Search Results - "Tran, Bang M"
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Renin-Angiotensin Inhibitor, Captopril, Attenuates Growth of Patient-Derived Colorectal Liver Metastasis Organoids
Published in International journal of molecular sciences (01-03-2024)“…The recurrence of colorectal liver metastasis (CRLM) following liver resection is common; approximately 40% of patients will experience tumor recurrence…”
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Captopril, a Renin-Angiotensin System Inhibitor, Attenuates Tumour Progression in the Regenerating Liver Following Partial Hepatectomy
Published in International journal of molecular sciences (09-05-2022)“…(1) Liver regeneration following partial hepatectomy for colorectal liver metastasis (CRLM) has been linked to tumour recurrence. Inhibition of the…”
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Air-Liquid-Interface Differentiated Human Nose Epithelium: A Robust Primary Tissue Culture Model of SARS-CoV-2 Infection
Published in International journal of molecular sciences (13-01-2022)“…The global urgency to uncover medical countermeasures to combat the COVID-19 pandemic caused by the severe acute respiratory syndrome-coronavirus 2…”
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Clinical stage drugs targeting inhibitor of apoptosis proteins purge episomal Hepatitis B viral genome in preclinical models
Published in Cell death & disease (23-06-2021)“…A major unmet clinical need is a therapeutic capable of removing hepatitis B virus (HBV) genome from the liver of infected individuals to reduce their risk of…”
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Isolation and Culture of Adult Intestinal, Gastric, and Liver Organoids for Cre-recombinase-Mediated Gene Deletion
Published in Methods in molecular biology (Clifton, N.J.) (2019)“…The discovery of Lgr5 as a marker of adult stem cells meant that stem cell populations could be purified and studied in isolation. Importantly, when cultured…”
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Uncovering strain- and age-dependent innate immune responses to SARS-CoV-2 infection in air-liquid-interface cultured nasal epithelia
Published in iScience (21-06-2024)“…Continuous assessment of the impact of SARS-CoV-2 on the host at the cell-type level is crucial for understanding key mechanisms involved in host defense…”
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Investigating virus–host cell interactions: Comparative binding forces between hepatitis C virus-like particles and host cell receptors in 2D and 3D cell culture models
Published in Journal of colloid and interface science (15-06-2021)“…[Display omitted] Cell cultures have been successfully used to study hepatitis C virus (HCV) for many years. However, most work has been done using…”
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Assessment of hepatitis B virus infection and interhost cellular responses using intrahepatic cholangiocyte organoids
Published in Journal of medical virology (01-11-2023)“…The intrahepatic cholangiocyte organoids (ICOs) model was evaluated for host differences in hepatitis B virus (HBV) infection, cellular responses, antiviral…”
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Captopril, a Renin-Angiotensin System Inhibitor, Attenuates Features of Tumor Invasion and Down-Regulates C-Myc Expression in a Mouse Model of Colorectal Cancer Liver Metastasis
Published in Cancers (31-05-2021)“…(1) Background: Recent clinical and experimental data suggests that the liver’s regenerative response following partial hepatectomy can stimulate tumor…”
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The Central Role of Wnt Signaling and Organoid Technology in Personalizing Anticancer Therapy
Published in Progress in molecular biology and translational science (01-01-2018)“…The Wnt pathway is at the heart of organoid technology, which is set to revolutionize the cancer field. We can now predetermine a patient's response to any…”
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Development of Matrix-Embedded Bovine Tracheal Organoids to Study the Innate Immune Response against Bovine Respiratory Disease
Published in Organoids (11-05-2023)“…Bovine respiratory disease (BRD) is the leading cause of morbidity and mortality in feedlot cattle. Bovine herpesvirus-1 (BHV-1) is one of the main culprits of…”
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Human Nasal Epithelium Organoids for Assessing Neutralizing Antibodies to a Protective SARS-CoV-2 Virus-like Particle Vaccine
Published in Organoids (01-02-2024)“…Existing mRNA COVID-19 vaccines have shown efficacy in reducing severe cases and fatalities. However, their effectiveness against infection caused by emerging…”
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SAT-179-Human liver organoids culture as a novel in vitro model of HBV infection
Published in Journal of hepatology (01-04-2019)Get full text
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Organoid Models of SARS-CoV-2 Infection: What Have We Learned about COVID-19?
Published in Organoids (02-03-2022)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), which was classified as a pandemic in March 2020. As…”
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