Search Results - "Tran, UyenPhuong"
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Coenzyme Q supplementation or over-expression of the yeast Coq8 putative kinase stabilizes multi-subunit Coq polypeptide complexes in yeast coq null mutants
Published in Biochimica et biophysica acta (01-04-2014)“…Coenzyme Q biosynthesis in yeast requires a multi-subunit Coq polypeptide complex. Deletion of any one of the COQ genes leads to respiratory deficiency and…”
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Journal Article -
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Endogenous synthesis of coenzyme Q in eukaryotes
Published in Mitochondrion (01-06-2007)“…Coenzyme Q (Q) functions in the mitochondrial respiratory chain and serves as a lipophilic antioxidant. There is increasing interest in the use of Q as a…”
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Journal Article -
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Expression of the human atypical kinase ADCK3 rescues coenzyme Q biosynthesis and phosphorylation of Coq polypeptides in yeast coq8 mutants
Published in Biochimica et biophysica acta (01-05-2011)“…Coenzyme Q (ubiquinone or Q) is a lipid electron and proton carrier in the electron transport chain. In yeast Saccharomyces cerevisiae eleven genes, designated…”
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Journal Article -
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Small Molecule Intervention in a Protein Kinase C-Gli Transcription Factor Axis
Published in ACS chemical biology (19-06-2020)“…Aberrations in the Hedgehog (Hh) signaling pathway are responsible for a broad range of human cancers, yet only a subset rely on the activity of the clinical…”
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Journal Article -
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Saccharomyces cerevisiae Coq9 polypeptide is a subunit of the mitochondrial coenzyme Q biosynthetic complex
Published in Archives of biochemistry and biophysics (01-07-2007)“…Coenzyme Q (Q) is a redox active lipid that is an essential component of the electron transport chain. Here, we show that steady state levels of Coq3, Coq4,…”
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Journal Article -
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Entamoeba histolytica Induces Intestinal Cathelicidins but Is Resistant to Cathelicidin-Mediated Killing
Published in Infection and Immunity (01-01-2012)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Complementation of Saccharomyces cerevisiae coq7 mutants by mitochondrial targeting of the Escherichia coli UbiF polypeptide: two functions of yeast Coq7 polypeptide in coenzyme Q biosynthesis
Published in The Journal of biological chemistry (16-06-2006)“…Coenzyme Q (ubiquinone or Q) functions in the respiratory electron transport chain and serves as a lipophilic antioxidant. In the budding yeast Saccharomyces…”
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Journal Article -
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Biological evaluation of indolactams for in vitro bryostatin 1-like activity
Published in Bioorganic & medicinal chemistry letters (01-01-2024)“…[Display omitted] Small molecule activators of protein kinase C (PKC) have traditionally been classified as either tumor promoters or suppressors. Although…”
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Journal Article -
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Unstructured linker regions play a role in the differential splicing activities of paralogous RNA binding proteins PTBP1 and PTBP2
Published in The Journal of biological chemistry (01-03-2024)“…RNA Binding Proteins regulate, in part, alternative pre-mRNA splicing and, in turn, gene expression patterns. Polypyrimidine tract binding proteins PTBP1 and…”
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Journal Article -
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The total synthesis of (−)-indolactam I
Published in Tetrahedron (09-08-2019)“…The first total synthesis of (−)-indolactam I (1) is reported. An efficient synthetic route was established to furnish the natural product in 8 steps. This…”
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Journal Article -
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Complementation of Saccharomyces cerevisiae coq7 Mutants by Mitochondrial Targeting of the Escherichia coli UbiF Polypeptide
Published in The Journal of biological chemistry (16-06-2006)“…Coenzyme Q (ubiquinone or Q) functions in the respiratory electron transport chain and serves as a lipophilic antioxidant. In the budding yeast Saccharomyces…”
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Journal Article -
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Indolactam Dipeptides as Nanomolar Gli Inhibitors
Published in ACS medicinal chemistry letters (14-07-2022)“…The Gli transcription factors within the Hedgehog (Hh) signaling pathway play essential roles in human development. However, the reactivation of Gli proteins…”
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Expression of Human ADCK3 restores Coenzyme Q biosynthesis and Phosphorylation of Coq polypeptides in yeast abc1/coq8 mutants
Published in The FASEB journal (01-04-2010)“…Coenzyme Q (ubiquinone or Q) is a lipid electron carrier in the electron transport chain. In yeast Saccharomyces cerevisiae nine genes, designated COQ1 through…”
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Journal Article -
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Characterization of a Coenzyme Q biosynthetic complex in Saccharomyces cerevisiae
Published in The FASEB journal (01-04-2010)“…Coenzyme Q (Q) is a critical molecule for proper functioning of the electron transport chain in mitochondrial respiration. Q is synthesized by a series of…”
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Journal Article -
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Characterization of Coq2 and Coq7 proteins, dual function polypeptides in Saccharomyces cerevisiae coenzyme Q biosynthesis
Published 01-01-2007“…Coenzyme Q (ubiquinone or Q) is an isoprenylated benzoquinone lipid found in various cellular compartments of eukaryotic cells. Besides its function in the…”
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Dissertation -
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Characterization of Coq2 and Coq7 proteins, dual function polypeptides in Saccharomyces cerevisiae coenzyme Q biosynthesis
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Dissertation