Search Results - "Tran, Nathan L."

Naegleria fowleri: Protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba by Tillery, Logan, Barrett, Kayleigh, Goldstein, Jenna, Lassner, Jared W, Osterhout, Bram, Tran, Nathan L, Xu, Lily, Young, Ryan M, Craig, Justin, Chun, Ian, Dranow, David M, Abendroth, Jan, Delker, Silvia L, Davies, Douglas R, Mayclin, Stephen J, Calhoun, Brandy, Bolejack, Madison J, Staker, Bart, Subramanian, Sandhya, Phan, Isabelle, Lorimer, Donald D, Myler, Peter J, Edwards, Thomas E, Kyle, Dennis E, Rice, Christopher A, Morris, James C, Leahy, James W, Manetsch, Roman, Barrett, Lynn K, Smith, Craig L, Van Voorhis, Wesley C

“…Naegleria fowleri is a pathogenic, thermophilic, free-living amoeba which causes primary amebic meningoencephalitis (PAM). Penetrating the olfactory mucosa,…”
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In vitro reconstitution reveals major differences between human and bacterial cytochrome c synthases by Sutherland, Molly C, Mendez, Deanna L, Babbitt, Shalon E, Tillman, Dustin E, Melnikov, Olga, Tran, Nathan L, Prizant, Noah T, Collier, Andrea L, Kranz, Robert G

“…Cytochromes c are ubiquitous heme proteins in mitochondria and bacteria, all possessing a CXXCH (CysXxxXxxCysHis) motif with covalently attached heme. We…”
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Dual IKZF2 and CK1α degrader targets acute myeloid leukemia cells by Park, Sun-Mi, Miyamoto, David K., Han, Grace Y.Q., Chan, Mandy, Curnutt, Nicole M., Tran, Nathan L., Velleca, Anthony, Kim, Jun Hyun, Schurer, Alexandra, Chang, Kathryn, Xu, Wenqing, Kharas, Michael G., Woo, Christina M.

“…Acute myeloid leukemia (AML) is a hematologic malignancy for which several epigenetic regulators have been identified as therapeutic targets. Here we report…”
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Targeted Protein Degradation: Design Considerations for PROTAC Development by Tran, Nathan L, Leconte, Georges A, Ferguson, Fleur M

“…Targeted protein degradation has recently gained widespread interest as both a novel therapeutic strategy and a useful tool in biomedical research. Targeted…”
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Structure-Function Analysis of the Bifunctional CcsBA Heme Exporter and Cytochrome c Synthetase by Sutherland, Molly C, Tran, Nathan L, Tillman, Dustin E, Jarodsky, Joshua M, Yuan, Jason, Kranz, Robert G

“…Although intracellular heme trafficking must occur for heme protein assembly, only a few heme transporters have been unequivocally discovered and nothing is…”
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Structure-Function Analysis of the Bifunctional CcsBA Heme Exporter and Cytochrome italic toggle="yes">c /italic> Synthetase by Molly C. Sutherland, Nathan L. Tran, Dustin E. Tillman, Joshua M. Jarodsky, Jason Yuan, Robert G. Kranz

“…ABSTRACT Although intracellular heme trafficking must occur for heme protein assembly, only a few heme transporters have been unequivocally discovered and…”
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