Search Results - "Towbin, Kenneth"

Editorial: Not the Same as Adults: Vortioxetine in Adolescents With Major Depression by Towbin, Kenneth E.

“…In this issue, readers can review a multisite, double-blind, randomized, controlled trial (DBRCT) of vortioxetine for adolescent major depression (AMD) by…”
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Association of Irritability and Anxiety With the Neural Mechanisms of Implicit Face Emotion Processing in Youths With Psychopathology by Stoddard, Joel, Tseng, Wan-Ling, Kim, Pilyoung, Chen, Gang, Yi, Jennifer, Donahue, Laura, Brotman, Melissa A, Towbin, Kenneth E, Pine, Daniel S, Leibenluft, Ellen

“…Psychiatric comorbidity complicates clinical care and confounds efforts to elucidate the pathophysiology of commonly occurring symptoms in youths. To our…”
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Brain Mechanisms of Attention Orienting Following Frustration: Associations With Irritability and Age in Youths by Tseng, Wan-Ling, Deveney, Christen M, Stoddard, Joel, Kircanski, Katharina, Frackman, Anna E, Yi, Jennifer Y, Hsu, Derek, Moroney, Elizabeth, Machlin, Laura, Donahue, Laura, Roule, Alexandra, Perhamus, Gretchen, Reynolds, Richard C, Roberson-Nay, Roxann, Hettema, John M, Towbin, Kenneth E, Stringaris, Argyris, Pine, Daniel S, Brotman, Melissa A, Leibenluft, Ellen

“…Objective:Childhood irritability is a common, impairing problem with changing age-related manifestations that predict long-term adverse outcomes. However, more…”
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The NIMH Child Emotional Faces Picture Set (NIMH-ChEFS): a new set of children's facial emotion stimuli by Egger, Helen Link, Pine, Daniel S., Nelson, Eric, Leibenluft, Ellen, Ernst, Monique, Towbin, Kenneth E., Angold, Adrian

“…With the emergence of new technologies, there has been an explosion of basic and clinical research on the affective and cognitive neuroscience of face…”
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White matter microstructure in youth with and at risk for bipolar disorder by Linke, Julia O., Stavish, Caitlin, Adleman, Nancy E., Sarlls, Joelle, Towbin, Kenneth E., Leibenluft, Ellen, Brotman, Melissa A.

“…Objectives Bipolar disorder (BD) and familial risk for BD have been associated with aberrant white matter (WM) microstructure in the corpus callosum and…”
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Empirically derived patterns of psychiatric symptoms in youth: A latent profile analysis by Kircanski, Katharina, Zhang, Susan, Stringaris, Argyris, Wiggins, Jillian Lee, Towbin, Kenneth E, Pine, Daniel S, Leibenluft, Ellen, Brotman, Melissa A

“…Abstract Background By conceptualizing domains of behavior transdiagnostically, the National Institute of Mental Health Research Domain Criteria (NIMH RDoC)…”
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Complementary Features of Attention Bias Modification Therapy and Cognitive-Behavioral Therapy in Pediatric Anxiety Disorders by White, Lauren K, Sequeira, Stefanie, Britton, Jennifer C, Brotman, Melissa A, Gold, Andrea L, Berman, Erin, Towbin, Kenneth, Abend, Rany, Fox, Nathan A, Bar-Haim, Yair, Leibenluft, Ellen, Pine, Daniel S

“…Objective:In the treatment of anxiety disorders, attention bias modification therapy (ABMT) and cognitive-behavioral therapy (CBT) may have complementary…”
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A Randomized Controlled Trial of Computerized Interpretation Bias Training for Disruptive Mood Dysregulation Disorder: A Fast-Fail Study by Haller, Simone P., Stoddard, Joel, Botz-Zapp, Christian, Clayton, Michal, MacGillivray, Caroline, Perhamus, Gretchen, Stiles, Kelsey, Kircanski, Katharina, Penton-Voak, Ian S., Bar-Haim, Yair, Munafò, Marcus, Towbin, Kenneth E., Brotman, Melissa A.

“…To examine targeted, mechanism-based interventions is the next generation of treatment innovation. Biased threat labeling of ambiguous face emotions…”
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Reduced Amygdala Response to Fearful Expressions in Children and Adolescents With Callous-Unemotional Traits and Disruptive Behavior Disorders by Marsh, Abigail A., Finger, Elizabeth C., Mitchell, Derek G.V., Reid, Marguerite E., Sims, Courtney, Kosson, David S., Towbin, Kenneth E., Leibenluft, Ellen, Pine, Daniel S., Blair, R. J.R.

“…Objective: Extensive work implicates abnormal amygdala activation in emotional facial expression processing in adults with callous-unemotional traits. However,…”
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Mood and Behaviors of Adolescents With Depression in a Longitudinal Study Before and During the COVID-19 Pandemic by Sadeghi, Neda, Fors, Payton Q., Eisner, Lillian, Taigman, Jeremy, Qi, Karen, Gorham, Lisa S., Camp, Christopher C., O’Callaghan, Georgia, Rodriguez, Diana, McGuire, Jerry, Garth, Erin M., Engel, Chana, Davis, Mollie, Towbin, Kenneth E., Stringaris, Argyris, Nielson, Dylan M.

“…To investigate whether, compared to pre-pandemic levels, depressive and anxiety symptoms in adolescents with depression increased during the pandemic. We used…”
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Autism Spectrum Disorder Scale Scores in Pediatric Mood and Anxiety Disorders by PINE, DANIEL S., M.D, GUYER, AMANDA E., Ph.D, GOLDWIN, MICHELLE, B.A, TOWBIN, KENNETH A., M.D, LEIBENLUFT, ELLEN, M.D

“…ABSTRACT Objective: To compare scores on autism spectrum disorder (ASD) symptom scales in healthy youths and youths with mood or anxiety disorders. Method: A…”
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Behavioral and Neural Sustained Attention Deficits in Disruptive Mood Dysregulation Disorder and Attention-Deficit/Hyperactivity Disorder by Pagliaccio, David, PhD, Wiggins, Jillian Lee, PhD, Adleman, Nancy E., PhD, Curhan, Alexa, BA, Zhang, Susan, BA, Towbin, Kenneth E., MD, Brotman, Melissa A., PhD, Pine, Daniel S., MD, Leibenluft, Ellen, MD

“…Abstract Objective Disruptive mood dysregulation disorder (DMDD), characterized by severe irritability, and attention-deficit/hyperactivity disorder (ADHD) are…”
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Parsing neurodevelopmental features of irritability and anxiety: Replication and validation of a latent variable approach by Cardinale, Elise M, Kircanski, Katharina, Brooks, Julia, Gold, Andrea L, Towbin, Kenneth E, Pine, Daniel S, Leibenluft, Ellen, Brotman, Melissa A

“…Irritability and anxiety are two common clinical phenotypes that involve high-arousal negative affect states (anger and fear), and that frequently co-occur…”
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White Matter Microstructure in Pediatric Bipolar Disorder and Disruptive Mood Dysregulation Disorder by Linke, Julia O., Adleman, Nancy E., Sarlls, Joelle, Ross, Andrew, Perlstein, Samantha, Frank, Heather R., Towbin, Kenneth E., Pine, Daniel S., Leibenluft, Ellen, Brotman, Melissa A.

“…Disruptive mood dysregulation disorder (DMDD) codifies severe, chronic irritability. Youths with bipolar disorder (BD) also present with irritability, but with…”
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The Clinician Affective Reactivity Index: Validity and Reliability of a Clinician-Rated Assessment of Irritability by Haller, Simone P., Kircanski, Katharina, Stringaris, Argyris, Clayton, Michal, Bui, Hong, Agorsor, Courtney, Cardenas, Sofia I., Towbin, Kenneth E., Pine, Daniel S., Leibenluft, Ellen, Brotman, Melissa A.

“…•The CL-ARI is a clinician-rated instrument that dimensionally assesses pediatric irritability.•The instrument can be used to assess transdiagnostic…”
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Differentiating Bipolar Disorder–Not Otherwise Specified and Severe Mood Dysregulation by Towbin, Kenneth, M.D, Axelson, David, M.D, Leibenluft, Ellen, M.D, Birmaher, Boris, M.D

“…Objective Bipolar disorder–not otherwise specified (BP-NOS) and severe mood dysregulation (SMD) are severe mood disorders that were defined to address…”
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Test-retest reliability and validity of a frustration paradigm and irritability measures by Tseng, Wan-Ling, Moroney, Elizabeth, Machlin, Laura, Roberson-Nay, Roxann, Hettema, John M, Carney, Dever, Stoddard, Joel, Towbin, Kenneth A, Pine, Daniel S, Leibenluft, Ellen, Brotman, Melissa A

“…Abstract Background Data on the reliability and validity of assessments for irritability, particularly behavioral paradigms, are limited. This study examined…”
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A preliminary study on functional activation and connectivity during frustration in youths with bipolar disorder by Ross, Andrew J., Roule, Alexandra L., Deveney, Christen M., Towbin, Kenneth E., Brotman, Melissa A., Leibenluft, Ellen, Tseng, Wan‐Ling

“…Objectives Frustration is associated with impaired attention, heightened arousal, and greater unhappiness in youths with bipolar disorder (BD) vs healthy…”
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Behavioral and Neural Sustained Attention Deficits in Bipolar Disorder and Familial Risk of Bipolar Disorder by Pagliaccio, David, Wiggins, Jillian Lee, Adleman, Nancy E, Harkins, Elizabeth, Curhan, Alexa, Towbin, Kenneth E, Brotman, Melissa A, Pine, Daniel S, Leibenluft, Ellen

“…Abstract Background Few neuroimaging studies compare individuals affected with bipolar disorder (BP), at high familial risk of BP, and at low risk to identify…”
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The Inventory of Callous-Unemotional Traits (ICU) in Children: Reliability and Heritability by Moore, Ashlee A., Carney, Dever, Moroney, Elizabeth, Machlin, Laura, Towbin, Kenneth E., Brotman, Melissa A., Pine, Daniel S., Leibenluft, Ellen, Roberson-Nay, Roxann, Hettema, John M.

“…Callous-unemotional (CU) traits comprise the core symptoms of psychopathy, yet no study has estimated the heritability of CU traits in a community sample of…”
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