Retention and Predictors of Attrition Among People Living With HIV on Antiretroviral Therapy in Guinea: A 13-Year Historical Cohort Study in Nine Large-Volume Sites

The objective of this study was to estimate the retention rate of patients in an ART program and identify the predictors of attrition. This was a historical cohort study of HIV patients who started ART between September 2007 and April 2020, and were followed up on for at least 6 months in nine large...

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Bibliographic Details
Published in:	International journal of public health Vol. 68; p. 1605929
Main Authors:	Leno, Niouma Nestor, Guilavogui, Foromo, Camara, Alioune, Kadio, Kadio Jean-Jacques Olivier, Guilavogui, Timothé, Diallo, Thierno Saidou, Diallo, Mamadou Aliou, Leno, Daniel William Athanase, Ricarte, Button, Koita, Youssouf, Kaba, Laye, Ahiatsi, Arnold, Touré, Nagnouman, Traoré, Pascal, Chaloub, Souleymane, Kamano, André, Vicente, Carlos Arias, Delamou, Alexandre, Cissé, Mohamed
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 13-07-2023
Subjects:	antiretroviral therapy attrition HIV/AIDS predictors Public Health Archive retention HIV/AIDS predictors attrition antiretroviral therapy retention
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Summary:	The objective of this study was to estimate the retention rate of patients in an ART program and identify the predictors of attrition. This was a historical cohort study of HIV patients who started ART between September 2007 and April 2020, and were followed up on for at least 6 months in nine large-volume sites. Kaplan Meier techniques were used to estimate cumulative retention and attrition probabilities. Cox proportional hazards models were used to identify predictors of attrition. The cumulative probability of retention at 12 and 24 months was 76.2% and 70.2%, respectively. The attrition rate after a median follow-up time of 3.1 years was 35.2%, or an incidence of 11.4 per 100 person-years. Having initiated ART between 2012 and 2015; unmarried status; having initiated ART with CD4 count <100 cells/μL; and having initiated ART at an advanced clinical stage were factors significantly associated with attrition. The retention rate in our study is much lower than the proposed national target (90%). Studies to understand the reasons for loss to follow-up are needed.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Paola Daniore, University of Zurich, Switzerland Reviewed by: Aisha Yansaneh, United States Agency for International Development, United States Edited by: Jean Tenena Coulibaly, Félix Houphouët-Boigny University, Côte d'Ivoire
ISSN:	1661-8564 1661-8556 1661-8564
DOI:	10.3389/ijph.2023.1605929