Search Results - "Trémeau, Odile"

Genetic engineering of snake toxins. The functional site of Erabutoxin a, as delineated by site-directed mutagenesis, includes variant residues by Trémeau, O, Lemaire, C, Drevet, P, Pinkasfeld, S, Ducancel, F, Boulain, J C, Ménez, A

“…Using site-directed mutagenesis, we previously identified some residues that probably belong to the site by which Erabutoxin a (Ea), a sea snake toxin,…”
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Genetic engineering of snake toxins. Role of invariant residues in the structural and functional properties of a curaremimetic toxin, as probed by site-directed mutagenesis by PILLET, L, TREMEAU, O, DUCANTEL, F, DREVET, P, ZINN-JUSTIN, S, PINKASFELD, S, BOULAIN, J.-C, MENEZ, A

“…To study the site by which erabutoxin a (Ea) from Laticauda semifasciata binds to the nicotinic acetylcholine receptor, we mutated most residues that are…”
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Mimicry between receptors and antibodies. Identification of snake toxin determinants recognized by the acetylcholine receptor and an acetylcholine receptor-mimicking monoclonal antibody by Ducancel, F, Mérienne, K, Fromen-Romano, C, Trémeau, O, Pillet, L, Drevet, P, Zinn-Justin, S, Boulain, J C, Ménez, A

“…In several instances, a monoclonal antibody raised against a receptor ligand has been claimed to mimic the ligand receptor. Thus, a specific monoclonal…”
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Mimicry between Receptors and Antibodies by Ducancel, Frédéric, Mérienne, Karine, Fromen-Romano, Cécile, Trémeau, Odile, Pillet, Laurence, Drevet, Pascal, Zinn-Justin, Sophie, Boulain, Jean-Claude, Ménez, André

“…In several instances, a monoclonal antibody raised against a receptor ligand has been claimed to mimic the ligand receptor. Thus, a specific monoclonal…”
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Genetic Engineering of Snake Toxins by Trémeau, Odile, Lemaire, Caroline, Drevet, Pascal, Pinkasfeld, Suzanne, Ducancel, Frédéric, Boulain, Jean-Claude, Ménez, André

“…Using site-directed mutagenesis, we previously identified some residues that probably belong to the site by which Erabutoxin a (Ea), a sea snake toxin,…”
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A monoclonal antibody which recognized the functional site of snake neurotoxins and which neutralizes all short-chain variants by Trémeau, Odile, Boulain, Jean-Claude, Couderc, Jacques, Fromageot, Pierre, Ménez, André

“…We isolated a neurotoxin-specific monoclonal antibody (Mab) which is capable of recognizing and neutralizing all short-chain toxin variants that have been…”
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Role and environment of the conserved Lys27 of snake curaremimetic toxins as probed by chemical modifications, site‐directed mutagenesis and photolabelling experiments by HERVÉ, Mireille, PILLET, Laurence, HUMBERT, Paul, TRÉMEAU, Odile, DUCANCEL, Frédéric, HIRTH, Christian, MÉNEZ, André

“…The positive charge of Lys27 was supressed by chemical means in two short‐chain curaremimetic toxins, namely erabutoxin a (Ea) from Laticauda semifasciata and…”
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Notechis 11′2, a non‐toxic phospholipase A 2 from the venom of Notechis scutatus scutatus by BOUCHIER, Christiane, BOYOT, Philippe, TESSON, Frédérique, TRÉMEAU, Odile, BOUET, Françoise, HODGSON, Darren, BOULAIN, Jean‐Claude, MÉNEZ, André

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Notechis 11′2, a non‐toxic phospholipase A2 from the venom of Notechis scutatus scutatus by BOUCHIER, Christiane, BOYOT, Philippe, TESSON, Frédérique, TRÉMEAU, Odile, BOUET, Françoise, HODGSON, Darren, BOULAIN, Jean‐Claude, MÉNEZ, André

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Notechis 11′2, a non‐toxic phospholipase A 2 from the venom of Notechis scutatus scutatus by BOUCHIER, Christiane, BOYOT, Philippe, TESSON, Frédérique, TRÉMEAU, Odile, BOUET, Françoise, HODGSON, Darren, BOULAIN, Jean‐Claude, MÉNEZ, André

“…Previously, we deduced the amino acid sequence of a novel phospholipase‐A 2 ‐like protein (PLA 2 ) from the nucleotide sequence of a cDNA isolated from a…”
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Notechis 11′2, a non‐toxic phospholipase A2 from the venom of Notechis scutatus scutatus by BOUCHIER, Christiane, BOYOT, Philippe, TESSON, Frédérique, TRÉMEAU, Odile, BOUET, Françoise, HODGSON, Darren, BOULAIN, Jean‐Claude, MÉNEZ, André

“…Previously, we deduced the amino acid sequence of a novel phospholipase‐A2‐like protein (PLA2) from the nucleotide sequence of a cDNA isolated from a library…”
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A recombinant snake neurotoxin generated by chemical cleavage of a hybrid protein recovers full biological properties by Boyot, Philippe, Pillet, Laurence, Ducancel, Frédéric, Boulain, Jean-Claude, Tremeau, Odile, Ménez, André

“…We previously reported the production of a fused snake neurotoxin composed of protein A and erabutoxin a in E. coli [1]. The hybrid had much lower toxicity and…”
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