Search Results - "Tracey, K J"
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Cholinergic control of inflammation
Published in Journal of internal medicine (01-06-2009)“… Cytokine production is necessary to protect against pathogens and promote tissue repair, but excessive cytokine release can lead to systemic inflammation,…”
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Journal Article Conference Proceeding -
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Bioelectronic medicine: technology targeting molecular mechanisms for therapy
Published in Journal of internal medicine (01-07-2017)“…Content List – Read more articles from the symposium: 13th Key Symposium – Bioelectronic Medicine: Technology Targeting Molecular Mechanisms…”
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Journal Article -
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The pulse of inflammation: heart rate variability, the cholinergic anti‐inflammatory pathway and implications for therapy
Published in Journal of internal medicine (01-01-2011)“…Huston JM, Tracey KJ (Department of Surgery, Division of General Surgery, Trauma, Surgical Critical Care, and Burns, Stony Brook University Medical Center,…”
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Journal Article Conference Proceeding -
4
Extracellular role of HMGB1 in inflammation and sepsis
Published in Journal of internal medicine (01-03-2004)“… High mobility group box 1 (HMGB1), a 30 kDa nuclear and cytosolic protein widely studied as a transcription factor and growth factor, has recently been…”
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HMGB1 release and redox regulates autophagy and apoptosis in cancer cells
Published in Oncogene (23-09-2010)“…The functional relationship and cross-regulation between autophagy and apoptosis is complex. In this study we show that the high-mobility group box 1 protein…”
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Autonomic neural regulation of immunity
Published in Journal of internal medicine (01-02-2005)“… The ‘cytokine theory of disease’ states that an overproduction of cytokines can cause the clinical manifestations of disease. Much effort has been expended…”
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Journal Article Conference Proceeding -
7
The functions of HMGB1 depend on molecular localization and post-translational modifications
Published in Journal of internal medicine (01-11-2014)Get full text
Journal Article -
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Whole blood cytokine attenuation by cholinergic agonists ex vivo and relationship to vagus nerve activity in rheumatoid arthritis
Published in Journal of internal medicine (01-07-2010)“… Bruchfeld A, Goldstein RS, Chavan S, Patel NB, Rosas‐Ballina M, Kohn N, Qureshi AR, Tracey KJ. (Karolinska Institute, Stockholm, Sweden; The Feinstein…”
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Cholinergic agonists attenuate renal ischemia–reperfusion injury in rats
Published in Kidney international (01-07-2008)“…Inflammation plays a significant role in the pathophysiology of renal ischemia-reperfusion injury. Local inflammation is modulated by the brain via the vagus…”
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High mobility group 1 B‐box mediates activation of human endothelium
Published in Journal of internal medicine (01-10-2003)“…Treutiger CJ, Mullins GE, Johansson A‐SM, Rouhiainen A, Rauvala HME, Erlandsson‐Harris H, Andersson U, Yang H, Tracey KJ, Andersson J, Palmblad JEW (Center for…”
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A novel flexible cuff-like microelectrode for dual purpose, acute and chronic electrical interfacing with the mouse cervical vagus nerve
Published in Journal of neural engineering (01-12-2017)“…Neural reflexes regulate immune responses and homeostasis. Advances in bioelectronic medicine indicate that electrical stimulation of the vagus nerve can be…”
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The haptoglobin beta subunit sequesters HMGB1 toxicity in sterile and infectious inflammation
Published in Journal of internal medicine (01-07-2017)“…Extra-corpuscular haemoglobin is an endogenous factor enhancing inflammatory tissue damage, a process counteracted by the haemoglobin-binding plasma protein…”
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13
Evidence for the involvement of spinal cord glia in subcutaneous formalin induced hyperalgesia in the rat
Published in Pain (Amsterdam) (01-07-1997)“…Subcutaneous (s.c.) injection of formalin induces a rapid and prolonged hyperalgesia across widespread areas of the body. This hyperalgesic state involves a…”
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Expression of Concern: The functions of HMGB1 depend on molecular localization and post‐translational modifications
Published in Journal of internal medicine (01-11-2014)“…This Expression of Concern relates to the article “The functions of HMGB1 depend on molecular localization and post‐translational modifications” by Andersson,…”
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15
Expression of Concern: The haptoglobin beta subunit sequesters HMGB1 toxicity in sterile and infectious inflammation
Published in Journal of internal medicine (01-07-2017)“…Background Extra‐corpuscular haemoglobin is an endogenous factor enhancing inflammatory tissue damage, a process counteracted by the haemoglobin‐binding plasma…”
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HMGB1 mediates splenomegaly and expansion of splenic CD11b+ Ly-6C(high) inflammatory monocytes in murine sepsis survivors
Published in Journal of internal medicine (01-10-2013)“…More than 500,000 hospitalized patients survive severe sepsis annually in the USA. Recent epidemiological evidence, however, demonstrated that these survivors…”
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Neural regulators of innate immune responses and inflammation
Published in Cellular and molecular life sciences : CMLS (01-09-2004)“…The nervous system regulates immune function and inflammation. Experimental evidence shows an important role of the autonomic nervous system in the…”
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Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin
Published in Nature (London) (25-05-2000)“…Vertebrates achieve internal homeostasis during infection or injury by balancing the activities of proinflammatory and anti-inflammatory pathways. Endotoxin…”
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Activation of Human Umbilical Vein Endothelial Cells Leads to Relocation and Release of High‐Mobility Group Box Chromosomal Protein 1
Published in Scandinavian journal of immunology (01-12-2004)“…The nuclear protein high‐mobility group box chromosomal protein 1 (HMGB1) was recently described to act as a pro‐inflammatory cytokine and as a late mediator…”
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HMG-1 as a Late Mediator of Endotoxin Lethality in Mice
Published in Science (American Association for the Advancement of Science) (09-07-1999)“…Endotoxin, a constituent of Gram-negative bacteria, stimulates macrophages to release large quantities of tumor necrosis factor (TNF) and interleukin-1 (IL-1),…”
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