Search Results - "Toyokawa, Gouji"

Weakly-supervised learning for lung carcinoma classification using deep learning by Kanavati, Fahdi, Toyokawa, Gouji, Momosaki, Seiya, Rambeau, Michael, Kozuma, Yuka, Shoji, Fumihiro, Yamazaki, Koji, Takeo, Sadanori, Iizuka, Osamu, Tsuneki, Masayuki

“…Lung cancer is one of the major causes of cancer-related deaths in many countries around the world, and its histopathological diagnosis is crucial for deciding…”
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Significance of Spread Through Air Spaces in Resected Pathological Stage I Lung Adenocarcinoma by Toyokawa, Gouji, Yamada, Yuichi, Tagawa, Tetsuzo, Kozuma, Yuka, Matsubara, Taichi, Haratake, Naoki, Takamori, Shinkichi, Akamine, Takaki, Oda, Yoshinao, Maehara, Yoshihiko

“…“Spread through air spaces” (STAS) is a recently described invasive pattern of lung cancer that spreads within air spaces beyond the edge of the main tumor. In…”
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A deep learning model for the classification of indeterminate lung carcinoma in biopsy whole slide images by Kanavati, Fahdi, Toyokawa, Gouji, Momosaki, Seiya, Takeoka, Hiroaki, Okamoto, Masaki, Yamazaki, Koji, Takeo, Sadanori, Iizuka, Osamu, Tsuneki, Masayuki

“…The differentiation between major histological types of lung cancer, such as adenocarcinoma (ADC), squamous cell carcinoma (SCC), and small-cell lung cancer…”
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Crizotinib can overcome acquired resistance to CH5424802: is amplification of the MET gene a key factor? by Gouji, Toyokawa, Takashi, Seto, Mitsuhiro, Takenoyama, Yukito, Ichinose

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Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker by Takawa, Masashi, Masuda, Ken, Kunizaki, Masaki, Daigo, Yataro, Takagi, Katsunori, Iwai, Yukiko, Cho, Hyun‐Soo, Toyokawa, Gouji, Yamane, Yuka, Maejima, Kazuhiro, Field, Helen I., Kobayashi, Takaaki, Akasu, Takayuki, Sugiyama, Masanori, Tsuchiya, Eijyu, Atomi, Yutaka, Ponder, Bruce A. J., Nakamura, Yusuke, Hamamoto, Ryuji

“…The emphasis in anticancer drug discovery has always been on finding a drug with great antitumor potential but few side‐effects. This can be achieved if the…”
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Clinical Significance of PD-L1 Protein Expression in Surgically Resected Primary Lung Adenocarcinoma by Takada, Kazuki, Okamoto, Tatsuro, Shoji, Fumihiro, Shimokawa, Mototsugu, Akamine, Takaki, Takamori, Shinkichi, Katsura, Masakazu, Suzuki, Yuzo, Fujishita, Takatoshi, Toyokawa, Gouji, Morodomi, Yosuke, Okano, Shinji, Oda, Yoshinao, Maehara, Yoshihiko

“…The clinicopathological features of carcinomas expressing programmed death ligand 1 (PD-L1) and their associations with common driver mutations, such as…”
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The Significance of the PD-L1 Expression in Non–Small-Cell Lung Cancer: Trenchant Double Swords as Predictive and Prognostic Markers by Takada, Kazuki, Toyokawa, Gouji, Shoji, Fumihiro, Okamoto, Tatsuro, Maehara, Yoshihiko

“…Lung cancer is the leading cause of death due to cancer worldwide. Surgery, chemotherapy, and radiotherapy have been the standard treatment for lung cancer,…”
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Combination Therapy of Radiotherapy and Anti-PD-1/PD-L1 Treatment in Non–Small-cell Lung Cancer: A Mini-review by Takamori, Shinkichi, Toyokawa, Gouji, Takada, Kazuki, Shoji, Fumihiro, Okamoto, Tatsuro, Maehara, Yoshihiko

“…Immune checkpoint inhibitors against programmed cell death-1 (PD-1) or programmed cell death-ligand 1 (PD-L1) are a standard pharmacologic therapy for patients…”
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Spotlight on lorlatinib and its potential in the treatment of NSCLC: the evidence to date by Akamine, Takaki, Toyokawa, Gouji, Tagawa, Tetsuzo, Seto, Takashi

“…The identification of anaplastic lymphoma kinase ( ), an oncogenetic driver mutation, in lung cancer has paved the way for a new era in the treatment of…”
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Correlation between CXCR4/CXCR7/CXCL12 chemokine axis expression and prognosis in lymph‐node‐positive lung cancer patients by Katsura, Masakazu, Shoji, Fumihiro, Okamoto, Tatsuro, Shimamatsu, Shinichiro, Hirai, Fumihiko, Toyokawa, Gouji, Morodomi, Yosuke, Tagawa, Tetsuzo, Oda, Yoshinao, Maehara, Yoshihiko

“…The CXCR4/CXCR7/CXCL12 chemokine axis plays important roles in the migration of tumor cells during cancer development by modulating site‐specific distant…”
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Complete Blood Cell Count-Derived Inflammatory Biomarkers in Early-Stage Non-Small-Cell Lung Cancer by Shoji, Fumihiro, Kozuma, Yuka, Toyokawa, Gouji, Yamazaki, Koji, Takeo, Sadanori

“…Background: Complete blood cell count (CBC)-derived inflammatory biomarkers are widely used as prognostic parameters for various malignancies, but the best…”
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Significance of spread through air spaces in early‐stage lung adenocarcinomas undergoing limited resection by Toyokawa, Gouji, Yamada, Yuichi, Tagawa, Tetsuzo, Oda, Yoshinao

“…Background In early‐stage lung adenocarcinomas, spread through air spaces (STAS) are reported to be a prognostic factor in patients who have undergone sublobar…”
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Clinical impact of skeletal muscle area in patients with non-small cell lung cancer treated with anti-PD-1 inhibitors by Takada, Kazuki, Yoneshima, Yasuto, Tanaka, Kentaro, Okamoto, Isamu, Shimokawa, Mototsugu, Wakasu, Sho, Takamori, Shinkichi, Toyokawa, Gouji, Oba, Taro, Osoegawa, Atsushi, Tagawa, Tetsuzo, Oda, Yoshinao, Nakanishi, Yoichi, Mori, Masaki

“…Purpose The aim of this study was to elucidate the clinical impact of skeletal muscle area (SMA) in patients with non-small cell lung cancer (NSCLC) treated…”
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Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers by Yoshimatsu, Masanori, Toyokawa, Gouji, Hayami, Shinya, Unoki, Motoko, Tsunoda, Tatsuhiko, Field, Helen I., Kelly, John D., Neal, David E., Maehara, Yoshihiko, Ponder, Bruce A.J., Nakamura, Yusuke, Hamamoto, Ryuji

“…Protein arginine methylation is a novel post‐translational modification regulating a diversity of cellular processes, including histone functions, but the…”
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PD-L1 expression according to the EGFR status in primary lung adenocarcinoma by Takada, Kazuki, Toyokawa, Gouji, Tagawa, Tetsuzo, Kohashi, Kenichi, Shimokawa, Mototsugu, Akamine, Takaki, Takamori, Shinkichi, Hirai, Fumihiko, Shoji, Fumihiro, Okamoto, Tatsuro, Oda, Yoshinao, Maehara, Yoshihiko

“…•Association between PD-L1 expression and EGFR mutation site is poorly reported.•We investigated the association between PD-L1 expression and EGFR…”
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The Expression of PD-L1 Protein as a Prognostic Factor in Lung Squamous Cell Carcinoma by Takada, Kazuki, Okamoto, Tatsuro, Toyokawa, Gouji, Kozuma, Yuka, Matsubara, Taichi, Haratake, Naoki, Akamine, Takaki, Takamori, Shinkichi, Katsura, Masakazu, Shoji, Fumihiro, Oda, Yoshinao, Maehara, Yoshihiko

“…Highlights • The significance of PD-L1 expression in SCC patients remains unclear. • The expression was evaluated with four different cut-off values in this…”
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A Positive Correlation Between the EZH2 and PD-L1 Expression in Resected Lung Adenocarcinomas by Toyokawa, Gouji, Takada, Kazuki, Tagawa, Tetsuzo, Hamamoto, Ryuji, Yamada, Yuichi, Shimokawa, Mototsugu, Oda, Yoshinao, Maehara, Yoshihiko

“…Enhancer of zeste homolog 2 (EZH2) is reported to be involved in lung cancer pathogenesis via the epigenetic regulation of various genes. Recently, EZH2 was…”
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A Clinicopathological and Prognostic Analysis of PD-L2 Expression in Surgically Resected Primary Lung Squamous Cell Carcinoma by Matsubara, Taichi, Takada, Kazuki, Azuma, Koichi, Takamori, Shinkichi, Toyokawa, Gouji, Haro, Akira, Osoegawa, Atsushi, Tagawa, Tetsuzo, Kawahara, Akihiko, Akiba, Jun, Okamoto, Isamu, Nakanishi, Yoichi, Oda, Yoshinao, Hoshino, Tomoaki, Maehara, Yoshihiko

“…Background Immunotherapy targeting programmed cell death-1 (PD-1) and programmed death-ligand 1 (PD-L1) has shown dramatic therapeutic effects for lung…”
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Clinical implications of the novel cytokine IL-38 expressed in lung adenocarcinoma: Possible association with PD-L1 expression by Takada, Kazuki, Okamoto, Tatsuro, Tominaga, Masaki, Teraishi, Koji, Akamine, Takaki, Takamori, Shinkichi, Katsura, Masakazu, Toyokawa, Gouji, Shoji, Fumihiro, Okamoto, Masaki, Oda, Yoshinao, Hoshino, Tomoaki, Maehara, Yoshihiko

“…Interleukin (IL)-38, a novel member of the IL-1 cytokine family, is homologous to IL-1 receptor antagonist (IL-1Ra) and IL-36Ra, and has been reported to act…”
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IgG4-Related Lung Disease Exhibiting the Invasion into the Diaphragm: A Case Report by Ono, Yuki, Toyokawa, Gouji, Tagawa, Tetsuzo, Ijichi, Kayo, Oda, Yoshinao, Mori, Masaki

“…Immunoglobulin G4-related disease (IgG4-RD) is a fibroinflammatory condition which involves various organs. This is a very rare case of IgG4-related lung…”
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