Search Results - "Toufektsian, M C"

Inhibition of cardiac leptin expression after infarction reduces subsequent dysfunction by Moro, C., Grauzam, S., Ormezzano, O., Toufektsian, M. C., Tanguy, S., Calabrese, P., Coll, J. L., Bak, I., Juhasz, B., Tosaki, A., de Leiris, J., Boucher, F.

“…Leptin is known to exert cardiodepressive effects and to induce left ventricular (LV) remodelling. Nevertheless, the autocrine and/or paracrine activities of…”
Get full text

Cardiac toxicity of singlet oxygen: implication in reperfusion injury by Toufektsian, M C, Boucher, F R, Tanguy, S, Morel, S, de Leiris, J G

“…Oxygen-derived free radicals (O2.-, H2O2, and .OH) that are produced during postischemic reperfusion are currently suspected to be involved in the pathogenesis…”
Get more information

Insulin resistance modifies plasma fatty acid distribution and decreases cardiac tolerance to in vivo ischaemia/reperfusion in rats by Morel, S, Berthonneche, C, Tanguy, S, Toufektsian, M-C, Foulon, T, De Lorgeril, M, De Leiris, J, Boucher, F

“…Summary 1. The early stage of insulin resistance, also termed the ‘prediabetic state’, is characterized by the development of hyperinsulinaemia, which…”
Get full text

Aging exacerbates hydrogen peroxide-induced alteration of vascular reactivity in rats by Tanguy, S, Boucher, F, Toufektsian, M C, Besse, S, de Leiris, J

“…Reactive oxygen species (ROS) such as superoxide anion (O2-*) and hydrogen peroxide (H2O2) can be produced by vascular endothelium and smooth muscle cells…”
Get more information

Effects of selenium deficiency on the response of cardiac tissue to ischemia and reperfusion by Toufektsian, Marie-Claire, Boucher, François, Pucheu, Sylvie, Tanguy, Stéphane, Ribuot, Christophe, Sanou, Drissa, Tresallet, Nicole, de Leiris, Joël

“…Over a 10-week period, female Wistar rats received a diet containing a low level of selenium, cofactor of the antioxidant enzyme glutathione peroxidase (GPx)…”
Get full text

Simultaneous evaluation of infarct size and cardiac function in intact mice by contrast-enhanced cardiac magnetic resonance imaging reveals contractile dysfunction in noninfarcted regions early after myocardial infarction by ZEQUAN YANG, BERR, Stuart S, GILSON, Wesley D, TOUFEKTSIAN, Marie-Claire, FRENCH, Brent A

“…The objective of this study was to noninvasively determine the effects of reperfused myocardial infarction (MI) on regional and global left-ventricular (LV)…”
Get full text

Role of reactive oxygen species in cardiac preconditioning: study with photoactivated Rose Bengal in isolated rat hearts by Toufektsian, M C, Tanguy, S, Jeunet, A, de Leiris, J G, Boucher, F R

“…Oxygen radical scavengers have been shown to prevent the development of ischemic preconditioning, suggesting that reactive oxygen species (ROS) might be…”
Get more information

Oral Selenium Supplementation in Rats does not Protect Isolated Rings of Aorta Against Exogenous Hydrogen Peroxide by Tanguy, S., Boucher, F., Besse, S., Toufektsian, M.C., Ducros, V., Favier, A., De Leiris, J.

Get full text

Effects of fasting and exogenous glucose delivery on cardiac tolerance to low-flow ischemia in adult and senescent rats by Boucher, François, Tanguy, Stéphane, Toufektsian, Marie-Claire, Besse, Sophie, de Leiris, Joël

“…Metabolic disorders due to changes in cytosolic glucose utilisation are suspected to be involved in the increased sensitivity of the aged myocardium to…”
Get full text

Assessment of non-reperfused and reperfused myocardial infarction using diffusible or deposited radiolabelled perfusion imaging agents by Riou, L M, Broisat, A, Lartizien, C, Toufektsian, M C, Maitrejean, S, Janier, M, Vanzetto, G, Fagret, D, Ghezzi, C

“…Incomplete microvascular reperfusion is often observed in patients undergoing thrombolytic therapy or angioplasty for acute myocardial infarction and has…”
Get full text

B005 Dietary-induced insulin resistance associated with dyslipidemia induces progressive cardiac dysfunction in rats as evidenced by echocardiography by Grauzam, S, Toufektsian, M.-C, Ormezzano, O, Jouan, M.-G, Boucher, F, Sulpice, T

“…Background A major complication of diabetes is the development of cardiac dysfunction in absence of vascular disease. Metabolic disorders such as insulin…”
Get full text

Activated platelets contribute importantly to myocardial reperfusion injury by Xu, Yaqin, Huo, Yuqing, Toufektsian, Marie-Claire, Ramos, Susan I, Ma, Yongguang, Tejani, Ankit D, French, Brent A, Yang, Zequan

“…Platelets become activated during myocardial infarction (MI), but the direct contribution of activated platelets to myocardial reperfusion injury in vivo has…”
Get more information

Preischemic selenium status as a major determinant of myocardial infarct size in vivo in rats by Tanguy, Stéphane, Morel, Sandrine, Berthonneche, Corinne, Toufektsian, Marie-Claire, de Lorgeril, Michel, Ducros, Véronique, Tosaki, Arpad, de Leiris, Joel, Boucher, François

“…Prospective epidemiological studies have shown that the incidence of numerous cardiovascular pathologies is correlated with body selenium status. However, it…”
Get more information

Dietary selenium intake affects cardiac susceptibility to ischaemia/reperfusion in male senescent rats by Tanguy, Stéphane, Toufektsian, Marie‐Claire, Besse, Sophie, Ducros, Véronique, de Leiris, Joël, Boucher, FranÇois

“…Background:  cardiovascular ageing is associated with an increase in cardiac susceptibility to ischaemia and reperfusion. This has been suggested to be partly…”
Get full text

Early pre-diabetic state alters adaptation of myocardial glucose metabolism during ischemia in rats by Morel, Sandrine, Berthonneche, Corinne, Tanguy, Stéphane, Toufektsian, Marie-Claire, Perret, Pascale, Ghezzi, Catherine, de Leiris, Joël, Boucher, François

“…Pre-diabetic subjects with high insulin secretory capacity have double risk of cardiovascular disease compared with subjects who do not develop…”
Get full text

Involvement of reactive oxygen species in cardiac preconditioning in rats by Toufektsian, Marie-Claire, Morel, Sandrine, Tanguy, Stéphane, Jeunet, André, de Leiris, Joël, Boucher, François

“…To date, the involvement of reactive oxygen species in ischemic preconditioning in vivo in rats is not clearly demonstrated. The aim of the present study was…”
Get more information

Selenium status as determinant of Connexin-43 dephosphorylation in ex vivo ischemic/reperfused rat myocardium by Rakotovao, Andry, Tanguy, Stéphane, Toufektsian, Marie-Claire, Berthonneche, Corinne, Ducros, Véronique, Tosaki, Arpad, Leiris, Joël de, Boucher, François

“…Recent studies have demonstrated that electrical uncoupling at gap junctions during ischemia is associated with cardiac Connexin-43 (Cx43) dephosphorylation…”
Get full text