Search Results - "Toth, Daniel J."

Defining the subcellular distribution and metabolic channeling of phosphatidylinositol by Pemberton, Joshua G, Kim, Yeun Ju, Humpolickova, Jana, Eisenreichova, Andrea, Sengupta, Nivedita, Toth, Daniel J, Boura, Evzen, Balla, Tamas

“…Phosphatidylinositol (PI) is an essential structural component of eukaryotic membranes that also serves as the common precursor for polyphosphoinositide (PPIn)…”
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Lenz-Majewski mutations in PTDSS1 affect phosphatidylinositol 4-phosphate metabolism at ER-PM and ER-Golgi junctions by Sohn, Mira, Ivanova, Pavlina, Brown, H. Alex, Toth, Daniel J., Varnai, Peter, Kim, Yeun Ju, Balla, Tamas

“…Lenz-Majewski syndrome (LMS) is a rare disease characterized by complex craniofacial, dental, cutaneous, and limb abnormalities combined with intellectual…”
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Phosphatidylinositol 4,5‐bisphosphate controls Rab7 and PLEKMH1 membrane cycling during autophagosome–lysosome fusion by Baba, Takashi, Toth, Daniel J, Sengupta, Nivedita, Kim, Yeun Ju, Balla, Tamas

“…The small GTP ase Rab7 is a key organizer of receptor sorting and lysosomal degradation by recruiting of a variety of effectors depending on its GDP / GTP…”
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Phosphatidylinositol 4,5-bisphosphate controls Rab7 and PLEKMH1 membrane cycling during autophagosome-lysosome fusion by Baba, Takashi, Toth, Daniel J, Sengupta, Nivedita, Kim, Yeun Ju, Balla, Tamas

“…The small GTPase Rab7 is a key organizer of receptor sorting and lysosomal degradation by recruiting of a variety of effectors depending on its GDP/GTP-bound…”
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Phosphatidylinositol 4,5‐bisphosphate controls Rab7 and PLEKHM1 membrane cycling during autophagosome–lysosome fusion by Baba, Takashi, Toth, Daniel J, Sengupta, Nivedita, Kim, Yeun Ju, Balla, Tamas

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Monitoring Non-vesicular Transport of Phosphatidylserine and Phosphatidylinositol 4-Phosphate in Intact Cells by BRET Analysis by Sohn, Mira, Toth, Daniel J, Balla, Tamas

“…Non-vesicular lipid transport via lipid transfer proteins (LTPs) at membrane contact sites (MCSs) is critical for the maintenance of the lipid composition of…”
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Effect of hormone-induced plasma membrane phosphatidylinositol 4,5-bisphosphate depletion on receptor endocytosis suggests the importance of local regulation in phosphoinositide signaling by Tóth, Dániel J., Tóth, József T., Damouni, Amir, Hunyady, László, Várnai, Péter

“…Phosphatidylinositol 4,5-bisphosphate (PIP2) has been shown to be critical for the endocytosis of G protein-coupled receptors (GPCRs). We have previously…”
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Computational drug repurposing against SARS-CoV-2 reveals plasma membrane cholesterol depletion as key factor of antiviral drug activity by Barsi, Szilvia, Papp, Henrietta, Valdeolivas, Alberto, Tóth, Dániel J, Kuczmog, Anett, Madai, Mónika, Hunyady, László, Várnai, Péter, Saez-Rodriguez, Julio, Jakab, Ferenc, Szalai, Bence

“…Comparing SARS-CoV-2 infection-induced gene expression signatures to drug treatment-induced gene expression signatures is a promising bioinformatic tool to…”
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The Ubiquitin Ligase Adaptor NDFIP1 Interacts with TRESK and Negatively Regulates the Background K + Current by Pergel, Enikő, Tóth, Dániel J, Baukál, Dóra, Veres, Irén, Czirják, Gábor

“…The TRESK (K2P18.1, KCNK18) background potassium channel is expressed in primary sensory neurons and has been reported to contribute to the regulation of pain…”
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Visualization and Manipulation of Plasma Membrane-Endoplasmic Reticulum Contact Sites Indicates the Presence of Additional Molecular Components within the STIM1-Orai1 Complex by Várnai, Péter, Tóth, Balázs, Tóth, Dániel J., Hunyady, László, Balla, Tamas

“…STIM1, a recently identified endoplasmic reticulum (ER) protein, rapidly translocates to a plasma membrane-adjacent ER compartment upon depletion of the ER…”
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Quantifying lipid changes in various membrane compartments using lipid binding protein domains by Várnai, Péter, Gulyás, Gergő, Tóth, Dániel J, Sohn, Mira, Sengupta, Nivedita, Balla, Tamas

“…Graphical abstract…”
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Structural insights and in vitro reconstitution of membrane targeting and activation of human PI4KB by the ACBD3 protein by Klima, Martin, Tóth, Dániel J., Hexnerova, Rozalie, Baumlova, Adriana, Chalupska, Dominika, Tykvart, Jan, Rezabkova, Lenka, Sengupta, Nivedita, Man, Petr, Dubankova, Anna, Humpolickova, Jana, Nencka, Radim, Veverka, Vaclav, Balla, Tamas, Boura, Evzen

“…Phosphatidylinositol 4-kinase beta (PI4KB) is one of four human PI4K enzymes that generate phosphatidylinositol 4-phosphate (PI4P), a minor but essential…”
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Measurement of inositol 1,4,5-trisphosphate in living cells using an improved set of resonance energy transfer-based biosensors by Gulyás, Gergő, Tóth, József T, Tóth, Dániel J, Kurucz, István, Hunyady, László, Balla, Tamas, Várnai, Péter

“…Improved versions of inositol-1,4,5-trisphosphate (InsP3) sensors were created to follow intracellular InsP3 changes in single living cells and in cell…”
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BRET-monitoring of the dynamic changes of inositol lipid pools in living cells reveals a PKC-dependent PtdIns4P increase upon EGF and M3 receptor activation by Tóth, József T., Gulyás, Gergő, Tóth, Dániel J., Balla, András, Hammond, Gerald R.V., Hunyady, László, Balla, Tamás, Várnai, Péter

“…Deciphering many roles played by inositol lipids in signal transduction and membrane function demands experimental approaches that can detect their dynamic…”
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Acute depletion of plasma membrane phosphatidylinositol 4,5-bisphosphate impairs specific steps in endocytosis of the G-protein-coupled receptor by Tóth, Dániel J, Tóth, József T, Gulyás, Gergö, Balla, András, Balla, Tamas, Hunyady, László, Várnai, Péter

“…Receptor endocytosis plays an important role in regulating the responsiveness of cells to specific ligands. Phosphatidylinositol 4,5-bisphosphate…”
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Phosphatidylinositol 4,5‐bisphosphate controls Rab7 and PLEKHM 1 membrane cycling during autophagosome–lysosome fusion by Baba, Takashi, Toth, Daniel J, Sengupta, Nivedita, Kim, Yeun Ju, Balla, Tamas

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Erratum To: Phosphatidylinositol 4,5‐bisphosphate controls Rab7 and PLEKHM1 membrane cycling during autophagosome–lysosome fusion by Baba, Takashi, Toth, Daniel J, Sengupta, Nivedita, Kim, Yeun Ju, Balla, Tamas

“…Graphical Abstract…”
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Phosphatidylinositol 4,5‐bisphosphate controls Rab7 and PLEKHM 1 membrane cycling during autophagosome–lysosome fusion by Baba, Takashi, Toth, Daniel J, Sengupta, Nivedita, Kim, Yeun Ju, Balla, Tamas

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Phosphatidylinositol 4,5‐bisphosphate controls Rab7 and PLEKHM1 membrane cycling during autophagosome–lysosome fusion by Baba, Takashi, Toth, Daniel J, Sengupta, Nivedita, Kim, Yeun Ju, Balla, Tamas

“…The small GTPase Rab7 is a key organizer of receptor sorting and lysosomal degradation by recruiting of a variety of effectors depending on its GDP/GTP‐bound…”
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Mapping of the Localization of Type 1 Angiotensin Receptor in Membrane Microdomains Using Bioluminescence Resonance Energy Transfer-based Sensors by Balla, András, Tóth, Dániel J., Soltész-Katona, Eszter, Szakadáti, Gyöngyi, Erdélyi, László Sándor, Várnai, Péter, Hunyady, László

“…Initiation and termination of signaling of the type I angiotensin receptor (AT1-R) can lead to dynamic changes in its localization in plasma membrane…”
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