Search Results - "Tran, Julie"
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X-box binding protein 1 is essential for the anti-oxidant defense and cell survival in the retinal pigment epithelium
Published in PloS one (08-06-2012)“…Damage to the retinal pigment epithelium (RPE) is an early event in the pathogenesis of age-related macular degeneration (AMD). X-box binding protein 1 (XBP1)…”
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A connectome of a learning and memory center in the adult Drosophila brain
Published in eLife (18-07-2017)“…Understanding memory formation, storage and retrieval requires knowledge of the underlying neuronal circuits. In , the mushroom body (MB) is the major site of…”
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Curcumin protects retinal cells from light-and oxidant stress-induced cell death
Published in Free radical biology & medicine (01-03-2009)“…Age-related macular degeneration (AMD) is a complex disease that has potential involvement of inflammatory and oxidative stress-related pathways in its…”
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Carbodiimide and Isocyanate Hydroboration by a Cyclic Carbodiphosphorane Catalyst
Published in Chemistry : a European journal (11-01-2024)“…We report hydroboration of carbodiimide and isocyanate substrates catalyzed by a cyclic carbodiphosphorane catalyst. The cyclic carbodiphosphorane outperformed…”
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IFITM-2 and IFITM-3 but Not IFITM-1 Restrict Rift Valley Fever Virus
Published in Journal of Virology (01-08-2013)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Inhibition of de novo ceramide biosynthesis by FTY720 protects rat retina from light-induced degeneration
Published in Journal of lipid research (01-06-2013)“…Light-induced retinal degeneration (LIRD) in albino rats causes apoptotic photoreceptor cell death. Ceramide is a second messenger for apoptosis. We tested…”
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High content image-based screening of a protease inhibitor library reveals compounds broadly active against Rift Valley fever virus and other highly pathogenic RNA viruses
Published in PLoS neglected tropical diseases (01-08-2014)“…High content image-based screening was developed as an approach to test a protease inhibitor small molecule library for antiviral activity against Rift Valley…”
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Duplex One-Step RT-qPCR Assays for Simultaneous Detection of Genomic and Subgenomic RNAs of SARS-CoV-2 Variants
Published in Viruses (17-05-2022)“…A hallmark of severe acute respiratory syndrome virus (SARS-CoV-2) replication is the discontinuous transcription of open reading frames (ORFs) encoding…”
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Engineered Human Cathelicidin Antimicrobial Peptides Inhibit Ebola Virus Infection
Published in iScience (24-04-2020)“…The 2014–2016 West Africa Ebola virus (EBOV) outbreak coupled with the most recent outbreaks in Central Africa underscore the need to develop effective…”
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Protein Kinase R Degradation Is Essential for Rift Valley Fever Virus Infection and Is Regulated by SKP1-CUL1-F-box (SCF)FBXW11-NSs E3 Ligase
Published in PLoS pathogens (01-02-2016)“…Activated protein kinase R (PKR) plays a vital role in antiviral defense primarily by inhibiting protein synthesis and augmenting interferon responses. Many…”
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The Poly(ADP-ribose) Polymerase Enzyme Tankyrase Antagonizes Activity of the β-Catenin Destruction Complex through ADP-ribosylation of Axin and APC2
Published in The Journal of biological chemistry (10-06-2016)“…Most colon cancer cases are initiated by truncating mutations in the tumor suppressor, adenomatous polyposis coli (APC). APC is a critical negative regulator…”
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12
Junin Virus Activates p38 MAPK and HSP27 Upon Entry
Published in Frontiers in cellular and infection microbiology (07-04-2022)“…Junín virus (JUNV), a New World arenavirus, is a rodent-borne virus and the causative agent of Argentine hemorrhagic fever. Humans become infected through…”
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Retinal sphingolipids and their very-long-chain fatty acid-containing species
Published in Investigative ophthalmology & visual science (01-09-2010)“…Recent evidence suggests that ceramide metabolism plays an important role in retinal photoreceptor cell survival and apoptosis. The purpose of this study was…”
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Orally available nucleoside analog UMM-766 provides protection in a murine model of orthopox disease
Published in Microbiology spectrum (02-04-2024)“…Although smallpox has been eradicated, other orthopoxviruses continue to be a public health concern as exemplified by the ongoing Mpox (formerly monkeypox)…”
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Identification of an antioxidant small-molecule with broad-spectrum antiviral activity
Published in Antiviral research (01-01-2012)“…► Identified compound with broad-spectrum antiviral activity. ► Identified compound has anti-oxidant properties. ► Inhibition of oxidative stress for…”
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Evaluating the Abnormality of Bilateral Motor Cortex Activity in Subacute Stroke Patients Executing a Unimanual Motor Task With Increasing Demand on Precision
Published in Frontiers in neurology (25-05-2022)“…Abnormal contralesional M1 activity is consistently reported in patients with compromised upper limb and hand function after stroke. The underlying mechanisms…”
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A Lassa virus live attenuated vaccine candidate that is safe and efficacious in guinea pigs
Published in npj vaccines (17-11-2024)“…Lassa virus (LASV) is a rodent-borne mammarenavirus that causes tens to hundreds of thousands of human infections annually in Western Africa. Approximately 20%…”
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Second generation of diazachrysenes: Protection of Ebola virus infected mice and mechanism of action
Published in European journal of medicinal chemistry (15-01-2019)“…Ebola virus (EBOV) causes a deadly hemorrhagic fever in humans and non-human primates. There is currently no FDA-approved vaccine or medication to counter this…”
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In vivo effect of mutant ELOVL4 on the expression and function of wild-type ELOVL4
Published in Investigative ophthalmology & visual science (25-04-2014)“…Mutations in the elongation of very long chain fatty acids 4 (ELOVL4) gene cause human Stargardt's macular dystrophy 3 (STGD3), a juvenile onset dominant form…”
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Expression and localization of CERKL in the mammalian retina, its response to light-stress, and relationship with NeuroD1 gene
Published in Experimental eye research (01-01-2013)“…Mutations in the Ceramide kinase like (CERKL) gene are associated with retinitis pigmentosa (RP26) and cone-rod dystrophy. CERKL is homologous to Ceramide…”
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