Search Results - "Toyota, Tokuko"
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iPSC-Derived Neoantigen-Specific CTL Therapy for Ewing Sarcoma
Published in Cancer immunology research (01-10-2021)“…The prognosis of Ewing sarcoma caused by fusion is poor, especially after metastasis. Although therapy with CTLs targeted against altered EWS/FLI1 sequences at…”
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Dasatinib-induced anti-leukemia cellular immunity through a novel subset of CD57 positive helper/cytotoxic CD4 T cells in chronic myelogenous leukemia patients
Published in International journal of hematology (01-12-2018)“…Dasatinib induces lymphocytosis of large granular lymphocytes (LGLs) in a proportion of patients with chronic myelogenous leukemia (CML), and is associated…”
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Establishment of ganglioside GD2-expressing extranodal NK/T-cell lymphoma cell line with scRNA-seq analysis
Published in Experimental hematology (01-02-2024)“…•A novel GD2+ extranodal NK/T-cell lymphoma cell line, ENKL-J1, was established.•GD2-CART cells exhibited robust cytotoxicity for ENKL-J1 cells in vitro and in…”
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Dual-antigen targeted iPSC-derived chimeric antigen receptor-T cell therapy for refractory lymphoma
Published in Molecular therapy (02-02-2022)“…We generated dual-antigen receptor (DR) T cells from induced pluripotent stem cells (iPSCs) to mitigate tumor antigen escape. These cells were engineered to…”
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Sustainable Tumor-Suppressive Effect of iPSC-Derived Rejuvenated T Cells Targeting Cervical Cancers
Published in Molecular therapy (04-11-2020)“…Immunotherapy utilizing induced pluripotent stem cell (iPSC) technology has great potential. Functionally rejuvenated cytotoxic T lymphocytes (CTLs) can…”
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iPSC-derived hypoimmunogenic tissue resident memory T cells mediate robust anti-tumor activity against cervical cancer
Published in Cell reports. Medicine (19-12-2023)“…Functionally rejuvenated human papilloma virus-specific cytotoxic T lymphocytes (HPV-rejTs) generated from induced pluripotent stem cells robustly suppress…”
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