Search Results - "Totty, N"

Eotaxin : a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation by JOSE, P. J, GRIFFITHS-JOHNSON, D. A, COLLLINS, P. D, WALSH, D. T, MOQBEL, R, TOTTY, N. F, TRUONG, O, HSUAN, J. J, WILLIAMS, T. J

“…Eosinophil accumulation is a prominent feature of allergic inflammatory reactions, such as those occurring in the lung of the allergic asthmatic, but the…”
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Akt Phosphorylates the Yes-Associated Protein, YAP, to Induce Interaction with 14-3-3 and Attenuation of p73-Mediated Apoptosis by Basu, Subham, Totty, Nicholas F, Irwin, Meredith S, Sudol, Marius, Downward, Julian

“…We have used an affinity purification method to identify substrates of protein kinase B/Akt. One protein that associates with 14-3-3 in an Akt-dependent manner…”
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Redox-mediated substrate recognition by Sdp1 defines a new group of tyrosine phosphatases by McDonald, N. Q, Fox, G. C, Shafiq, M, Briggs, D. C, Knowles, P. P, Collister, M, Didmon, M. J, Makrantoni, V, Dickinson, R. J, Hanrahan, S, Totty, N, Stark, M. J. R, Keyse, S. M

“…Reactive oxygen species trigger cellular responses by activation of stress-responsive mitogen-activated protein kinase (MAPK) signalling pathways. Reversal of…”
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unr, a cellular cytoplasmic RNA-binding protein with five cold-shock domains, is required for internal initiation of translation of human rhinovirus RNA by Hunt, S L, Hsuan, J J, Totty, N, Jackson, R J

“…Initiation of translation of the animal picornavirus RNAs occurs via a mechanism of direct ribosome entry, which requires a segment of the 5' UTR of the RNA,…”
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Phospholipase D: A Downstream Effector of ARF in Granulocytes by Cockcroft, Shamshad, Geraint M. H. Thomas, Fensome, Amanda, Geny, Blandine, Cunningham, Emer, Gout, Ivan, Hiles, Ian, Totty, Nicholas F., Truong, Oanh, Hsuan, J. Justin

“…Activation of the phospholipase D (PLD) pathway is a widespread response when cells are activated by agonists that bind receptors on the cell surface. A 16-kD…”
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Modulation of the glycogen synthase kinase‐3 family by tyrosine phosphorylation by Hughes, K., Nikolakaki, E., Plyte, S.E., Totty, N.F., Woodgett, J.R.

“…Glycogen synthase kinase‐3 (GSK‐3) is a protein serine kinase implicated in the cellular response to insulin. The enzyme is the mammalian homologue of the…”
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A target for Src in mitosis by Fumagalli, Stefano, Totty, Nicholas F, Hsuan, J. Justin, Courtneidge, Sara A

“…The activity of the c-Src protein is increased during cell-cycle stage G1 in fibroblasts stimulated with certain growth factors, and at the G2/M transition,…”
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PI 3‐kinase is a dual specificity enzyme: autoregulation by an intrinsic protein‐serine kinase activity by Dhand, R., Hiles, I., Panayotou, G., Roche, S., Fry, M.J., Gout, I., Totty, N.F., Truong, O., Vicendo, P., Yonezawa, K.

“…Phosphatidylinositol 3‐kinase (PI 3‐kinase) has a regulatory 85 kDa adaptor subunit whose SH2 domains bind phosphotyrosine in specific recognition motifs, and…”
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Cloning of cDNAs encoding mammalian double-stranded RNA-specific adenosine deaminase by O'Connell, Mary A., Krause, Sabine, Higuchi, Miyoko, Hsuan, J. Justin, Totty, Nicholas F., Jenny, Andreas, Keller, Walter

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Macrophage migration inhibitory factor of the parasitic nematode Trichinella spiralis by Tan, T H, Edgerton, S A, Kumari, R, McAlister, M S, Roe, S M, Nagl, S, Pearl, L H, Selkirk, M E, Bianco, A E, Totty, N F, Engwerda, C, Gray, C A, Meyer, D J, Rowe, S M

“…cDNAs were obtained for macrophage migration-inhibitory factor (MIF)/L-dopachrome methyl ester tautomerase homologues from the parasitic nematodes Trichinella…”
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A new component of the transcription factor DRTF1/E2F by Girling, Rowena, Partridge, Janet F, Bandara, Lasantha R, Burden, Neil, Totty, Nicholas F, Hsuan, J. Justin, Thangue, Nicholas B. La

“…Transcription factor DRTF1/E2F coordinates events in the cell cycle with transcription by its cyclical interactions with important regulators of cellular…”
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Purification and Properties of Transgelin: A Transformation and Shape Change Sensitive Actin-Gelling Protein by Shapland, Claire, Hsuan, J. Justin, Totty, Nicholas F., Lawson, Durward

“…We have purified the transformation and shape change sensitive isoform of an actin associated polypeptide doublet previously described by us and have shown…”
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The Osteoclast Functional Antigen, Implicated in the Regulation of Bone Resorption, Is Biochemically Related to the Vitronectin Receptor by Davies, John, Warwick, Julia, Totty, Nicholas, Philp, Robin, Helfrich, Miep, Horton, Michael

“…We have defined the structure of the Osteoclast Functional Antigen (OFA) by immunological and biochemical means. OFA is an abundant surface antigen in human…”
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Apolipoprotein AI Mutation Arg-60 Causes Autosomal Dominant Amyloidosis by Soutar, Anne K., Hawkins, P. N., Vigushin, D. M., Tennent, Glenys A., Booth, Susanne E., Hutton, Therese, Nguyen, Oanh, Totty, N. F., Feest, T. G., Hsuan, J. J., Pepys, M. B.

“…A mutation in the gene for apolipoprotein AI (apoAI) was identified in an English family with autosomal dominant non-neuropathic systemic amyloidosis. The…”
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α-Latrotoxin Receptor, Latrophilin, Is a Novel Member of the Secretin Family of G Protein-coupled Receptors by Lelianova, Vera G., Davletov, Bazbek A., Sterling, Alistair, Rahman, M. Atiqur, Grishin, Eugene V., Totty, Nicholas F., Ushkaryov, Yuri A.

“…α-Latrotoxin (LTX) stimulates massive exocytosis of synaptic vesicles and may help to elucidate the mechanism of regulation of neurosecretion. We have recently…”
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Close similarity of epidermal growth factor receptor and v- erb-B oncogene protein sequences by Downward, J, Yarden, Y, Mayes, E, Scrace, G, Totty, N, Stockwell, P, Ullrich, A, Schlessinger, J, Waterfield, M. D

“…Each of six peptides derived from the human epidermal growth factor (EGF) receptor very closely matches a part of the deduced sequence of the v-erb-B…”
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Human lysozyme gene mutations cause hereditary systemic amyloidosis by Pepys, M. B, Hawkins, P. N, Booth, D. R, Vigushin, D. M, Tennent, G. A, Soutar, A. K, Totty, N, Nguyen, O, Blake, C. C. F, Terry, C. J, Feest, T. G, Zalin, A. M, Hsuan, J. J

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Alpha-enolase: A novel cytosolic autoantigen in ANCA positive vasculitis by Moodie, Fleur D.L., Leaker, Brian, Cambridge, Geraldine, Totty, Nicholas F., Segal, Anthony W.

“…Alpha-enolase: A novel cytosolic autoantigen in ANCA positive vasculitis. Anti-neutrophil cytoplasmic antibodies (ANCA) in sera from patients with clinically…”
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A family of AP-2 proteins regulates c-erbB-2 expression in mammary carcinoma by Bosher, J M, Totty, N F, Hsuan, J J, Williams, T, Hurst, H C

“…The proto-oncogene c-erbB-2 is overexpressed in 25-30% of breast cancers through increased transcription and amplification of the gene. We have previously…”
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SH2 Signaling in a Lower Eukaryote: A STAT Protein That Regulates Stalk Cell Differentiation in Dictyostelium by Kawata, Takefumi, Shevchenko, Andrej, Fukuzawa, Masashi, Jermyn, Keith A, Totty, Nicholas F, Zhukovskaya, Natasha V, Sterling, Alistair E, Mann, Matthias, Williams, Jeffrey G

“…The TTGA-binding factor is a transcriptional regulator activated by DIF, the chlorinated hexaphenone that induces prestalk cell differentiation in…”
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