Search Results - "Toyooka, Kiyomi O"

Aberrant Promoter Methylation Profile of Prostate Cancers and Its Relationship to Clinicopathological Features by MARUYAMA, Riichiroh, TOYOOKA, Shinichi, TOYOOKA, Kiyomi O, VIRMANI, Arvind K, ZÖCHBAUER-MÜLLER, Sabine, FARINAS, Alfredo J, MINNA, John D, MCCONNELL, John, FRENKEL, Eugene P, GAZDAR, Adi F

“…Purpose: We investigated the aberrant methylation profile of prostate cancers and correlated the data with clinical findings. Experimental Design: Gene…”
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Promoter Hypermethylation Profile of Ovarian Epithelial Neoplasms by MAKARLA, Prakash B, SABOORIAN, M. Hossein, ASHFAQ, Raheela, TOYOOKA, Kiyomi O, TOYOOKA, Shinichi, MINNA, John D, GAZDAR, Adi F, SCHORGE, John O

“…Purpose: Ovarian carcinomas are believed to arise de novo from surface epithelium, but the actual molecular pathogenesis is unknown. The aim of this study was…”
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Smoke exposure, histologic type and geography‐related differences in the methylation profiles of non‐small cell lung cancer by Toyooka, Shinichi, Maruyama, Riichiroh, Toyooka, Kiyomi O., McLerran, Dale, Feng, Ziding, Fukuyama, Yasuro, Virmani, Arvind K., Zochbauer‐Muller, Sabine, Tsukuda, Kazunori, Sugio, Kenji, Shimizu, Nobuyoshi, Shimizu, Kenji, Lee, Huei, Chen, Chih‐Yi, Fong, Kwun M., Gilcrease, Michael, Roth, Jack A., Minna, John D., Gazdar, Adi F.

“…Aberrant methylation of several known or putative tumor suppressor genes occurs frequently during the pathogenesis of lung cancers. There are major smoke…”
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Aberrant methylation of trail decoy receptor genes is frequent in multiple tumor types by Shivapurkar, Narayan, Toyooka, Shinichi, Toyooka, Kiyomi O., Reddy, Jyotsna, Miyajima, Kuniharu, Suzuki, Makoto, Shigematsu, Hisayuki, Takahashi, Takao, Parikh, Gunjan, Pass, Harvey I., Chaudhary, Preet M., Gazdar, Adi F.

“…TNF‐related apoptosis‐inducing ligand (TRAIL) selectively induces programmed cell death (apoptosis) in various cancer cells but not in normal cells. TRAIL is…”
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Aberrant methylation of multiple genes in the upper aerodigestive tract epithelium of heavy smokers by Zöchbauer‐Müller, Sabine, Lam, Stephen, Toyooka, Shinichi, Virmani, Arvind K., Toyooka, Kiyomi O., Seidl, Sonja, Minna, John D., Gazdar, Adi F.

“…An important method for silencing tumor suppressor genes in cancers is by aberrant methylation (referred to as methylation) of CpG islands in gene promoter…”
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Aberrant promoter methylation and silencing of the RASSF1A gene in pediatric tumors and cell lines by HARADA, Kenichi, TOYOOKA, Shinichi, GAZDAR, Adi F, MAITRA, Anirban, MARUYAMA, Riichiroh, TOYOOKA, Kiyomi O, TIMMONS, Charles F, TOMLINSON, Gail E, MASTRANGELO, Domenico, HAY, Robert J, MINNA, John D

“…Aberrant promoter methylation of tumor suppressor genes has not been fully investigated in pediatric tumors. Therefore, we examined the methylation status of…”
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Epigenetic Down-Regulation of Death-associated Protein Kinase in Lung Cancers by Toyooka, Shinichi, Toyooka, Kiyomi O, Miyajima, Kuniharu, Reddy, Jyotsna L, Toyota, Minoru, Sathyanarayana, Ubradka G, Padar, Asha, Tockman, Melvyn S, Lam, Stephen, Shivapurkar, Narayan, Gazdar, Adi F

“…Purpose: Death-associated protein kinase ( DAPK ) is a pro-apoptotic serine/threonine kinase involved in apoptosis. Aberrant methylation of DAPK was reported…”
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Progressive aberrant methylation of the RASSF1A gene in simian virus 40 infected human mesothelial cells by TOYOOKA, Shinichi, CARBONE, Michele, TOYOOKA, Kiyomi O, BOCCHETTA, Maurizio, SHIVAPURKAR, Narayan, MINNA, John D, GAZDAR, Adi F

“…Mesotheliomas are tumors arising from mesothelial cells and are associated with asbestos exposure and approximately 50% contain simian virus 40 (SV40) DNA…”
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Aberrant promoter methylation profile of bladder cancer and its relationship to clinicopathological features by MARUYAMA, Riichiroh, TOYOOKA, Shinichi, CZERNIAK, Bogdan, GAZDAR, Adi F, TOYOOKA, Kiyomi O, HARADA, Kenichi, VIRMANI, Arvind K, ZÖCHBAUER-MÜLLER, Sabine, FARINAS, Alfredo J, VAKAR-LOPEZ, Funda, MINNA, John D, SAGALOWSKY, Arthur

“…We investigated the aberrant promoter methylation profile of bladder cancers and correlated the data with clinicopathological findings. The methylation status…”
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Loss of expression and aberrant methylation of the CDH13 (H-cadherin) gene in breast and lung carcinomas by TOYOOKA, Kiyomi O, TOYOOKA, Shinichi, VIRMANI, Arvind K, SATHYANARAYANA, Ubaradka G, EUHUS, David M, GILCREASE, Michael, MINNA, John D, GAZDAR, Adi F

“…Expression of some members of the cadherin family is reduced in several human tumors, and CDH13 (H-cadherin), located on chromosome 16q24.2-3, may function as…”
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Aberrant methylation of the CDH13 (H-cadherin) promoter region in colorectal cancers and adenomas by TOYOOKA, Shinichi, TOYOOKA, Kiyomi O, GAZDAR, Adi F, HARADA, Kenichi, MIYAJIMA, Kuniharu, MAKARLA, Prakash, SATHYANARAYANA, Ubaradka G, YIN, Jing, SATO, Fumiaki, SHIVAPURKAR, Narayan, MELTZER, Stephen J

“…Expression of the cadherin family member CDH13 (H-cadherin) is reduced in several human tumors, and it has been hypothesized that this gene functions as a…”
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Aberrant methylation and simian virus 40 tag sequences in malignant mesothelioma by TOYOOKA, Shinichi, PASS, Harvey I, SHIVAPURKAR, Narayan, FUKUYAMA, Yasuro, MARUYAMA, Riichiroh, TOYOOKA, Kiyomi O, GILCREASE, Michael, FARINAS, Alfredo, MINNA, John D, GAZDAR, Adi F

“…Aberrant promoter methylation and resultant silencing of several genes plays an important role in the pathogenesis of many tumor types. We compared the…”
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Dose effect of smoking on aberrant methylation in non‐small cell lung cancers by Toyooka, Shinichi, Suzuki, Makoto, Tsuda, Toshihide, Toyooka, Kiyomi O., Maruyama, Riichiroh, Tsukuda, Kazunori, Fukuyama, Yasuro, Iizasa, Toshihiko, Fujisawa, Takehiko, Shimizu, Nobuyoshi, Minna, John D., Gazdar, Adi F.

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Establishment and Validation of Real-Time Polymerase Chain Reaction Method for CDH1 Promoter Methylation by Toyooka, Kiyomi O., Toyooka, Shinichi, Maitra, Anirban, Feng, Qinghua, Kiviat, Nancy C., Smith, Alice, Minna, John D., Ashfaq, Raheela, Gazdar, Adi F.

“…Aberrant methylation of the promoter region has emerged as the major mechanism for silencing tumor suppressor genes. However, for some genes, such as…”
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DNA methylation profiles of lung tumors by Toyooka, S, Toyooka, K O, Maruyama, R, Virmani, A K, Girard, L, Miyajima, K, Harada, K, Ariyoshi, Y, Takahashi, T, Sugio, K, Brambilla, E, Gilcrease, M, Minna, J D, Gazdar, A F

“…Aberrant methylation of CpG islands in promoter regions of tumor cells is one of the major mechanisms for silencing of tumor suppressor genes. We determined…”
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Establishment and Validation of Quantitative Real-time PCR Assay for Aberrant Methylation of 14-3-3σ Gene in Breast and Lung Carcinoma by UBARADKA G. SATHYANARAYANA MAKOTO SUZUKI SHINICHI TOYOOKA ASHA PADAR KIYOMI O. TOYOOKA ANDREA L. ZERN KUNIHARU MIYAJIMA TAKASHI TAKAHASHI ELIZABETH BRAMBILLA ADI F. GAZDAR

“…Background: 14-3-3σ gene has been shown to be responsible for G2 cell cycle checkpoint control by p53 in response to DNA damage in human cells. In order to…”
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Cancer patients undergoing chemotherapy show adequate serological response to vaccinations against influenza virus and Streptococcus pneumoniae by Nordøy, Tone, Aaberge, Ingeborg S, Husebekk, Anne, Samdal, Helvi H, Steinert, Svein, Melby, Hasse, Kolstad, Arne

“…Cancer patients receiving chemotherapy are prone to develop infections that might postpone treatment and lead to complications. The aim of our study was to…”
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Progressive aberrant methylation of the RASSF1Agene in simian virus 40 infected human mesothelial cells by Toyooka, Shinichi, Carbone, Michele, Toyooka, Kiyomi O, Bocchetta, Maurizio, Shivapurkar, Narayan, Minna, John D, Gazdar, Adi F

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Epigenetic down-regulation of death-associated protein kinase in lung cancer by TOYOOKA, Shinichi, TOYOOKA, Kiyomi O, GAZDAR, Adi F, MIYAJIMA, Kuniharu, REDDY, Jyotsna L, TOYOTA, Minoru, SATHYANARAYANA, Ubradka G, PADAR, Asha, TOCKMAN, Melvyn S, LAM, Stephen, SHIVAPURKAR, Narayan

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P-309 Aberrant methylation of the tumor necrosis factor related apoptosis inducing ligand decoy receptor genes in malignant mesothelioma and lung cancer by Toyooka, Shinichi, Shivapurkar, Narayan, Toyooka, Kiyomi O., Miyajima, Kuniharu, Suzuki, Makoto, Redd, Jyotsna, Pass, Harvey I., Roth, Jack A., Minna, John D., Gazdar, Adi F.

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