Search Results - "Tran, Tri M"

Improved vancomycin dosing in children using area under the curve exposure by Le, Jennifer, Bradley, John S, Murray, William, Romanowski, Gale L, Tran, Tu T, Nguyen, Natalie, Cho, Susan, Natale, Stephanie, Bui, Ivilynn, Tran, Tri M, Capparelli, Edmund V

“…: Our objectives were to (1) determine the pharmacokinetic indices of vancomycin in pediatric patients; and (2) compare attainment of 2 target exposures: area…”
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Paradoxical Effects of Endoplasmic Reticulum Aminopeptidase 1 Deficiency on HLA–B27 and Its Role as an Epistatic Modifier in Experimental Spondyloarthritis by Tran, Tri M., Gill, Tejpal, Bennett, Joshua, Hong, Sohee, Holt, Vance, Lindstedt, Anders J., Bakshi, Sufia, Sikora, Keith, Taurog, Joel D., Breban, Maxime, Navid, Fatemeh, Colbert, Robert A.

“…Objective We undertook this study to examine the functional basis for epistasis between endoplasmic reticulum aminopeptidase 1 (ERAP1) and HLA–B27 in…”
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Augmented Renal Clearance Using Population-Based Pharmacokinetic Modeling in Critically Ill Pediatric Patients by Avedissian, Sean N, Bradley, Erin, Zhang, Diana, Bradley, John S, Nazer, Lama H, Tran, Tri M, Nguyen, Austin, Le, Jennifer

“…The objectives of this study were to: 1) evaluate the prevalence of augmented renal clearance in critically ill pediatric patients using vancomycin clearance;…”
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Bayesian Estimation of Vancomycin Pharmacokinetics in Obese Children: Matched Case-Control Study by Le, Jennifer, PharmD, MAS, FCCP, FCSHP, BCPS-ID, Capparelli, Edmund V., PharmD, Wahid, Uzra, PharmD, Wu, Yi Shuan S., BS, Romanowski, Gale L., PharmD, Tran, Tri M., BS, Nguyen, Austin, Bradley, John S., MD

“…Abstract Purpose The study objective was to compare different body size descriptors that best estimate vancomycin Vd and clearance (CL). Methods Patients…”
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Clinical and Imaging Predictors of Pancreatic Cancer in Patients Hospitalized for Acute Pancreatitis by Luong, Tiffany Q., Chen, Qiaoling, Tran, Tri M., Zhou, Yichen, Lustigova, Eva, Chen, Wansu, Wu, Bechien U.

“…Identifying factors associated with increased short-term risk of pancreatic cancer in the setting of acute pancreatitis (AP) can inform clinical care decisions…”
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HLA-B27 misfolding and ankylosing spondylitis by Colbert, Robert A., Tran, Tri M., Layh-Schmitt, Gerlinde

“…Understanding how HLA-B27 contributes to the pathogenesis of spondyloarthritis continues to be an important goal. Current efforts are aimed largely on three…”
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S1871 A Case Report on Giant Cavernous Hemangiomatosis of the Rectum by Tran, Tri M., Javaherifar, Sara, Kwok, Karl, Dong, Elizabeth, Parker, Rex, Attaluri, Vikram, Sekhon, Harpreet

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Endoplasmic reticulum aminopeptidase 1 and rheumatic disease: functional variation by Tran, Tri M, Colbert, Robert A

“…PURPOSE OF REVIEWTo review the recent developments in our understanding of endoplasmic reticulum (ER) aminopeptidase 1 (ERAP1) function in relation to its role…”
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The Human Leukocyte Antigen (HLA)-B27 Peptidome in Vivo, in Spondyloarthritis-susceptible HLA-B27 Transgenic Rats and the Effect of Erap1 Deletion by Barnea, Eilon, Melamed Kadosh, Dganit, Haimovich, Yael, Satumtira, Nimman, Dorris, Martha L., Nguyen, Mylinh T., Hammer, Robert E., Tran, Tri M., Colbert, Robert A., Taurog, Joel D., Admon, Arie

“…HLA-B27 is a class I major histocompatibility (MHC-I) allele that confers susceptibility to the rheumatic disease ankylosing spondylitis (AS) by an unknown…”
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Low levels of nitrogen addition stimulate decomposition by boreal forest fungi by Allison, Steven D., LeBauer, David S., Ofrecio, M. Rosario, Reyes, Randy, Ta, Anh-Minh, Tran, Tri M.

“…Climate warming and associated increases in nutrient mineralization may increase the availability of soil nitrogen (N) in high latitude ecosystems, such as…”
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ERAP1 reduces accumulation of aberrant and disulfide-linked forms of HLA-B27 on the cell surface by Tran, Tri M., Hong, Sohee, Edwan, Jehad H., Colbert, Robert A.

“…•ERAP1 limits cell surface expression of aberrant disulfide-linked forms of HLA-B27.•While limiting expression of aberrant forms of HLA-B27, ERAP1 has no…”
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280 Multiplex immunofluorescence imaging of armored CAR T cells in pancreatic ductal adenocarcinoma mouse xenografts confirms potent anti-tumor response by Lee, Jia-Jye, Baysac, Kathleen, Tran, Tri M, Chand Thakuri, Bal Krishna, Nurmukhambetova, Saule, Tran, Ngoc, Steimle, Brittany, Hu, Peirong, Schneider, Dina

“…BackgroundChimeric antigen receptor (CAR) T-cells are a promising modality for the treatment of solid tumors, however their functionality to date has been…”
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TNFα-induced macrophage death via caspase-dependent and independent pathways by Tran, Tri M, Temkin, Vladislav, Shi, Bo, Pagliari, Lisa, Daniel, Soizic, Ferran, Christiane, Pope, Richard M

“…Macrophages are the principal source of TNFα, yet they are highly resistant to TNFα-mediated cell death. Previously, employing in vitro differentiated human…”
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Fr347 PROGRESSION OF MORPHOLOGIC CHANGES IN PATIENTS WITH CHRONIC PANCREATITIS: FINDINGS FROM A REGIONAL INTEGRATED HEALTHCARE SYSTEM by Tran, Tri M., Wu, Bechien U., Chen, Wansu, Chen, Qiaoling, Luong, Tiffany Q.

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Fr010 THE DIFFERENTIAL IMPACT OF COVID-19 ON GASTROINTESTINAL ILLNESSES AND RATES OF HOSPITALIZATION: ANALYSIS FROM A REGIONAL INTEGRATED HEALTHCARE SYSTEM by Tran, Tri M., Wu, Bechien U., Dong, Elizabeth, Lee, Janet, Martinez, Mayra

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Spondylarthritis in HLA–B27/human β2‐microglobulin–transgenic rats is not prevented by lack of CD8 by Taurog, Joel D., Dorris, Martha L., Satumtira, Nimman, Tran, Tri M., Sharma, Rohit, Dressel, Ralf, van den Brandt, Jens, Reichardt, Holger M.

“…Objective HLA–B27 predisposes to spondylarthritis by an unknown mechanism. A logical candidate mechanism is through recognition of B27 by CD8+ T cells. The…”
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Additional human β2‐microglobulin curbs HLA–B27 misfolding and promotes arthritis and spondylitis without colitis in male HLA–B27–transgenic rats by Tran, Tri M., Dorris, Martha L., Satumtira, Nimman, Richardson, James A., Hammer, Robert E., Shang, Jie, Taurog, Joel D.

“…Objective Ankylosing spondylitis and related spondylarthritides are associated with HLA–B27, and also with intestinal inflammation, by unknown mechanisms. The…”
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ERAP1 deficiency protects HLA-B27 transgenic rats from arthritis by Tran, Tri M, Gill, Tejpal, Hong, Sohee, Bennett, Joshua, Colbert, Robert A

“…Abstract HLA-B27 (B27) confers a strong predisposition to spondyloarthritis (SpA). Rats transgenic for B27 (B27-TG) develop SpA-like disease with gut…”
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ERAP1 deficiency mitigates HLA-B27 misfolding and ER stress, and protects HLA-B27 transgenic rats from arthritis and orchitis by Tran, Tri M, Gill, Tejpal, Bennett, Joshua, Holt, Vance, Hong, Sohee, Taurog, Joel D, Colbert, Robert A

“…Abstract Endoplasmic reticulum aminopeptidase 1 (ERAP1) is associated with ankylosing spondylitis (AS) in HLA-B27-positive individuals. ERAP1 optimizes peptide…”
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TNF[alpha]-induced macrophage death via caspase-dependent and independent pathways by Tran, Tri M, Temkin, Vladislav, Shi, Bo, Pagliari, Lisa, Daniel, Soizic, Ferran, Christiane, Pope, Richard M

“…Macrophages are the principal source of TNFα, yet they are highly resistant to TNFα-mediated cell death. Previously, employing in vitro differentiated human…”
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