Search Results - "Tracey, Jayne B."

Reversibility of severe metabolic stress in stored platelets after in vitro plasma rescue or in vivo transfusion: restoration of secretory function and maintenance of platelet survival by Rinder, Henry M., Snyder, Edward L., Tracey, Jayne B., Dincecco, Dorothy, Wang, Chao, Baril, Laurence, Rinder, Christine S., Smith, Brian R.

“…BACKGROUND:  Determining reversible aspects of the platelet storage lesion may result in improved function and survival of transfused platelets. STUDY DESIGN…”
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Effects of Meloxicam on Platelet Function in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Trial by Rinder, Henry M., Tracey, Jayne B., Souhrada, Magdalena, Wang, Chao, Gagnier, R. Paul, Wood, Chester C.

“…Nonsteroidal anti‐inflammatory drugs (NSAIDs) inhibit cyclooxygenase‐1 (COX‐1), thereby inhibiting platelet function via blockade of thromboxane A2 (TxA2)…”
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Antithrombin reduces monocyte and neutrophil CD11b up regulation in addition to blocking platelet activation during extracorporeal circulation by Rinder, Christine S., Rinder, Henry M., Smith, Michael J., Fitch, Jane C.K., Tracey, Jayne B., Chandler, Wayne L., Rollins, Scott A., Smith, Brian R.

“…BACKGROUND:  Patients undergoing cardiac surgery requiring cardiopulmonary bypass develop a systemic inflammatory reaction. Antithrombin III (AT) has…”
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The Effects of Heparin, Protamine, and Heparin/Protamine Reversal on Platelet Function Under Conditions of Arterial Shear Stress by Griffin, Michael J., Rinder, Henry M., Smith, Brian R., Tracey, Jayne B., Kriz, Nancy S., Li, Conan K., Rinder, Christine S.

“…Platelet dysfunction contributes to blood loss after cardiopulmonary bypass. This study examined the antiplatelet effects of heparin, protamine, and varying…”
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Xenotransplantation of immunodeficient mice with mobilized human blood CD34+ cells provides an in vivo model for human megakaryocytopoiesis and platelet production by Perez, Lia E., Rinder, Henry M., Wang, Chao, Tracey, Jayne B., Maun, Noel, Krause, Diane S.

“…The study of megakaryocytopoiesis has been based largely on in vitro assays. We characterize an in vivo model of megakaryocyte and platelet development in…”
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Selective blockade of membrane attack complex formation during simulated extracorporeal circulation inhibits platelet but not leukocyte activation by Rinder, Christine S., Rinder, Henry M., Smith, Michael J., Tracey, Jayne B., Fitch, Jane, Li, Lan, Rollins, Scott A., Smith, Brian R.

“…Objective: Complement activation is induced by cardiopulmonary bypass, and previous work found that late complement components (C5a, C5b-9) contribute to…”
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Acadesine inhibits neutrophil CD11b up-regulation in vitro and during in vivo cardiopulmonary bypass by Mathew, Joseph P., Rinder, Christine S., Tracey, Jayne B., Auszura, Laura A., O'Connor, Theresa, Davis, Elizabeth, Smith, Brian R.

“…Granulocyte adhesion to ischemic tissue, mediated in large part by β 2 integrin receptors, is important in the pathophysiology of reperfusion injury…”
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Nitroprusside inhibition of platelet function is transient and reversible by catecholamine priming by HARRIS, S. N, RINDER, C. S, RINDER, H. M, TRACEY, J. B, SMITH, B. R, HINES, R

“…The time course and reversibility of sodium nitroprusside's in vivo inhibition of platelet function are unclear. Platelet aggregation and P-selectin expression…”
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Blockade of C5a and C5b-9 generation inhibits leukocyte and platelet activation during extracorporeal circulation by Rinder, C S, Rinder, H M, Smith, B R, Fitch, J C, Smith, M J, Tracey, J B, Matis, L A, Squinto, S P, Rollins, S A

“…Complement activation contributes to the systemic inflammatory response induced by cardiopulmonary bypass. At the cellular level, cardiopulmonary bypass…”
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TRANSFUSION PRACTICE: Antithrombin reduces monocyte and neutrophil CD11b up regulation in addition to blocking platelet activation during extracorporeal circulation by Rinder, Christine S, Rinder, Henry M, Smith, Michael J, Fitch, Jane CK, Tracey, Jayne B, Chandler, Wayne L, Rollins, Scott A, Smith, Brian R

“…BACKGROUND:Patients undergoing cardiac surgery requiring cardiopulmonary bypass develop a systemic inflammatory reaction. Antithrombin III (AT) has…”
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Differences in platelet alpha-granule release between normals and immune thrombocytopenic patients and between young and old platelets by Rinder, H M, Tracey, J B, Recht, M, DeCastro, L, Rinder, C S, McHugh, C, Smith, B R

“…The risk of serious bleeding in patients with immune thrombocytopenic purpura (ITP) appears to be less than in comparably thrombocytopenic patients with…”
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Lymphocyte and monocyte subset changes during cardiopulmonary bypass: Effects of aging and gender by Rinder, Christine S., Mathew, Joseph P., Rinder, Henry M., Tracey, Jayne B., Davis, Elizabeth, Smith, Brian R.

“…Complications of cardiopulmonary bypass (CPB) may be associated with either immune suppression or immune activation, but the specific effects of CPB on many…”
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