Search Results - "Toukam, Marie"
-
1
A Lab‐On‐chip Tool for Rapid, Quantitative, and Stage‐selective Diagnosis of Malaria
Published in Advanced science (01-07-2021)“…Malaria remains the most important mosquito‐borne infectious disease worldwide, with 229 million new cases and 409.000 deaths in 2019. The infection is caused…”
Get full text
Journal Article -
2
Patient Preference for Subcutaneous Versus Intravenous Administration with Every-6-Week Natalizumab (Tysabri®) Dosing: NOVA Phase IIIb Extension Study (Part 2)
Published in Neurology and therapy (01-10-2024)“…Introduction Following NOVA (part 1) and the approval of the subcutaneous (SC) route of administration of natalizumab by the European Medicines Agency, an…”
Get full text
Journal Article -
3
608 Results of a phase 1 study investigating camidanlumab tesirine as monotherapy and in combination with pembrolizumab in patients with selected advanced solid tumors
Published in Journal for immunotherapy of cancer (01-11-2023)“…BackgroundCamidanlumab tesirine (Cami) is an anti-CD25 antibody conjugated to a pyrrolobenzodiazepine dimer cytotoxin designed to deplete CD25+ regulatory T…”
Get full text
Journal Article -
4
Diagnosis of Malaria: A Lab‐On‐chip Tool for Rapid, Quantitative, and Stage‐selective Diagnosis of Malaria (Adv. Sci. 14/2021)
Published in Advanced science (21-07-2021)“…In article 2004101, Marco Giacometti, Riccardo Bertacco and co‐workers reported on a diagnostic tool (TMek) based on paramagnetic properties of hemozoin…”
Get full text
Journal Article -
5
-
6
Exposure–response analysis of Camidanlumab tesirine in patients with relapsed or refractory classical Hodgkin lymphoma and non-Hodgkin lymphoma
Published in Cancer chemotherapy and pharmacology (2023)“…Purpose To investigate camidanlumab tesirine (Cami) exposure–response (E–R) relationships, using an integrated population pharmacokinetic model, for patients…”
Get full text
Journal Article -
7
Population pharmacokinetics analysis of camidanlumab tesirine in patients with relapsed or refractory Hodgkin lymphoma and non-Hodgkin lymphoma
Published in Cancer chemotherapy and pharmacology (2023)“…Purpose The objective of this analysis was to develop a population pharmacokinetic (PPK) model to characterize camidanlumab tesirine (Cami) pharmacokinetics…”
Get full text
Journal Article -
8
Characterization of OJT007 and OJT008 as Inhibitors of Methionine Aminopeptidases from Mycobacterium tuberculosis
Published in The FASEB journal (01-04-2019)“…Despite recent advances in the diagnosis of Tuberculosis (TB), the therapeutic management of this ancient disease is still challenging. Mycobacterium…”
Get full text
Journal Article -
9
Pre-clinical Studies of OJT008, a Novel Molecule Targeting Methionine Amino-Peptidase for the Treatment of Leishmaniasis
Published 01-01-2019“…Methionine aminopeptidase (MetAP) is a metalloprotease that catalyzes the cleavage of N-terminal methionine, the initiating amino acid for protein and…”
Get full text
Dissertation -
10
Pharmacokinetics and Pharmacodynamics of Natalizumab 6-Week Dosing vs Continued 4-Week Dosing for Relapsing-Remitting Multiple Sclerosis
Published in Neurology : neuroimmunology & neuroinflammation (01-12-2024)“…Exposure to natalizumab, an efficacious treatment for relapsing-remitting multiple sclerosis (RRMS), is associated with increased risk of progressive…”
Get full text
Journal Article -
11
Abstract 4151: Effect of camidanlumab tesirine (Cami) as monotherapy and in combination with pembrolizumab (PEM) on the immune cell profile in patients with selected advanced solid tumors
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract Background: Cami, an investigational anti-CD25, pyrrolobenzodiazepine-based antibody drug conjugate, imparts cytotoxicity on CD25+ regulatory T cells…”
Get full text
Journal Article -
12
Résultats de l’étude d’extension NOVA évaluant la préférence des patients pour l’administration sous-cutanée (SC) versus intraveineuse (IV) de natalizumab (NTZ) avec le schéma Q6W (toutes les 6 semaines)
Published in Revue neurologique (01-04-2024)“…La phase d’extension de NOVA (partie 2) évalue les administrations SC et IV de NTZ chez les patients traités Q6W en se concentrant sur leur préférence envers…”
Get full text
Journal Article