Search Results - "Tossing, Gilles"
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Fatty acids derived from the probiotic Lacticaseibacillus rhamnosus HA-114 suppress age-dependent neurodegeneration
Published in Communications biology (07-12-2022)“…The human microbiota is believed to influence health. Microbiome dysbiosis may be linked to neurological conditions like Alzheimer’s disease, amyotrophic…”
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Genetic and pharmacological PARP inhibition reduces axonal degeneration in C. elegans models of ALS
Published in Human molecular genetics (29-09-2022)“…Axonal degeneration is observed in early stages of several neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). This degeneration…”
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ATP6V0C variants impair V-ATPase function causing a neurodevelopmental disorder often associated with epilepsy
Published in Brain (London, England : 1878) (19-04-2023)“…Abstract The vacuolar H+-ATPase is an enzymatic complex that functions in an ATP-dependent manner to pump protons across membranes and acidify organelles,…”
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A single copy transgenic mutant FUS strain reproduces age-dependent ALS phenotypes in C. elegans
Published in microPublication biology (01-01-2021)“…Mutations in the human DNA/RNA binding protein FUS are associated with amyotrophic lateral sclerosis and frontotemporal lobar degeneration, including some…”
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