Search Results - "Tovey, Michaël G"

Concomitant type I IFN receptor-triggering of T cells and of DC is required to promote maximal modified vaccinia virus Ankara-induced T-cell expansion by Frenz, Theresa, Waibler, Zoe, Hofmann, Janin, Hamdorf, Matthias, Lantermann, Markus, Reizis, Boris, Tovey, Michaël G, Aichele, Peter, Sutter, Gerd, Kalinke, Ulrich

“…Virus-induced expansion of CD8⁺ T cells may be promoted by type I IFN receptor (IFNAR)-triggering of T cells, depending on the pathogen tested. We studied…”
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Involvement of the Gab2 scaffolding adapter in type I interferon signalling by Baychelier, Florence, Nardeux, Pierre-Claude, Cajean-Feroldi, Chantal, Ermonval, Myriam, Guymarho, Jacqueline, Tovey, Michaël G., Eid, Pierre

“…Interferons (IFNs) are pleiotropic cytokines involved in the regulation of physiological and pathological processes. Upon interaction with their specific…”
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Quantification of Bevacizumab Activity Following Treatment of Patients With Ovarian Cancer or Glioblastoma by Lallemand, Christophe, Ferrando-Miguel, Rosa, Auer, Michael, Iglseder, Sarah, Czech, Theresa, Gaber-Wagener, Anouk, Di Pauli, Franziska, Deisenhammer, Florian, Tovey, Michael G

“…Highly sensitive reporter-gene assays have been developed that allow both the direct vascular endothelial growth factor (VEGF) neutralizing activity of…”
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Adjuvant activity of type I interferons by Tovey, Michael G, Lallemand, Christophe, Thyphronitis, George

“…Type I interferons (IFNs) produced primarily by plasmacytoid dendritic cells (pDCs) as part of the innate immune response to infectious agents induce the…”
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Presensitizing with a Toll-like receptor 3 ligand impairs CD8 T-cell effector differentiation and IL-33 responsiveness by Ngoi, Soo Mun, St. Rose, Marie-Clare, Menoret, Antoine M, Smith, Dirk E, Tovey, Michael G, Adler, Adam J, Vella, Anthony T

“…The synthetic double-stranded RNA poly(I:C) is commonly used as an adjuvant to boost CD8 T-cell function; however, polyinosinic:polycytidylic acid [poly(I:C)]…”
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A Novel System for the Quantification of the ADCC Activity of Therapeutic Antibodies by Tovey, Michael G., Huang, Lue, Vallette, Benoit, Simansour, Maud, Staub, Flore, Liang, Feifei, Lallemand, Christophe, Ferrando-Miguel, Rosa

“…Novel ADCC effector cells expressing the V-variant or F-variant of FcγRIIIa (CD16a) and firefly luciferase under the control of a chimeric promoter…”
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Cryptosporidium parvum Infection Rapidly Induces a Protective Innate Immune Response Involving Type I Interferon by Barakat, Farah M., McDonald, Vincent, Foster, Graham R., Tovey, Michael G., Korbel, Daniel S.

“…Type II interferon (IFN), IFN-γ, is important in innate immunity to the intestinal protozoan parasite Cryptosporidium species, which infects epithelial cells…”
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Safety, Tolerability, and Immunogenicity of Interferons by Tovey, Michael G, Lallemand, Christophe

“…Interferons (IFNs) are class II cytokines that are key components of the innate immune response to virus infection. Three IFN sub-families, type I, II, and III…”
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Type I Interferons Mediate the Innate Cytokine Response to Recombinant Fowlpox Virus but Not the Induction of Plasmacytoid Dendritic Cell-Dependent Adaptive Immunity by Lousberg, Erin L, Fraser, Cara K, Tovey, Michael G, Diener, Kerrilyn R, Hayball, John D

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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TL1A: A Mediator of Gut Inflammation by Young, Howard A., Tovey, Michael G.

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Adjuvant activity of interferon alpha: mechanism(s) of action by Tovey, Michael G., Lallemand, Christophe, Meritet, Jean-Francois, Maury, Chantal

“…Interferon alpha (IFNα), produced primarily by plasmacytoid dendritic cells as part of the innate immune response to infectious agents, is a powerful…”
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Upon intranasal vesicular stomatitis virus infection, astrocytes in the olfactory bulb are important interferon Beta producers that protect from lethal encephalitis by Detje, Claudia N, Lienenklaus, Stefan, Chhatbar, Chintan, Spanier, Julia, Prajeeth, Chittappen K, Soldner, Claudia, Tovey, Michael G, Schlüter, Dirk, Weiss, Siegfried, Stangel, Martin, Kalinke, Ulrich

“…Previously we found that following intranasal (i.n.) infection with neurotropic vesicular stomatitis virus (VSV) type I interferon receptor (IFNAR) triggering…”
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Immunogenicity and other problems associated with the use of biopharmaceuticals by Tovey, Michael G., Lallemand, Christophe

“…Biopharmaceuticals are used widely for the treatment of cancer, chronic viral hepatitis, inflammatory, and autoimmune diseases. Biopharmaceuticals such as…”
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Mycobacterial Antigens Exacerbate Disease Manifestations in Mycobacterium tuberculosis-Infected Mice by MOREIRA, Andre L, TSENOVA, Liana, FREEDMAN, Victoria H, KAPLAN, Gilla, HAILE AMAN, Melles, BEKKER, Linda-Gail, FREEMAN, Sherry, MANGALISO, Bande, SCHRÖDER, Ulf, JAGIRDAR, Jaishree, ROM, William N, TOVEY, Michael G

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Reporter gene assay for the quantification of the activity and neutralizing antibody response to TNFα antagonists by Lallemand, Christophe, Kavrochorianou, Nadia, Steenholdt, Casper, Bendtzen, Klaus, Ainsworth, Mark A., Meritet, Jean-Francois, Blanchard, Brigitte, Lebon, Pierre, Taylor, Peter, Charles, Peter, Alzabin, Saba, Tovey, Michael G.

“…A cell-based assay has been developed for the quantification of the activity of TNFα antagonists based on human erythroleukemic K562 cells transfected with a…”
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Targeting poly(I:C) to the TLR3-independent pathway boosts effector CD8 T cell differentiation through IFN-alpha/beta by Ngoi, Soo M, Tovey, Michael G, Vella, Anthony T

“…Poly(I:C) is an adjuvant used for antitumor treatment and vaccines because of its prominent effects on CD8 T cells and NK cells. Poly(I:C) binds TLR3 and this…”
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Locally Administered TLR7 Agonists Drive Systemic Antitumor Immune Responses That Are Enhanced by Anti-CD40 Immunotherapy by Broomfield, Steve A, van der Most, Robbert G, Prosser, Amy C, Mahendran, Sathish, Tovey, Michael G, Smyth, Mark J, Robinson, Bruce W. S, Currie, Andrew J

“…Topical application of tumors with the TLR7 agonist imiquimod is an effective adjunct treatment for a range of primary dermatological cancers. However, for…”
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Scrg1, a novel protein of the CNS is targeted to the large dense-core vesicles in neuronal cells by Dandoy-Dron, Françoise, Griffond, Bernadette, Mishal, Zohar, Tovey, Michael G., Dron, Michel

“…Scrapie responsive gene one (Scrg1) is a novel transcript discovered through identification of the genes associated with or responsible for the…”
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Adjuvant activity of cytokines by Tovey, Michael G, Lallemand, Christophe

“…The activity of several potent adjuvants, including incomplete Freund's adjuvant, CpG oligodeoxynucleotides, and alum, has been shown to be due at least in…”
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Immunotherapy of multiple sclerosis by Tovey, Michael G

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