Search Results - "Toth, Istvan"
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Peptide-based synthetic vaccines
Published in Chemical science (Cambridge) (01-01-2016)“…Classically all vaccines were produced using live or attenuated microorganisms or parts of them. However, the use of whole organisms, their components or the…”
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Modern Subunit Vaccines: Development, Components, and Research Opportunities
Published in ChemMedChem (01-03-2013)“…Traditional vaccines, based on the administration of killed or attenuated microorganisms, have proven to be among the most effective methods for disease…”
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3
Is Self-Compassion Universal? Support for the Measurement Invariance of the Self-Compassion Scale Across Populations
Published in Assessment (Odessa, Fla.) (01-01-2021)“…The Self-Compassion Scale (SCS) is a widely used measure to assess the trait of self-compassion, and, so far, it has been implicitly assumed that it functions…”
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4
Glycosylation, an effective synthetic strategy to improve the bioavailability of therapeutic peptides
Published in Chemical science (Cambridge) (01-01-2016)“…Glycosylation of peptides is a promising strategy for modulating the physicochemical properties of peptide drugs and for improving their absorption through…”
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5
The application of self-assembled nanostructures in peptide-based subunit vaccine development
Published in European polymer journal (01-08-2017)“…[Display omitted] •Smaller polymer-peptide conjugates-based nanoparticles are often more immunogenic.•Lipid-antigen conjugates-based nanoparticles can interact…”
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6
Chemical methods for peptide and protein production
Published in Molecules (12-04-2013)“…Since the invention of solid phase synthetic methods by Merrifield in 1963, the number of research groups focusing on peptide synthesis has grown…”
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Nanoparticle-induced unfolding of fibrinogen promotes Mac-1 receptor activation and inflammation
Published in Nature nanotechnology (01-01-2011)“…The chemical composition, size, shape and surface characteristics of nanoparticles affect the way proteins bind to these particles, and this in turn influences…”
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A Global Review on Short Peptides: Frontiers and Perspectives
Published in Molecules (Basel, Switzerland) (15-01-2021)“…Peptides are fragments of proteins that carry out biological functions. They act as signaling entities via all domains of life and interfere with…”
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An Illustration of the Exploratory Structural Equation Modeling (ESEM) Framework on the Passion Scale
Published in Frontiers in psychology (07-11-2017)“…While exploratory factor analysis (EFA) provides a more realistic presentation of the data with the allowance of item cross-loadings, confirmatory factor…”
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10
Carbohydrate Immune Adjuvants in Subunit Vaccines
Published in Pharmaceutics (14-10-2020)“…Modern subunit vaccines are composed of antigens and a delivery system and/or adjuvant (immune stimulator) that triggers the desired immune responses…”
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11
Refractometric sensing with plasmon resonances in dimer, trimer and quadrumer ensembles of gold nanoparticles
Published in EPJ Web of conferences (2024)“…We studied by FDTD computer simulations the dependence of the surface plasmon resonances in linearly arranged gold nanospheres on incident light polarization,…”
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Multifaceted Domino Knoevenagel‐Cyclization Reactions; Four Movements for 2H‐Chromenes and Chromans
Published in Advanced synthesis & catalysis (13-10-2023)“…Domino Knoevenagel‐cyclization reactions of 2H‐chromene and chroman derivatives containing o‐formylaryl amine or ether side‐chain was carried out to produce…”
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13
Peptide-based subunit nanovaccines
Published in Current drug delivery (01-05-2011)“…Classical vaccines incorporating live or attenuated microorganisms possess several disadvantages and cannot be applied against cancer and some pathogens…”
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14
TRPA1 up‐regulation mediates oxidative stress in a pulpitis model in vitro
Published in British journal of pharmacology (01-09-2024)“…Background and Purpose Pulpitis is associated with tooth hypersensitivity and results in pulpal damage. Thermosensitive transient receptor potential (TRP) ion…”
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Opening of an alternative ion permeation pathway in a nociceptor TRP channel
Published in Nature chemical biology (01-03-2014)“…Besides the canonical pore that allows passage of cations into the cell, the TRPM3 channel has an alternative ‘omega’ permeation pathway formed by the S1–S4…”
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Chemical Conjugation Strategies for the Development of Protein-Based Subunit Nanovaccines
Published in Vaccines (Basel) (28-05-2021)“…The production of subunit nanovaccines relies heavily on the development of a vaccine delivery system that is safe and efficient at delivering antigens to the…”
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Towards the Development of Synthetic Antibiotics: Designs Inspired by Natural Antimicrobial Peptides
Published in Current medicinal chemistry (01-12-2016)“…Virtually every living organism produces gene-encoded antimicrobial peptides (AMPs) that provide an immediate defence against pathogen invasion. Many AMPs have…”
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On the Importance of Balanced Need Fulfillment: A Person-Centered Perspective
Published in Journal of happiness studies (01-08-2020)“…Self-determination theory proposes that the fulfillment of the three basic psychological needs of autonomy, competence, and relatedness is important for…”
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Knoevenagel‐Cyclization Cascade Reactions of Substituted 5,6‐Dihydro‐2H‐Pyran Derivatives
Published in European journal of organic chemistry (07-12-2021)“…The diastereoselective domino‐Knoevenagel‐IMHDA reactions of 5,6‐dihydro‐2H‐pyran derivatives containing an o‐formylaryl amine or ether moiety were performed…”
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20
Investigation of bombesin peptide as a targeting ligand for the gastrin releasing peptide (GRP) receptor
Published in Bioorganic & medicinal chemistry (15-11-2016)“…Gastrin releasing peptide (GRP) receptor (GRPR), a bombesin family receptor, is overexpressed in many cancers including breast, prostate, pancreatic and lung…”
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