Search Results - "Tran, Chau T H"

A common human TLR1 polymorphism regulates the innate immune response to lipopeptides by Hawn, Thomas R., Misch, E. Ann, Dunstan, Sarah J., Thwaites, Guy E., Lan, Nguyen T. N., Quy, Hoang T., Chau, Tran T. H., Rodrigues, Stephanie, Nachman, Alex, Janer, Marta, Hien, Tran T., Farrar, Jeremy J., Aderem, Alan

“…Toll‐like receptors (TLR) are critical mediators of the immune response to pathogens and human polymorphisms in this gene family regulate inflammatory pathways…”
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Dexamethasone, cerebrospinal fluid matrix metalloproteinase concentrations and clinical outcomes in tuberculous meningitis by Green, Justin A, Tran, Chau T H, Farrar, Jeremy J, Nguyen, Mai T H, Nguyen, Phu H, Dinh, Sinh X, Ho, Nghia D T, Ly, Chuong V, Tran, Hien T, Friedland, Jon S, Thwaites, Guy E

“…Adjunctive dexamethasone reduces mortality from tuberculous meningitis, but how it produces this effect is not known. Matrix metalloproteinases (MMPs) are…”
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Intensified Antituberculosis Therapy in Adults with Tuberculous Meningitis by Heemskerk, A. Dorothee, Bang, Nguyen D, Mai, Nguyen T.H, Chau, Tran T.H, Phu, Nguyen H, Loc, Pham P, Chau, Nguyen V.V, Hien, Tran T, Dung, Nguyen H, Lan, Nguyen T.N, Lan, Nguyen H, Lan, Nguyen N, Phong, Le T, Vien, Nguyen N, Hien, Nguyen Q, Yen, Nguyen T.B, Ha, Dang T.M, Day, Jeremy N, Caws, Maxine, Merson, Laura, Thinh, Tran T.V, Wolbers, Marcel, Thwaites, Guy E, Farrar, Jeremy J

“…Tuberculous meningitis remains highly lethal. In this trial, an intensified regimen of levofloxacin and higher-dose rifampin added to standard therapy was…”
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Randomized controlled trial of artesunate or artemether in Vietnamese adults with severe falciparum malaria by Phu, Nguyen H, Tuan, Phung Q, Day, Nicholas, Mai, Nguyen T H, Chau, Tran T H, Chuong, Ly V, Sinh, Dinh X, White, Nicholas J, Farrar, Jeremy, Hien, Tran T

“…Both artemether and artesunate have been shown to be superior to quinine for the treatment of severe falciparum malaria in Southeast Asian adults, although the…”
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Combination Antifungal Therapy for Cryptococcal Meningitis by Day, Jeremy N, Chau, Tran T.H, Wolbers, Marcel, Mai, Pham P, Dung, Nguyen T, Mai, Nguyen H, Phu, Nguyen H, Nghia, Ho D, Phong, Nguyen D, Thai, Cao Q, Thai, Le H, Chuong, Ly V, Sinh, Dinh X, Duong, Van A, Hoang, Thu N, Diep, Pham T, Campbell, James I, Sieu, Tran P.M, Baker, Stephen G, Chau, Nguyen V.V, Hien, Tran T, Lalloo, David G, Farrar, Jeremy J

“…Determining the best therapy for HIV-associated cryptococcal meningitis in resource-poor settings is controversial. In this trial in Vietnam, initial therapy…”
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Host Genotype-Specific Therapies Can Optimize the Inflammatory Response to Mycobacterial Infections by Tobin, David M., Roca, Francisco J., Oh, Sungwhan F., McFarland, Ross, Vickery, Thad W., Ray, John P., Ko, Dennis C., Zou, Yuxia, Bang, Nguyen D., Chau, Tran T.H., Vary, Jay C., Hawn, Thomas R., Dunstan, Sarah J., Farrar, Jeremy J., Thwaites, Guy E., King, Mary-Claire, Serhan, Charles N., Ramakrishnan, Lalita

“…Susceptibility to tuberculosis is historically ascribed to an inadequate immune response that fails to control infecting mycobacteria. In zebrafish, we find…”
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Human TOLLIP regulates TLR2 and TLR4 signaling and its polymorphisms are associated with susceptibility to tuberculosis by Shah, Javeed A, Vary, Jay C, Chau, Tran T H, Bang, Nguyen D, Yen, Nguyen T B, Farrar, Jeremy J, Dunstan, Sarah J, Hawn, Thomas R

“…Tuberculosis, one of the leading causes of death worldwide, stimulates inflammatory responses with beneficial and pathologic consequences. The regulation and…”
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Common Polymorphisms in the PKP3-SIGIRR-TMEM16J Gene Region Are Associated With Susceptibility to Tuberculosis by Horne, David J., Randhawa, April K., Chau, Tran T. H., Bang, Nguyen D., Yen, Nguyen T. B., Farrar, Jeremy J., Dunstan, Sarah J., Hawn, Thomas R.

“…Background. Tuberculosis has been associated with genetic variation in host immunity. We hypothesized that single-nucleotide polymorphisms (SNPs) in SIGIRR, a…”
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Leukotriene A4 Hydrolase Genotype and HIV Infection Influence Intracerebral Inflammation and Survival From Tuberculous Meningitis by Thuong, Nguyen T. T., Heemskerk, Dorothee, Tram, Trinh T. B., Thao, Le T. P., Ramakrishnan, Lalita, Ha, Vu T. N., Bang, Nguyen D., Chau, Tran T. H., Lan, Nguyen H., Caws, Maxine, Dunstan, Sarah J., Chau, Nguyen V. V., Wolbers, Marcel, Mai, Nguyen T. H., Thwaites, Guy E.

“…Background. Tuberculous meningitis (TBM) is the most devastating form of tuberculosis, yet very little is known about the pathophysiology. We hypothesized that…”
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REL and BHLHE40 Variants Are Associated with IL-12 and IL-10 Responses and Tuberculosis Risk by Shah, Javeed A, Warr, Alex J, Graustein, Andrew D, Saha, Aparajita, Dunstan, Sarah J, Thuong, Nguyen T T, Thwaites, Guy E, Caws, Maxine, Thai, Phan V K, Bang, Nguyen D, Chau, Tran T H, Khor, Chiea Chuen, Li, Zheng, Hibberd, Martin, Chang, Xuling, Nguyen, Felicia K, Hernandez, Carlo A, Jones, Madison A, Sassetti, Christopher M, Fitzgerald, Katherine A, Musvosvi, Munyaradzi, Gela, Anele, Hanekom, Willem A, Hatherill, Mark, Scriba, Thomas J, Hawn, Thomas R

“…The major human genes regulating -induced immune responses and tuberculosis (TB) susceptibility are poorly understood. Although IL-12 and IL-10 are critical…”
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HIV-1 drug resistance in antiretroviral-naive individuals with HIV-1-associated tuberculous meningitis initiating antiretroviral therapy in Vietnam by Thao, Vu P, Le, Thuy, Török, Estee M, Yen, Nguyen T B, Chau, Tran T H, Jurriaans, Suzanne, van Doorn, H Rogier, van Doorn, Rogier H, de Jong, Menno D, Farrar, Jeremy J, Dunstan, Sarah J

“…Access to antiretroviral therapy (ART) for HIV-infected individuals in Vietnam is rapidly expanding, but there are limited data on HIV drug resistance (HIVDR)…”
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A prospective descriptive study of cryptococcal meningitis in HIV uninfected patients in Vietnam - high prevalence of Cryptococcus neoformans var grubii in the absence of underlying disease by Chau, Tran Th, Mai, Nguyen H, Phu, Nguyen H, Nghia, Ho D, Chuong, Ly V, Sinh, Dinh X, Duong, Van A, Diep, Pham T, Campbell, James I, Baker, Stephen, Hien, Tran T, Lalloo, David G, Farrar, Jeremy J, Day, Jeremy N

“…Most cases of cryptococcal meningitis occur in patients with HIV infection: the course and outcome of disease in the apparently immunocompetent is much more…”
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The effects of dopamine and adrenaline infusions on acid-base balance and systemic haemodynamics in severe infection by Day, N P, Phu, N H, Bethell, D P, Mai, N T, Chau, T T, Hien, T T, White, N J

“…Adrenaline is used increasingly in the management of septic shock, but its efficacy and safety are uncertain. In an open, randomised, crossover study we…”
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Combination Antifungal Therapy for Cryptococcal Meningitis by Loyse, Angela, Bicanic, Tihana, Jarvis, Joseph N, Day, Jeremy N, Chau, Tran T.H, Lalloo, David G

“…To the Editor: In the trial of combination therapy for cryptococcal meningitis in patients with human immunodeficiency virus infection, Day et al. (April 4…”
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