: None. K.P. Asmaro: None. M. Wells: None. K. Nelson: None. B. Thomas: None. L.A. Hasselbach: None. A. Transou: None. S…”
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Sox2 Promotes Malignancy in Glioblastoma by Regulating Plasticity and Astrocytic Differentiation12 by Berezovsky, Artem D., Poisson, Laila M., Cherba, David, Webb, Craig P., Transou, Andrea D., Lemke, Nancy W., Hong, Xin, Hasselbach, Laura A., Irtenkauf, Susan M., Mikkelsen, Tom, deCarvalho, Ana C.

“…The high-mobility group–box transcription factor sex-determining region Y–box 2 (Sox2) is essential for the maintenance of stem cells from early development to…”
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Optimization of High Grade Glioma Cell Culture from Surgical Specimens for Use in Clinically Relevant Animal Models and 3D Immunochemistry by Hasselbach, Laura A., Irtenkauf, Susan M., Lemke, Nancy W., Nelson, Kevin K., Berezovsky, Artem D., Carlton, Enoch T., Transou, Andrea D., Mikkelsen, Tom, deCarvalho, Ana C.

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