Search Results - "Tran, Tam T.T."

APOE genotype influences the gut microbiome structure and function in humans and mice: relevance for Alzheimer's disease pathophysiology by Tran, Tam T. T., Corsini, Simone, Kellingray, Lee, Hegarty, Claire, Le Gall, Gwénaëlle, Narbad, Arjan, Müller, Michael, Tejera, Noemi, O'Toole, Paul W., Minihane, Anne-Marie, Vauzour, David

“…ABSTRACT Apolipoprotein E (APOE) genotype is the strongest prevalent genetic risk factor for Alzheimer's disease (AD). Numerous studies have provided insights…”
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Exploratory analysis of covariation of microbiota-derived vitamin K and cognition in older adults by McCann, Angela, Jeffery, Ian B, Ouliass, Bouchra, Ferland, Guylaine, Fu, Xueyen, Booth, Sarah L, Tran, Tam TT, O–Toole, Paul W, O–Connor, Eibhlís M

“…Vitamin K has multiple important physiological roles, including blood coagulation and beneficial effects on myelin integrity in the brain. Some intestinal…”
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Cyclotides derived from Viola dalatensis Gagnep: A novel approach for enrichment and evaluation of antimicrobial activity by Dang, Tien T., Tran, Tam T.T., Tran, Gia-Hoa, Pham, Son H., Nguyen, Tuan H.N.

“…Cyclotides, plant-derived cysteine-rich peptides, exhibit a wide range of beneficial biological activities and possess exceptional structural stability…”
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Yeast β‐Glucan Improves Insulin Sensitivity and Hepatic Lipid Metabolism in Mice Humanized with Obese Type 2 Diabetic Gut Microbiota by Mitchelson, Kathleen A. J., Tran, Tam T. T., Dillon, Eugene T., Vlckova, Klara, Harrison, Sabine M., Ntemiri, Alexandra, Cunningham, Katie, Gibson, Irene, Finucane, Francis M., O'Connor, Eibhlís M., Roche, Helen M., O'Toole, Paul W.

“…Scope Gut microbiota alterations are associated with obesity and type 2 diabetes. Yeast β‐glucans are potential modulators of the innate immune‐metabolic…”
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Whole Blueberry and Isolated Polyphenol-Rich Fractions Modulate Specific Gut Microbes in an In Vitro Colon Model and in a Pilot Study in Human Consumers by Ntemiri, Alexandra, Ghosh, Tarini S, Gheller, Molly E, Tran, Tam T T, Blum, Jamie E, Pellanda, Paola, Vlckova, Klara, Neto, Marta C, Howell, Amy, Thalacker-Mercer, Anna, O'Toole, Paul W

“…Blueberry (BB) consumption is linked to improved health. The bioconversion of the polyphenolic content of BB by fermentative bacteria in the large intestine…”
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Prebiotic supplementation in frail older people affects specific gut microbiota taxa but not global diversity by Tran, Tam T T, Cousin, Fabien J, Lynch, Denise B, Menon, Ravi, Brulc, Jennifer, Brown, Jillian R-M, O'Herlihy, Eileen, Butto, Ludovica F, Power, Katie, Jeffery, Ian B, O'Connor, Eibhlís M, O'Toole, Paul W

“…There are complex interactions between aging, frailty, diet, and the gut microbiota; modulation of the gut microbiota by diet could lead to healthier aging…”
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A Comprehensive tRNA Genomic Survey Unravels the Evolutionary History of tRNA Arrays in Prokaryotes by Tran, Tam T T, Belahbib, Hassiba, Bonnefoy, Violaine, Talla, Emmanuel

“…Considering the importance of tRNAs in the translation machinery, scant attention has been paid to tRNA array units defined as genomic regions containing at…”
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Microbiome Transfer Partly Overrides Lack of IL‐1RI Signaling to Alter Hepatic but not Adipose Tissue Phenotype and Lipid Handling following a High‐Fat Diet Challenge by Ralston, Jessica C., Mitchelson, Kathleen A. J., Lynch, Gina M., Tran, Tam T. T., Wang, Hao, Strain, Conall R., Lenighan, Yvonne M., Kennedy, Elaine B., Stanton, Catherine, McGillicuddy, Fiona C., Su, Qiaozhu, O'Toole, Paul W., Roche, Helen M.

“…Scope IL‐1RI‐mediated inflammatory signaling alters metabolic tissue responses to dietary challenges (e.g., high‐fat diet [HFD]). Recent work suggests that…”
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A pilot study of dietary fibres on pathogen growth in an ex vivo colonic model reveals their potential ability to limit vancomycin-resistant Enterococcus expansion by Strain, Ronan, Tran, Tam T.T., Mills, Susan, Stanton, Catherine, Ross, R. Paul

“…Aim: Dietary fibre is important for shaping gut microbiota. The aim of this pilot study was to investigate the impact of dietary fibres on pathogen performance…”
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Cyclotides, Cyclic Peptides Derived from Clitoria ternatea Linn Mature Pods, Hold Promise as Potential Antimicrobial Agent by Tran, Tam T. T., Tran, Gia‐Hoa, Cu, Son T., Pham, Son H., Nguyen, Tuan H. N., Dang, Tien T.

“…Cyclotides, cysteine‐rich peptides, are derived from various plant sources. Within the Fabaceae family, Clitoria ternatea Linn distinguishes itself as the only…”
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A randomized controlled trial of a pharmacist-led intervention to enhance knowledge of Vietnamese patients with type 2 diabetes mellitus by Nguyen, Thao H, Tran, Tam T T, Nguyen, Nguyet K, Diep, Han G, Vo, Son D, Taxis, Katja, Pham, Suol T, Nguyen, Thang

“…We aimed to assess whether a pharmacist-led intervention enhances knowledge, medication adherence and glycemic control in patients with type 2 diabetes…”
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Baker's yeast (1→3)-β-D-glucan Influences Insulin Sensitivity in Mice with Humanized Obese Diabetic Microbiome in High-Fat Diet-Induced Obesity by Mitchelson, Kathleen A. J., de Marco Castro, Elena, Hueston, Cara M., Lynch, Gina M., Keogh, Elaine A., Tran, Tam T.T., Vlckova, Klara, Roche, Helen M., O'Toole, Paul W.

“…Abstract Introduction β-glucans are naturally occurring polysaccharides which have isoform specific immunomodulatory and metabolic properties (1) . Certain…”
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Microbiome transfer between IL-1RI-/- and wild-type mice during high or low-fat feeding alters metabolic tissue functionality but not glucose homeostasis by Ralston, Jessica C., Mitchelson, Kathleen A.J., Lynch, Gina M., Tran, Tam T.T., Strain, Conall R., Lenighan, Yvonne M., Kennedy, Elaine B., McGillicuddy, Fiona C., O'Toole, Paul W., Roche, Helen M.

“…Reduced inflammatory signaling (IL-1RI-/-) alters metabolic responses to dietary challenges (1). Inflammasome deficiency (e.g. IL-18-/-, Asc-/-) can modify gut…”
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Biochemical Function, Molecular Structure and Evolution of an Atypical Thioredoxin Reductase from Desulfovibrio vulgaris by Valette, Odile, Tran, Tam T T, Cavazza, Christine, Caudeville, Elodie, Brasseur, Gaël, Dolla, Alain, Talla, Emmanuel, Pieulle, Laetitia

“…Thioredoxin reductase (TR) regulates the intracellular redox environment by reducing thioredoxin (Trx). In anaerobes, recent findings indicate that the Trx…”
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Loss of MMR and TGFBR2 Increases the Susceptibility to Microbiota-Dependent Inflammation-Associated Colon Cancer by Tosti, Elena, Almeida, Ana S., Tran, Tam T.T., Barbachan e Silva, Mariel, Broin, Pilib Ó., Dubin, Robert, Chen, Ken, Beck, Amanda P., Mclellan, Andrew S., Vilar, Eduardo, Golden, Aaron, O’Toole, Paul W., Edelmann, Winfried

“…Mutations in DNA mismatch repair (MMR) genes are causative in Lynch syndrome and a significant proportion of sporadic colorectal cancers (CRCs). MMR-deficient…”
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Comparative Genome Analysis Provides Insights into Both the Lifestyle of Acidithiobacillus ferrivorans Strain CF27 and the Chimeric Nature of the Iron-Oxidizing Acidithiobacilli Genomes by Tran, Tam T T, Mangenot, Sophie, Magdelenat, Ghislaine, Payen, Emilie, Rouy, Zoé, Belahbib, Hassiba, Grail, Barry M, Johnson, D Barrie, Bonnefoy, Violaine, Talla, Emmanuel

“…The iron-oxidizing species is one of few acidophiles able to oxidize ferrous iron and reduced inorganic sulfur compounds at low temperatures (<10°C). To…”
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