Search Results - "Townsend, Dana"
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HIV-1 Integrase Binds the Viral RNA Genome and Is Essential during Virion Morphogenesis
Published in Cell (25-08-2016)“…While an essential role of HIV-1 integrase (IN) for integration of viral cDNA into human chromosome is established, studies with IN mutants and allosteric IN…”
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Nucleotide resolution mapping of influenza A virus nucleoprotein-RNA interactions reveals RNA features required for replication
Published in Nature communications (31-01-2018)“…Influenza A virus nucleoprotein (NP) association with viral RNA (vRNA) is essential for packaging, but the pattern of NP binding to vRNA is unclear. Here we…”
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Reduced insulin sensitivity in young, normoglycaemic subjects alters microvascular tissue oxygenation during postocclusive reactive hyperaemia
Published in Experimental physiology (01-06-2019)“…New Findings What is the central question of the study? Are measures of reduced insulin sensitivity in young, normoglycaemic subjects correlated with…”
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Integrase-RNA interactions underscore the critical role of integrase in HIV-1 virion morphogenesis
Published in eLife (22-09-2020)“…A large number of human immunodeficiency virus 1 (HIV-1) integrase (IN) alterations, referred to as class II substitutions, exhibit pleiotropic effects during…”
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Genome-Wide Analysis of Heterogeneous Nuclear Ribonucleoprotein (hnRNP) Binding to HIV-1 RNA Reveals a Key Role for hnRNP H1 in Alternative Viral mRNA Splicing
Published in Journal of virology (01-11-2019)“…Alternative splicing of HIV-1 mRNAs increases viral coding potential and controls the levels and timing of gene expression. HIV-1 splicing is regulated in part…”
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Effect of assuming constant tissue scattering on measured tissue oxygenation values during tissue ischemia and vascular reperfusion
Published in Journal of applied physiology (1985) (01-07-2019)“…The purpose of this study was to determine the effects of assuming constant tissue scattering properties on tissue oxygenation measurements during a vascular…”
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Muscle capillary blood flow kinetics estimated from pulmonary O2 uptake and near-infrared spectroscopy
Published in Journal of applied physiology (1985) (01-05-2005)“…Departments of Anatomy and Physiology and Kinesiology, Kansas State University, Manhattan, Kansas Submitted 20 August 2004 ; accepted in final form 4 January…”
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Characterizing near-infrared spectroscopy responses to forearm post-occlusive reactive hyperemia in healthy subjects
Published in European journal of applied physiology (01-11-2011)“…During post-occlusive reactive hyperemia (PORH) there is a temporary increase in the total hemoglobin + myoglobin (T[Hb+Mb]) signal as measured by…”
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Relationship between brachial artery blood flow and total [hemoglobin+myoglobin] during post-occlusive reactive hyperemia
Published in Microvascular research (01-01-2014)“…The associations between macrovascular and microvascular responses reported previously during post-occlusive reactive hyperemia have been inconsistent. The…”
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Effects of a high-fat meal on pulmonary function in healthy subjects
Published in European journal of applied physiology (01-06-2010)“…Obesity has important health consequences, including elevating risk for heart disease, diabetes, and cancer. A high-fat diet is known to contribute to obesity…”
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Insulin resistance and metabolic syndrome criteria in lean, normoglycemic college-age subjects
Published in Diabetes & metabolic syndrome clinical research & reviews (01-09-2018)“…The goal of this study was to determine insulin sensitivity in a fasted state and during an oral glucose tolerance test (OGTT), in normoglycemic (NGT), lean…”
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Effects of inspiratory muscle training on exercise responses in normoxia and hypoxia
Published in Respiratory physiology & neurobiology (14-05-2007)“…Abstract The purpose of this study was to determine the effects of inspiratory muscle training (IMT) on exercise in hypoxia (H) and normoxia (N). A 4-week IMT…”
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Human femoral artery and estimated muscle capillary blood flow kinetics following the onset of exercise
Published in Experimental physiology (01-07-2006)“…The purpose of this study was to compare the kinetics of estimated capillary blood flow to those of femoral artery blood flow and estimated muscle oxygen…”
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Muscle contraction-blood flow interactions during upright knee extension exercise in humans
Published in Journal of applied physiology (1985) (01-04-2005)“…1 Department of Kinesiology, Kansas State University, Manhattan, Kansas; 2 Department of Exercise Science and Physiology, Hiroshima Prefectural Women's…”
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Effects of pedal frequency on estimated muscle microvascular O2 extraction
Published in European journal of applied physiology (01-03-2006)“…An increase in muscle contraction frequency could limit muscle blood flow QM compromising the matching of QM and muscle oxygen uptake VO2M. This study examined…”
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Kinetics of estimated human muscle capillary blood flow during recovery from exercise
Published in Experimental physiology (01-09-2005)“…The kinetic characteristics of muscle capillary blood flow during recovery from exercise are controversial (e.g. one versus two phases). Furthermore, it is not…”
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Matching of blood flow to metabolic rate during recovery from moderate exercise in humans
Published in Experimental physiology (01-10-2008)“…It is unclear whether measurement of limb or conduit artery blood flow during recovery from exercise provides an accurate representation of flow to the muscle…”
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Dynamics of skeletal muscle oxygenation during sequential bouts of moderate exercise
Published in Experimental physiology (01-05-2005)“…In rat muscle, faster dynamics of microvascular P O 2 (approximately blood flow to O 2 uptake ratio) after prior contractions that did not alter blood…”
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Effects of Sleep Duration on Insulin Resistance – A Longitudinal Study in Healthy, Lean, College‐Age, Males
Published in The FASEB journal (01-04-2017)“…Abstract only Introduction There are sparse interventional, within subject, clinical sleep studies. College‐age adults can experience substantial changes in…”
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