Search Results - "Tran, Laurent"
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Virological and immunological impact of integrase inhibitor-based regimens initiated during primary HIV-1 infection
Published in AIDS (London) (15-03-2020)“…DESIGN:Current international guidelines recommend either boosted protease inhibitor (PI/r)-based or integrase inhibitors (INSTI)-based regimens during primary…”
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Evidence for a continuous drift of the HIV-1 species towards higher resistance to neutralizing antibodies over the course of the epidemic
Published in PLoS pathogens (01-07-2013)“…We compared the neutralization sensitivity of early/transmitted HIV-1 variants from patients infected by subtype B viruses at 3 periods of the epidemic…”
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Recent HIV-1 infection contributes to the viral diffusion over the French territory with a recent increasing frequency
Published in PloS one (14-02-2012)“…To analyse the contribution of primary human immunodeficiency virus type 1 (HIV-1) infection (PHI) to the French viral epidemic. HIV-1 pol sequences included…”
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Increasing HIV-1 Non-B Subtype Primary Infections in Patients in France and Effect of HIV Subtypes on Virological and Immunological Responses to Combined Antiretroviral Therapy
Published in Clinical infectious diseases (15-03-2013)“…Background. To analyze the time trends of the viral subtype distributions according to gender, risk group, and geographical origin of the patients in 1128…”
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Intensive five-drug antiretroviral therapy regimen versus standard triple-drug therapy during primary HIV-1 infection (OPTIPRIM-ANRS 147): a randomised, open-label, phase 3 trial
Published in The Lancet infectious diseases (01-04-2015)“…Summary Background Early combination antiretroviral therapy (cART) initiation at the time of primary HIV-1 infection could restrict the establishment of HIV…”
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HIV-1 subtype B-infected MSM may have driven the spread of transmitted resistant strains in France in 2007-12: impact on susceptibility to first-line strategies
Published in Journal of antimicrobial chemotherapy (01-07-2015)“…Our study describes the prevalence of transmitted drug resistance (TDR) among 1318 French patients diagnosed at the time of primary HIV-1 infection (PHI) in…”
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Integrase strand-transfer inhibitor use and cardiovascular events in adults with HIV: an emulation of target trials in the HIV-CAUSAL Collaboration and the Antiretroviral Therapy Cohort Collaboration
Published in The lancet HIV (01-11-2023)“…A recent observational study suggested that the risk of cardiovascular events could be higher among antiretroviral therapy (ART)-naive individuals with HIV who…”
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CD4 T cell decline following HIV seroconversion in individuals with and without CXCR4-tropic virus
Published in Journal of antimicrobial chemotherapy (01-10-2017)“…The natural clinical and immunological courses following HIV seroconversion with CXCR4-tropic or dual-mixed (X4/DM) viruses are controversial. We compared…”
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Prognosis of HIV-associated non-Hodgkin lymphoma in patients starting combination antiretroviral therapy
Published in AIDS (London) (24-09-2009)“…We examined survival and prognostic factors of patients who developed HIV-associated non-Hodgkin lymphoma (NHL) in the era of combination antiretroviral…”
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Evidence for a Continuous Drift of the HIV-1 Species towards Higher Resistance to Neutralizing Antibodies over the Course of the Epidemic: e1003477
Published in PLoS pathogens (01-07-2013)“…We compared the neutralization sensitivity of early/transmitted HIV-1 variants from patients infected by subtype B viruses at 3 periods of the epidemic…”
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No evidence of a change in HIV-1 virulence since 1996 in France
Published in AIDS (London) (19-06-2009)“…We investigated temporal trends in the CD4 cell count and in plasma HIV RNA and total HIV DNA levels measured at the time of primary HIV infection, as proxies…”
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Yearly number of patients diagnosed with primary HIV-1 infection in France estimated by a capture–recapture approach
Published in AIDS (London) (28-11-2006)“…We used a two-source capture-recapture method to estimate the number of patients diagnosed at the time of primary HIV infection in France between 1999 and…”
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