Search Results - "Totenhagen, John"

Quantitative magnetic resonance imaging of brain atrophy in a mouse model of Niemann-Pick type C disease by Totenhagen, John W, Bernstein, Adam, Yoshimaru, Eriko S, Erickson, Robert P, Trouard, Theodore P

“…In vivo magnetic resonance imaging (MRI) was used to investigate regional and global brain atrophy in the neurodegenerative Niemann Pick Type C1 (NPC1) disease…”
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A novel mouse model of Niemann-Pick type C disease carrying a D1005G-Npc1 mutation comparable to commonly observed human mutations by Maue, Robert A., Burgess, Robert W., Wang, Bing, Wooley, Christine M., Seburn, Kevin L., Vanier, Marie T., Rogers, Maximillian A., Chang, Catherine C., Chang, Ta-Yuan, Harris, Brent T., Graber, David J., Penatti, Carlos A.A., Porter, Donna M., Szwergold, Benjamin S., Henderson, Leslie P., Totenhagen, John W., Trouard, Theodore P., Borbon, Ivan A., Erickson, Robert P.

“…We have identified a point mutation in Npc1 that creates a novel mouse model (Npc1nmf164 ) of Niemann-Pick type C1 (NPC) disease: a single nucleotide change (A…”
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Author Correction: The effect of endothelial nitric oxide synthase on the hemodynamics and wall mechanics in murine arteriovenous fistulas by Pike, Daniel, Shiu, Yan-Ting, Cho, Yun-Fang, Le, Ha, Somarathna, Maheshika, Isayeva, Tatyana, Guo, Lingling, Symons, J. David, Kevil, Christopher G., Totenhagen, John, Lee, Timmy

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Analysis of Geometric and Hemodynamic Profiles in Rat Arteriovenous Fistula Following PDE5A Inhibition by Northrup, Hannah, Somarathna, Maheshika, Corless, Savanna, Falzon, Isabelle, Totenhagen, John, Lee, Timmy, Shiu, Yan-Ting

“…Arteriovenous fistula (AVF) is essential for chronic kidney disease (CKD) patients on hemodialysis, but treatment for AVF maturation failure remains an unmet…”
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High resolution hemodynamic profiling of murine arteriovenous fistula using magnetic resonance imaging and computational fluid dynamics by Pike, Daniel, Shiu, Yan-Ting, Somarathna, Maheshika, Guo, Lingling, Isayeva, Tatyana, Totenhagen, John, Lee, Timmy

“…Arteriovenous fistula (AVF) maturation failure remains a major cause of morbidity and mortality in hemodialysis patients. The two major etiologies of AVF…”
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Cdk5 drives formation of heterogeneous pancreatic neuroendocrine tumors by Carter, Angela M., Kumar, Nilesh, Herring, Brendon, Tan, Chunfeng, Guenter, Rachael, Telange, Rahul, Howse, Wayne, Viol, Fabrice, McCaw, Tyler R., Bickerton, Hayden H., Gupta, Priyanka, Gillardon, Frank, Woltering, Eugene A., Dhall, Deepti, Totenhagen, John, Banerjee, Ronadip R., Kurian, Elizabeth M., Reddy, Sushanth, Chen, Herbert, Schrader, Joerg, Bart Rose, J., Mukhtar, M. Shahid, Bibb, James A.

“…Pancreatic neuroendocrine tumors (PanNETs) are a heterogeneous population of neoplasms that arise from hormone-secreting islet cells of the pancreas and have…”
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1H magnetic resonance spectroscopy of neurodegeneration in a mouse model of niemann-pick type C1 disease by Totenhagen, John W., Yoshimaru, Eriko S., Erickson, Robert P., Trouard, Theodore P.

“…Purpose: To evaluate brain metabolite levels as in vivo indicators of disease progression in a widely studied mouse model of Niemann‐Pick type C1 (NPC1)…”
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(1) H magnetic resonance spectroscopy of neurodegeneration in a mouse model of niemann-pick type C1 disease by Totenhagen, John W, Yoshimaru, Eriko S, Erickson, Robert P, Trouard, Theodore P

“…To evaluate brain metabolite levels as in vivo indicators of disease progression in a widely studied mouse model of Niemann-Pick type C1 (NPC1) disease with…”
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In vivo assessment of neurodegeneration in niemann-pick type C mice by quantitative T2 mapping and diffusion tensor imaging by Totenhagen, John W., Lope-Piedrafita, Silvia, Borbon, Ivan A., Yoshimaru, Eriko S., Erickson, Robert P., Trouard, Theodore P.

“…Purpose: To quantitatively and noninvasively assess neurological disease progression in a mouse model of Niemann‐Pick type C (NPC) disease by measuring white…”
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Dynamic contrast enhanced magnetic resonance imaging of an orthotopic pancreatic cancer mouse model by Kim, Hyunki, Samuel, Sharon, Totenhagen, John W, Warren, Marie, Sellers, Jeffrey C, Buchsbaum, Donald J

“…Dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) has been limitedly used for orthotopic pancreatic tumor xenografts due to severe respiratory…”
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MRI detects therapeutic effects in weanling Niemann-Pick type C mice by Lope-Piedrafita, Silvia, Totenhagen, John W., Hicks, Chad M., Erickson, Robert P., Trouard, Theodore P.

“…To noninvasively evaluate the early effects of Niemann‐Pick type C (NPC) disease, diffusion tensor imaging (DTI) was carried out in the brains of very young…”
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RORγt-Expressing Pathogenic CD4 + T Cells Cause Brain Inflammation during Chronic Colitis by Mickael, Michel Edwar, Bhaumik, Suniti, Chakraborti, Ayanabha, Umfress, Alan A, van Groen, Thomas, Macaluso, Matthew, Totenhagen, John, Sorace, Anna G, Bibb, James A, Standaert, David G, Basu, Rajatava

“…Neurobehavioral disorders and brain abnormalities have been extensively reported in both Crohn's disease and ulcerative colitis patients. However, the…”
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Ultrathin Iron Oxide Nanowhiskers as Positive Contrast Agents for Magnetic Resonance Imaging by Macher, Thomas, Totenhagen, John, Sherwood, Jennifer, Qin, Ying, Gurler, Demet, Bolding, Mark S., Bao, Yuping

“…In this paper, a highly innovative concept of using ultrathin iron oxide nanowhiskers as a positive (T1) contrast agent for magnetic resonance imaging (MRI) is…”
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Nitric oxide releasing nanomatrix gel treatment inhibits venous intimal hyperplasia and improves vascular remodeling in a rodent arteriovenous fistula by Somarathna, Maheshika, Hwang, Patrick TJ, Millican, Reid C., Alexander, Grant C., Isayeva-Waldrop, Tatyana, Sherwood, Jennifer A., Brott, Brigitta C., Falzon, Isabelle, Northrup, Hannah, Shiu, Yan-Ting, Stubben, Chris J., Totenhagen, John, Jun, Ho-Wook, Lee, Timmy

“…Vascular access is the lifeline for hemodialysis patients and the single most important component of the hemodialysis procedure. Arteriovenous fistula (AVF) is…”
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Genetic impairment of succinate metabolism disrupts bioenergetic sensing in adrenal neuroendocrine cancer by Gupta, Priyanka, Strange, Keehn, Telange, Rahul, Guo, Ailan, Hatch, Heather, Sobh, Amin, Elie, Jonathan, Carter, Angela M., Totenhagen, John, Tan, Chunfeng, Sonawane, Yogesh A., Neuzil, Jiri, Natarajan, Amarnath, Ovens, Ashley J., Oakhill, Jonathan S., Wiederhold, Thorsten, Pacak, Karel, Ghayee, Hans K., Meijer, Laurent, Reddy, Sushanth, Bibb, James A.

“…Metabolic dysfunction mutations can impair energy sensing and cause cancer. Loss of function of the mitochondrial tricarboxylic acid (TCA) cycle enzyme subunit…”
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The effect of endothelial nitric oxide synthase on the hemodynamics and wall mechanics in murine arteriovenous fistulas by Pike, Daniel, Shiu, Yan-Ting, Cho, Yun-Fang, Le, Ha, Somarathna, Maheshika, Isayeva, Tatyana, Guo, Lingling, Symons, J. David, Kevil, Christopher G., Totenhagen, John, Lee, Timmy

“…Creation of a hemodialysis arteriovenous fistula (AVF) causes aberrant vascular mechanics at and near the AVF anastomosis. When inadequately regulated, these…”
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Design, manufacture, and analysis of customized phantoms for enhanced quality control in small animal MRI systems by Yoshimaru, Eriko, Totenhagen, John, Alexander, Gene E., Trouard, Theodore P.

“…Purpose Magnetic resonance imaging (MRI) is widely used in human brain research to evaluate the effects of healthy aging and development, as well as…”
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The geometry of arteriovenous fistulas using endothelial nitric oxide synthase mouse models by Falzon, Isabelle, Northrup, Hannah, Guo, Lingling, Totenhagen, John, Lee, Timmy, Shiu, Yan-Ting

“…Arteriovenous fistula (AVF) maturation failure is a significant clinical problem in the hemodialysis population. Geometric parameters of human AVFs were…”
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A novel mouse model of Niemann–Pick type C disease carrying a D1005G-Npc1 mutation comparable to commonly observed human mutations by Maue, Robert A., Burgess, Robert W., Wang, Bing, Wooley, Christine M., Seburn, Kevin L., Vanier, Marie T., Rogers, Maximillian A., Chang, Catherine C., Chang, Ta-Yuan, Harris, Brent T., Graber, David J., Penatti, Carlos A.A., Porter, Donna M., Szwergold, Benjamin S., Henderson, Leslie P., Totenhagen, John W., Trouard, Theodore P., Borbon, Ivan A., Erickson, Robert P.

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Correction to: High resolution hemodynamic profiling of murine arteriovenous fistula using magnetic resonance imaging and computational fluid dynamics by Pike, Daniel, Shiu, Yan-Ting, Somarathna, Maheshika, Guo, Lingling, Isayeva, Tatyana, Totenhagen, John, Lee, Timmy

“…After publication of the original article…”
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