Search Results - "Totsingan, Filbert"

Structure-Activity Relationship Assessment of Sophorolipid Ester Derivatives against Model Bacteria Strains by Totsingan, Filbert, Liu, Fei, Gross, Richard A

“…Sophorolipids (SLs) are glycolipids that consist of a hydrophilic sophorose head group covalently linked to a hydrophobic fatty acid tail. They are produced by…”
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Peptide nucleic acids with a structurally biased backbone. Updated review and emerging challenges by Corradini, Roberto, Sforza, Stefano, Tedeschi, Tullia, Totsingan, Filbert, Manicardi, Alex, Marchelli, Rosangela

“…Peptide nucleic acids (PNAs) are polyamidic oligonucleotide analogues which have been described for the first time almost twenty years ago and were immediately…”
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The chemoenzymatic synthesis of glycan-terminated oligo(Leu)x by Black, Sarah P., Liu, Melinda, Castillo, Cesar, Coradeli, Wynne, Totsingan, Filbert, Edson, Cody B., Khare, Sagar D., Gross, Richard A.

“…Introduction: Glycopeptides contain carbohydrate moieties (glycans) covalently attached to the side chain and/or terminal peptide units. Since glycans are…”
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Protease-Catalyzed l‑Aspartate Oligomerization: Substrate Selectivity and Computational Modeling by Yang, Fan, Totsingan, Filbert, Dolan, Elliott, Khare, Sagar D, Gross, Richard A

“…Poly­(aspartic acid) (PAA) is a biodegradable water-soluble anionic polymer that can potentially replace poly­(acrylic acid) for industrial applications and…”
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Peptide nucleic acids with a structurally biased backbone: effects of conformational constraints and stereochemistry by Corradini, Roberto, Sforza, Stefano, Tedeschi, Tullia, Totsingan, Filbert, Marchelli, Rosangela

“…Peptide nucleic acids (PNAs) are polyamidic oligonucleotide analogs which have been described for the first time fifteen years ago and were immediately found…”
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Conformational Heterogeneity in PNA:PNA Duplexes by Totsingan, Filbert, Jain, Vipul, Bracken, W. Clay, Faccini, Andrea, Tedeschi, Tullia, Marchelli, Rosangela, Corradini, Roberto, Kallenbach, Neville R, Green, Mark M

“…Oligomers of PNA:PNA duplexes with different amino acids appended to one strand of each duplex have been synthesized and studied for their chiral optical…”
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Highly selective single nucleotide polymorphism recogniton by a chiral (5S) PNA beacon by Totsingan, Filbert, Tedeschi, Tullia, Sforza, Stefano, Corradini, Roberto, Marchelli, Rosangela

“…A chiral peptide nucleic acid (PNA) beacon containing a C‐5 modified monomer based on L‐lysine was synthesized. The terminal amino group of the lysine side…”
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Supporting data for the characterization of PNA–DNA four-way junctions by Iverson, Douglas, Serrano, Crystal, Brahan, Ann Marie, Shams, Arik, Totsingan, Filbert, Bell, Anthony J.

“…Holliday or DNA four-way junctions (4WJs) are cruciform/bent structures composed of four DNA duplexes. 4WJs are key intermediates in homologous genetic…”
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Helix control in polymers: case of peptide nucleic acids (PNAs) by Totsingan, Filbert, Jain, Vipul, Green, Mark M

“…The helix is a critical conformation exhibited by biological macromolecules and plays a key role in fundamental biological processes. Biological helical…”
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Synthetic dendrimeric peptide active against biofilm and persister cells of Pseudomonas aeruginosa by Bahar, Ali Adem, Liu, Zhigang, Totsingan, Filbert, Buitrago, Carlos, Kallenbach, Neville, Ren, Dacheng

“…Antimicrobial dendrimeric peptides (AMDP) are a relatively new class of agents displaying repetitive functional groups on a branched core. Previously, we have…”
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Monomer Choice Influences N‑Acryloyl Amino Acid Grafter Conversion via Protease Catalysis by Edson, Cody B., Liu, Melinda, Totsingan, Filbert, O’Berg, Evan, Salvucci, John, Dao, Uyen, Khare, Sagar D., Gross, Richard A.

“…End-capped peptides modified with reactive functional groups on the N-terminus provide a route to prepare peptide–polymer conjugates for a broad range of…”
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Self-Assembly-Assisted Kinetically Controlled Papain-Catalyzed Formation of mPEG‑b‑Phe(Leu) x by Centore, Robert, Totsingan, Filbert, Amason, Anna-Christina, Lyons, Samantha, Zha, R. Helen, Gross, Richard A

“…Self-assembling peptide materials are promising next-generation materials with applications that include tissue engineering scaffolds, drug delivery,…”
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Therapeutic Efficacy of Lactonic Sophorolipids: Nanoceria-Assisted Combination Therapy of NSCLC using HDAC and Hsp90 Inhibitors by Naz, Shuguftha, Banerjee, Tuhina, Totsingan, Filbert, Woody, Kalee, Gross, Richard A, Santra, Santimukul

“…Non-Small-Cell Lung Cancer (NSCLC) has gained resistance to common chemo- and radiotherapy due to the oncogenic K-RAS mutations. In this work, lactonic…”
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Interaction of HMG proteins and H1 with hybrid PNA–DNA junctions by Totsingan, Filbert, Bell, Anthony J.

“…The objective of this study was to evaluate the effects of inserting peptide nucleic acid (PNA) sequences into the protein‐binding surface of an immobilized…”
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Peptide Modified Electrospun Glycopolymer Fibers by Fiorani, Andrea, Totsingan, Filbert, Pollicino, Antonio, Peng, Yifeng, Focarete, Maria Letizia, Gross, Richard A., Scandola, Mariastella

“…Oligo(Glu70‐co‐Leu30), a peptide synthesized by protease catalysis, is functionalized at the N‐terminus with a 4‐pentenoyl unit and grafted to…”
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Molecularly Engineered Surfactin Analogues Induce Nonapoptotic-Like Cell Death and Increased Selectivity in Multiple Breast Cancer Cell Types by Miceli, Rebecca T., Totsingan, Filbert, Naina, Tasnim, Islam, Samita, Dordick, Jonathan S., Corr, David T., Gross, Richard A.

“…Surfactin, a negatively charged amphiphilic lipopeptide biosurfactant, is synthesized by the bacterium Bacillus subtilis. It consists of a cyclic heptapeptide…”
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Sophorolipids: Expanding structural diversity by ring-opening cross-metathesis by Peng, Yifeng, Totsingan, Filbert, Meier, Michael A. R., Steinmann, Mark, Wurm, Frederik, Koh, Amanda, Gross, Richard A.

“…Lactonic sophorolipids (LSL) are glycolipid biosurfactants produced in large quantity by yeast fermentation. Chemical or enzymatic modification of naturally…”
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Characterization of the structural and protein recognition properties of hybrid PNA–DNA four-way junctions by Iverson, Douglas, Serrano, Crystal, Brahan, Ann Marie, Shams, Arik, Totsingan, Filbert, Bell, Anthony J.

“…The objective of this study is to evaluate the structure and protein recognition properties of hybrid four-way junctions (4WJs) composed of DNA and peptide…”
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Impact of Select Sophorolipid Derivatives on Macrophage Polarization and Viability by Diaz-Rodriguez, Patricia, Chen, Hongyu, Erndt-Marino, Joshua D, Liu, Fei, Totsingan, Filbert, Gross, Richard A, Hahn, Mariah S

“…A major limitation of many biomaterials is the induction of a host response that challenges the integrity and overall efficacy of the implanted material…”
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Sophorolipid Butyl Ester Diacetate Does Not Affect Macrophage Polarization but Enhances Astrocytic Glial Fibrillary Acidic Protein Expression at Micromolar Concentrations in Vitro by Ziemba, Alexis M, Gottipati, Manoj K, Totsingan, Filbert, Hanes, Cheryl M, Gross, Richard A, Lennartz, Michelle R, Gilbert, Ryan J

“…Peritoneal macrophages (PMACs) and spinal cord astrocytes were exposed to varying concentrations of soluble sophorolipid butyl ester diacetate (SLBEDA) in…”
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