Search Results - "Toyka, K V"

Elevated proinflammatory cytokine expression in affected skin in small fiber neuropathy by ÜCEYLER, N, KAFKE, W, RIEDIGER, N, HE, L, NECULA, G, TOYKA, K. V, SOMMER, C

“…Small fiber neuropathy (SFN) is a subtype of sensory neuropathy with acral pain and normal findings in routine nerve conduction studies. Twenty-four patients…”
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Fatigue in multiple sclerosis: a comparison of different rating scales and correlation to clinical parameters by Flachenecker, P, Kümpfel, T, Kallmann, B, Gottschalk, M, Grauer, O, Rieckmann, P, Trenkwalder, C, Toyka, K V

“…Objectives: Fatigue is one of the most common, yet poorly defined, disabling symptoms in patients with multiple sclerosis (MS). To delineate more clearly the…”
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Fatal PML associated with efalizumab therapy: Insights into integrin αLβ2 in JC virus control by SCHWAB, N, ULZHEIMER, J. C, BRÜCK, W, TOYKA, K. V, RANSOHOFF, R. M, WIENDL, H, FOX, R. J, SCHNEIDER-HOHENDORF, T, KIESEIER, B. C, MONORANU, C. M, STAUGAITIS, S. M, WELCH, W, JILEK, S, DU PASQUIER, R. A

“…Progressive multifocal leukoencephalopathy (PML) has become much more common with monoclonal antibody treatment for multiple sclerosis and other…”
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Macrophage clustering as a diagnostic marker in sural nerve biopsies of patients with CIDP by SOMMER, C, KOCH, S, LAMMENS, M, GABREELS-FESTEN, A, STOLL, G, TOYKA, K. V

“…In adult patients with a slowly progressive demyelinating neuropathy, it may be difficult to distinguish between a hereditary neuropathy and chronic…”
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Rapid-onset central motor plasticity in multiple sclerosis by ZELLER, D, AUFM KAMPE, K, CLASSEN, J, BILLER, A, STEFAN, K, GENTNER, R, SCHÜTZ, A, BARTSCH, A, BENDSZUS, M, TOYKA, K. V, RIECKMANN, P

“…To study rapid-onset central motor plasticity, and its relationship to motor impairment and CNS injury in patients with multiple sclerosis (MS). In this…”
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Increased autophagy in peripheral nerves may protect Wistar Ottawa Karlsburg W rats against neuropathy by Kosacka, J., Nowicki, M., Blüher, M., Baum, P., Stockinger, M., Toyka, K.V., Klöting, I., Stumvoll, M., Serke, H., Bechmann, I., Klöting, N.

“…Wistar Ottawa Karlsburg W (RT1u) rats (WOKW) develop obesity, dyslipidemia, moderate hypertension, hyperinsulinemia and impaired glucose tolerance prone to…”
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Symptomatic treatment of multiple sclerosis. Multiple Sclerosis Therapy Consensus Group (MSTCG) of the German Multiple Sclerosis Society by Henze, T, Rieckmann, P, Toyka, K V

“…Besides immunomodulation and immunosuppression, the specific treatment of symptoms is an essential component of the overall management of multiple sclerosis…”
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Early abnormalities of evoked potentials and future disability in patients with multiple sclerosis by Kallmann, B A, Fackelmann, S, Toyka, K V, Rieckmann, P, Reiners, K

“…Evoked potentials (EP) have a role in making the diagnosis of multiple sclerosis (MS) but their implication for predicting the future disease course in MS is…”
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Preceding infections, immune factors, and outcome in Guillain-Barré syndrome by HADDEN, R. D. M, KARCH, H, TOYKA, K. V, HARTUNG, H.-P, ZIELASEK, J, WEISSBRICH, B, SCHUBERT, J, WEISHAUPT, A, CORNBLATH, D. R, SWAN, A. V, HUGHES, R. A. C

“…To test the hypothesis that different preceding infections influence the neurophysiologic classification and clinical features of Guillain-Barré syndrome…”
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Mitoxantrone induces cell death in peripheral blood leucocytes of multiple sclerosis patients by Chan, A., Weilbach, F. X., Toyka, K. V., Gold, R.

“…Summary Mitoxantrone (MX) is a cytotoxic drug with proven clinical efficacy in active multiple sclerosis (MS). In this ex vivo study we investigated the…”
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Disease progression in amyotrophic lateral sclerosis: Predictors of survival by Magnus, T., Beck, M., Giess, R., Puls, I., Naumann, M., Toyka, K.V.

“…Predicting the rate of disease progression has become important as trials of new medical treatments for amyotrophic lateral sclerosis (ALS) are planned. Bulbar…”
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Fatigue in MS is related to sympathetic vasomotor dysfunction by FLACHENECKER, P, RUFER, A, BIHLER, I, HIPPEL, C, REINERS, K, TOYKA, K. V, KESSELRING, J

“…The authors studied standard autonomic function tests and measures of heart rate variability in 60 patients with multiple sclerosis (MS) and correlated results…”
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Injections of botulinum toxin A into the salivary glands improve sialorrhoea in amyotrophic lateral sclerosis by Giess, R, Naumann, M, Werner, E, Riemann, R, Beck, M, Puls, I, Reiners, C, Toyka, K V

“…Sialorrhoea is a socially disabling problem in bulbar amyotrophic lateral sclerosis (ALS). Botulinum toxin A (BoNT/A) was injected into the salivary glands in…”
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Altered innate immune response of plasmacytoid dendritic cells in multiple sclerosis by Bayas, A, Stasiolek, M, Kruse, N, Toyka, K.V, Selmaj, K, Gold, R

“…Plasmacytoid dendritic cells (pDCs) are of crucial importance in immune regulation and response to microbial factors. In multiple sclerosis (MS), pDCs from…”
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Preserved myelin integrity and reduced axonopathy in connexin32‐deficient mice lacking the recombination activating gene‐1 by Kobsar, I., Berghoff, M., Samsam, M., Wessig, C., Mäurer, M., Toyka, K. V., Martini, R.

“…Mice heterozygously deficient for myelin protein zero (P0) mimicking human Charcot–Marie–Tooth (CMT) disease 1B show T‐lymphocyte and macrophage upregulation…”
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Serum antibodies to conformational and linear epitopes of myelin oligodendrocyte glycoprotein are not elevated in the preclinical phase of multiple sclerosis by Chan, A., Decard, BF, Franke, C., Grummel, V., Zhou, D., Schottstedt, V., Toyka, KV, Hemmer, B., Gold, R.

“…Background: The proposed predictive value of serum anti-myelin antibodies for the development of multiple sclerosis after a first clinically isolated syndrome…”
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Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques by Gold, R, Schmied, M, Giegerich, G, Breitschopf, H, Hartung, H P, Toyka, K V, Lassmann, H

“…A number of enzymatic techniques have recently been developed to detect DNA fragmentation in apoptosis at the cellular level. However, since DNA fragmentation…”
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Neuropathology and binding studies in anti-amphiphysin-associated stiff-person syndrome by WESSIG, C, KLEIN, R, SCHNEIDER, M. F, TOYKA, K. V, NAUMANN, M, SOMMER, C

“…The authors report a 71-year-old woman with amphiphysin-associated paraneoplastic stiff-person syndrome, opsoclonus, and encephalopathy. The patient's symptoms…”
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Diagnostic value of sural nerve matrix metalloproteinase-9 in diabetic patients with CIDP by JANN, S, BRAMERIO, M. A, BERETTA, S, KOCH, S, DEFANTI, C. A, TOYKA, K. V, SOMMER, C

“…Patients with diabetes mellitus (DM) may develop chronic inflammatory demyelinating polyneuropathy (CIDP), which may be difficult to distinguish from diabetic…”
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Absence of reuptake of serotonin influences susceptibility to clinical autoimmune disease and neuroantigen‐specific interferon‐gamma production in mouse EAE by Hofstetter, H. H., Mössner, R., Lesch, K. P., Linker, R. A., Toyka, K. V., Gold, R.

“…Summary Serotonin (5‐hydroxytryptamine, 5‐HT) is one of the most extensively studied neurotransmitters of the central nervous system. It also has been…”
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