Search Results - "Tourkova, I L"

Comparative analysis of CD1a, S-100, CD83, and CD11c human dendritic cells in normal, premalignant, and malignant tissues by Perez, L, Shurin, M R, Collins, B, Kogan, D, Tourkova, I L, Shurin, G V

“…A number of antibodies that recognize human dendritic cells (DC) have been identified. The main aim of this study was to compare and contrast different antigen…”
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Mechanisms of dendritic cell-induced T cell proliferation in the primary MLR assay by Tourkova, Irina L., Yurkovetsky, Zoya R., Shurin, Michael R., Shurin, Galina V.

“…DC are unique antigen presenting cells, and their ability to induce proliferation of T cells in a mixed leukocyte reaction (MLR) assay is commonly used for the…”
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Human renal cell carcinoma inhibits dendritic cell maturation and functions by Song, E Y, Shurin, M R, Tourkova, I L, Chatta, G, Shurin, G V

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Loss of New Chemokine CXCL14 in Tumor Tissue Is Associated with Low Infiltration by Dendritic Cells (DC), while Restoration of Human CXCL14 Expression in Tumor Cells Causes Attraction of DC Both In Vitro and In Vivo by Shurin, Galina V, Ferris, Robert, Tourkova, Irina L, Perez, Lori, Lokshin, Anna, Balkir, Levent, Collins, Bobby, Chatta, Gurkamal S, Shurin, Michael R

“…Breast and kidney-expressed chemokine (BRAK) CXCL14 is a new CXC chemokine with unknown function and receptor selectivity. The majority of head and neck…”
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Loss of new chemokine CXCL14 in tumor tissue is associated with low infiltration by dendritic cells (DC), while restoration of human CXCL14 expression in tumor cells causes attraction of DC both in vitro and in vivo by Shurin, G. V., Ferris, R., Tourkova, I. L., Perez, L., Lokshin, A., Balkir, L., Collins, B., Chatta, G. S., Shurin, M. R.

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Restoration by IL-15 of MHC Class I Antigen-Processing Machinery in Human Dendritic Cells Inhibited by Tumor-Derived Gangliosides by Tourkova, Irina L, Shurin, Galina V, Chatta, Gurkamal S, Perez, Lori, Finke, James, Whiteside, Theresa L, Ferrone, Soldano, Shurin, Michael R

“…We have recently reported that MHC class I Ag-processing machinery (APM) component expression in dendritic cells (DC) might be down-regulated by tumor cells…”
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Low-dose Chemotherapeutic Agents Regulate Small Rho GTPase Activity in Dendritic Cells by SHURIN, Galina V, TOURKOVA, Irina L, SHURIN, Michael R

“…Conventional chemotherapy targets dividing tumor cells and might support antitumor immunity by providing tumor antigens from dying tumor cells to…”
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Small Rho GTPases Regulate Antigen Presentation in Dendritic Cells by Shurin, Galina V, Tourkova, Irina L, Chatta, Gurkamal S, Schmidt, Gudula, Wei, Sheng, Djeu, Julie Y, Shurin, Michael R

“…Dendritic cells (DC) are involved in the regulation of innate and adaptive immunity. However, the molecular mechanisms maintaining DC function remain to be…”
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Inhibition of CD40 expression and CD40‐mediated dendritic cell function by tumor‐derived IL‐10 by Shurin, Michael R., Yurkovetsky, Zoya R., Tourkova, Irina L., Balkir, Levent, Shurin, Galina V.

“…As CD40 plays a key role in both antitumor immunity and DC maturation, we have studied the regulation of its expression during DC hematopoiesis (dendropoiesis)…”
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Inhibition of dendropoiesis by tumor derived and purified prostate specific antigen by Aalamian, Maryam, Tourkova, Irina L, Chatta, Gurkamal S, Lilja, Hans, Huland, Edith, Huland, Hartwig, Shurin, Galina V, Shurin, Michael R

“…Prostate specific antigen (PSA) is a serine protease produced by the prostate gland at high concentrations. Serum PSA may be significantly elevated in prostate…”
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Lung cancer-derived bombesin-like peptides down-regulate the generation and function of human dendritic cells by Makarenkova, Valeria P., Shurin, Galina V., Tourkova, Irina L., Balkir, Levent, Pirtskhalaishvili, Georgi, Perez, Lori, Gerein, Valentin, Siegfried, Jill M., Shurin, Michael R.

“…Development of tumors is regulated by tumor-derived neuroendocrine factors, including bombesin-like peptides (BLP). We have evaluated neuroendocrine regulation…”
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Increased function and survival of IL-15-transduced human dendritic cells are mediated by up-regulation of IL-15Rα and Bcl-2 by Tourkova, Irina L., Yurkovetsky, Zoya R., Gambotto, Andrea, Makarenkova, Valeria P., Perez, Lori, Balkir, Levent, Robbins, Paul D., Shurin, Michael R., Shurin, Galina V.

“…It has been recently demonstrated that dendritic cells (DC) coincubated with interleukin (IL)‐15 express high levels of the Bcl‐2 family of proteins and…”
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Murine prostate cancer inhibits both in vivo and in vitro generation of dendritic cells from bone marrow precursors by Tourkova, Irina L., Yamabe, Kazuo, Foster, Barbara, Chatta, Gurkamal, Perez, Lori, Shurin, Galina V., Shurin, Michael R.

“…BACKGROUND There is increasing evidence to suggest that dendritic cells (DC) are functionally impaired in tumor bearing hosts. However there is little or no…”
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Regulation of dendritic cell expansion in aged athymic nude mice by FLT3 ligand by Shurin, Galina V, Chatta, Gurkamal S, Tourkova, Irina L, Zorina, Tatiana D, Esche, Clemens, Shurin, Michael R

“…This report describes age-related alterations of dendritic cells (DC) distribution in nude athymic mice in vivo and reversal of certain age-dependent defects…”
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NK cells mediate Flt3 ligand-induced protection of dendritic cell precursors in vivo from the inhibition by prostate carcinoma in the murine bone marrow metastasis model by TOURKOVA, Irina L, YAMABE, Fazuo, CHATTA, Gurkamal, SHURIN, Galina V, SHURIN, Michael R

“…Multiple observations suggest that suppression of the dendritic cell (DC) system might be one of the mechanisms used by the tumors to escape immune response…”
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Comparative analysis of dendritic cells transduced with different anti-apoptotic molecules: sensitivity to tumor-induced apoptosis by Balkir, Levent, Tourkova, Irina L., Makarenkova, Valeria P., Shurin, Galina V., Robbins, Paul D., Yin, Xiao-Ming, Chatta, Gurkamal, Shurin, Michael R.

“…Background Tumors develop mechanisms to escape recognition by the immune system. It has recently been demonstrated that tumors cause apoptotic death of key…”
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