Search Results - "Touboul, Jonathan"
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Is There Sufficient Evidence for Criticality in Cortical Systems?
Published in eNeuro (01-03-2021)“…Numerous studies have proposed that specific brain activity statistics provide evidence that the brain operates at a critical point, which could have…”
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Can power-law scaling and neuronal avalanches arise from stochastic dynamics?
Published in PloS one (11-02-2010)“…The presence of self-organized criticality in biology is often evidenced by a power-law scaling of event size distributions, which can be measured by linear…”
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In vitro characterization of the human segmentation clock
Published in Nature (London) (01-04-2020)“…The segmental organization of the vertebral column is established early in embryogenesis, when pairs of somites are rhythmically produced by the presomitic…”
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Progressive alignment of inhibitory and excitatory delay may drive a rapid developmental switch in cortical network dynamics
Published in Journal of neurophysiology (01-05-2020)“…Nervous system maturation occurs on multiple levels-synaptic, circuit, and network-at divergent timescales. For example, many synaptic properties mature…”
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Interplay of multiple pathways and activity-dependent rules in STDP
Published in PLoS computational biology (14-08-2018)“…Hebbian plasticity describes a basic mechanism for synaptic plasticity whereby synaptic weights evolve depending on the relative timing of paired activity of…”
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Neural mass activity, bifurcations, and epilepsy
Published in Neural computation (01-12-2011)“…In this letter, we propose a general framework for studying neural mass models defined by ordinary differential equations. By studying the bifurcations of the…”
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Noise-Induced Synchronization and Antiresonance in Interacting Excitable Systems: Applications to Deep Brain Stimulation in Parkinson’s Disease
Published in Physical review. X (01-03-2020)“…We study the nonlinear dynamics of a surprising phenomenon arising in large networks of excitable elements in response to noise: while at low noise, solutions…”
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Dynamics and bifurcations of the adaptive exponential integrate-and-fire model
Published in Biological cybernetics (01-11-2008)“…Recently, several two-dimensional spiking neuron models have been introduced, with the aim of reproducing the diversity of electrophysiological features…”
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Lhx2 regulates the timing of β-catenin-dependent cortical neurogenesis
Published in Proceedings of the National Academy of Sciences - PNAS (29-09-2015)“…The timing of cortical neurogenesis has a major effect on the size and organization of the mature cortex. The deletion of the LIM-homeodomain transcription…”
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Deep brain stimulation-guided optogenetic rescue of parkinsonian symptoms
Published in Nature communications (13-05-2020)“…Deep brain stimulation (DBS) of the subthalamic nucleus is a symptomatic treatment of Parkinson’s disease but benefits only to a minority of patients due to…”
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Large deviations for randomly connected neural networks: I. Spatially extended systems
Published in Advances in applied probability (01-09-2018)“…In a series of two papers, we investigate the large deviations and asymptotic behavior of stochastic models of brain neural networks with random interaction…”
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Symmetry breaking in the embryonic skin triggers directional and sequential plumage patterning
Published in PLoS biology (02-10-2019)“…The development of an organism involves the formation of patterns from initially homogeneous surfaces in a reproducible manner. Simulations of various…”
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Anti-Hebbian plasticity drives sequence learning in striatum
Published in Communications biology (09-05-2024)“…Spatio-temporal activity patterns have been observed in a variety of brain areas in spontaneous activity, prior to or during action, or in response to stimuli…”
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Engrams of Fast Learning
Published in Frontiers in cellular neuroscience (28-10-2020)“…Fast learning designates the behavioural and neuronal mechanisms underlying the acquisition of a long-term memory trace after a unique and brief experience. As…”
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Large Deviations, Dynamics and Phase Transitions in Large Stochastic and Disordered Neural Networks
Published in Journal of statistical physics (01-10-2013)“…Neuronal networks are characterized by highly heterogeneous connectivity, and this disorder was recently related experimentally to qualitative properties of…”
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Large deviations for randomly connected neural networks: II. State-dependent interactions
Published in Advances in applied probability (01-09-2018)“…We continue the analysis of large deviations for randomly connected neural networks used as models of the brain. The originality of the model relies on the…”
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A constructive mean-field analysis of multi-population neural networks with random synaptic weights and stochastic inputs
Published in Frontiers in computational neuroscience (18-02-2009)“…We deal with the problem of bridging the gap between two scales in neuronal modeling. At the first (microscopic) scale, neurons are considered individually and…”
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18
Synchronization in random balanced networks
Published in Physical review. E, Statistical, nonlinear, and soft matter physics (31-10-2013)“…Characterizing the influence of network properties on the global emerging behavior of interacting elements constitutes a central question in many areas, from…”
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Enhanced Abventricular Proliferation Compensates Cell Death in the Embryonic Cerebral Cortex
Published in Cerebral cortex (New York, N.Y. 1991) (01-10-2017)“…Loss of neurons in the neocortex is generally thought to result in a final reduction of cerebral volume. Yet, little is known on how the developing cerebral…”
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A "Numerical Evo-Devo" Synthesis for the Identification of Pattern-Forming Factors
Published in Cells (Basel, Switzerland) (05-08-2020)“…Animals display extensive diversity in motifs adorning their coat, yet these patterns have reproducible orientation and periodicity within species or groups…”
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