Search Results - "Tossavainen, Helena"

Arabidopsis RCD1 coordinates chloroplast and mitochondrial functions through interaction with ANAC transcription factors by Shapiguzov, Alexey, Vainonen, Julia P, Hunter, Kerri, Tossavainen, Helena, Tiwari, Arjun, Järvi, Sari, Hellman, Maarit, Aarabi, Fayezeh, Alseekh, Saleh, Wybouw, Brecht, Van Der Kelen, Katrien, Nikkanen, Lauri, Krasensky-Wrzaczek, Julia, Sipari, Nina, Keinänen, Markku, Tyystjärvi, Esa, Rintamäki, Eevi, De Rybel, Bert, Salojärvi, Jarkko, Van Breusegem, Frank, Fernie, Alisdair R, Brosché, Mikael, Permi, Perttu, Aro, Eva-Mari, Wrzaczek, Michael, Kangasjärvi, Jaakko

“…Reactive oxygen species (ROS)-dependent signaling pathways from chloroplasts and mitochondria merge at the nuclear protein RADICAL-INDUCED CELL DEATH1 (RCD1)…”
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HACANCOi: a new Hα-detected experiment for backbone resonance assignment of intrinsically disordered proteins by Karjalainen, Mikael, Tossavainen, Helena, Hellman, Maarit, Permi, Perttu

“…Unidirectional coherence transfer is highly efficient in intrinsically disordered proteins (IDPs). Their elevated ps-ns timescale dynamics ensures long…”
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Reassessing the substrate specificities of the major Staphylococcus aureus peptidoglycan hydrolases lysostaphin and LytM by Antenucci, Lina, Virtanen, Salla, Thapa, Chandan, Jartti, Minne, Pitkänen, Ilona, Tossavainen, Helena, Permi, Perttu

“…Orchestrated action of peptidoglycan (PG) synthetases and hydrolases is vital for bacterial growth and viability. Although the function of several PG…”
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1H, 13C, and 15N NMR chemical shift assignment of LytM N-terminal domain (residues 26–184) by Pitkänen, Ilona, Tossavainen, Helena, Permi, Perttu

“…Antibiotic resistance is a growing problem and a global threat for modern healthcare. New approaches complementing the traditional antibiotic drugs are…”
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Evolutionary plasticity of SH3 domain binding by Nef proteins of the HIV-1/SIVcpz lentiviral lineage by Zhao, Zhe, Fagerlund, Riku, Tossavainen, Helena, Hopfensperger, Kristina, Lotke, Rishikesh, Srinivasachar Badarinarayan, Smitha, Kirchhoff, Frank, Permi, Perttu, Sato, Kei, Sauter, Daniel, Saksela, Kalle

“…The accessory protein Nef of human and simian immunodeficiency viruses (HIV and SIV) is an important pathogenicity factor known to interact with cellular…”
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Dispersion from Cα or NH: 4D experiments for backbone resonance assignment of intrinsically disordered proteins by Tossavainen, Helena, Salovaara, Santeri, Hellman, Maarit, Ihalin, Riikka, Permi, Perttu

“…Resonance assignment of intrinsically disordered proteins is remarkably challenging due to scant chemical shift dispersion arising from conformational…”
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Identification and structural characterization of LytU, a unique peptidoglycan endopeptidase from the lysostaphin family by Raulinaitis, Vytas, Tossavainen, Helena, Aitio, Olli, Juuti, Jarmo T., Hiramatsu, Keiichi, Kontinen, Vesa, Permi, Perttu

“…We introduce LytU, a short member of the lysostaphin family of zinc-dependent pentaglycine endopeptidases. It is a potential antimicrobial agent for S. aureus…”
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Chemical shift assignments of the catalytic domain of Staphylococcus aureus LytM by Tossavainen, Helena, Pitkänen, Ilona, Antenucci, Lina, Thapa, Chandan, Permi, Perttu

“…S. aureus resistance to antibiotics has increased rapidly. MRSA strains can simultaneously be resistant to many different classes of antibiotics, including the…”
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1H, 13C, and 15N NMR chemical shift assignment of the complex formed by the first EPEC EspF repeat and N-WASP GTPase binding domain by Karjalainen, Mikael, Hellman, Maarit, Tossavainen, Helena, Permi, Perttu

“…LEE-encoded effector EspF (EspF) is an effector protein part of enteropathogenic Escherichia coli ’s (EPEC’s) arsenal for intestinal infection. This…”
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Structural and Functional Insights Into Lysostaphin-Substrate Interaction by Tossavainen, Helena, Raulinaitis, Vytas, Kauppinen, Linda, Pentikäinen, Ulla, Maaheimo, Hannu, Permi, Perttu

“…Lysostaphin from and its family enzymes rapidly acquire prominence as the next generation agents in treatment of infections. The specificity of lysostaphin is…”
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Flexible Structure of Peptide-Bound Filamin A Mechanosensor Domain Pair 20-21 by Seppälä, Jonne, Tossavainen, Helena, Rodic, Nebojsa, Permi, Perttu, Pentikäinen, Ulla, Ylänne, Jari

“…Filamins (FLNs) are large, multidomain actin cross-linking proteins with diverse functions. Besides regulating the actin cytoskeleton, they serve as important…”
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Decreased temperature increases the expression of a disordered bacterial late embryogenesis abundant (LEA) protein that enhances natural transformation by Maula, Terhi, Vahvelainen, Nelli, Tossavainen, Helena, Koivunen, Tuuli, T. Pöllänen, Marja, Johansson, Anders, Permi, Perttu, Ihalin, Riikka

“…Late embryogenesis abundant (LEA) proteins are important players in the management of responses to stressful conditions, such as drought, high salinity, and…”
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Characterization of intrinsically disordered prostate associated gene (PAGE5) at single residue resolution by NMR spectroscopy by Hellman, Maarit, Tossavainen, Helena, Rappu, Pekka, Heino, Jyrki, Permi, Perttu

“…The Cancer-Testis antigens (CTA) are proteins expressed in human germ line and certain cancer cells. CTAs form a large gene family, representing 10% of…”
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Model of a Six Immunoglobulin-Like Domain Fragment of Filamin A (16–21) Built Using Residual Dipolar Couplings by Tossavainen, Helena, Koskela, Outi, Jiang, Pengju, Ylänne, Jari, Campbell, Iain D., Kilpeläinen, Ilkka, Permi, Perttu

“…Filamins are actin-binding proteins that participate in a wide range of cell functions, including cell morphology, locomotion, membrane protein localization,…”
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Structural Basis of PxxDY Motif Recognition in SH3 Binding by Aitio, Olli, Hellman, Maarit, Kesti, Tapio, Kleino, Iivari, Samuilova, Olga, Pääkkönen, Kimmo, Tossavainen, Helena, Saksela, Kalle, Permi, Perttu

“…We have determined the solution structure of epidermal growth factor receptor pathway substrate 8 (Eps8) L1 Src homology 3 (SH3) domain in complex with the…”
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Chimeric Avidin--NMR structure and dynamics of a 56 kDa homotetrameric thermostable protein by Tossavainen, Helena, Kukkurainen, Sampo, Määttä, Juha A E, Kähkönen, Niklas, Pihlajamaa, Tero, Hytönen, Vesa P, Kulomaa, Markku S, Permi, Perttu

“…Chimeric avidin (ChiAVD) is a product of rational protein engineering remarkably resistant to heat and harsh conditions. In quest of the fundamentals behind…”
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Solution structures of the first and fourth TSR domains of F-spondin by Pääkkönen, Kimmo, Tossavainen, Helena, Permi, Perttu, Rakkolainen, Harri, Rauvala, Heikki, Raulo, Erkki, Kilpeläinen, Ilkka, Güntert, Peter

“…F‐spondin is a protein mainly associated with neuronal development. It attaches to the extracellular matrix and acts in the axon guidance of the developing…”
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Crystal Structure of the N-terminal NC4 Domain of Collagen IX, a Zinc Binding Member of the Laminin-Neurexin-Sex Hormone Binding Globulin (LNS) Domain Family by Leppaönen, Veli-Matti, Tossavainen, Helena, Permi, Perttu, Lehtioö, Lari, Roönnholm, Gunilla, Goldman, Adrian, Kilpelaiönen, Ilkka, Pihlajamaa, Tero

“…Collagen IX, located on the surface of collagen fibrils, is crucial for cartilage integrity and stability. The N-terminal NC4 domain of the α1(IX) chain is…”
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Structural Basis of the High Affinity Interaction between the Alphavirus Nonstructural Protein-3 (nsP3) and the SH3 Domain of Amphiphysin-2 by Tossavainen, Helena, Aitio, Olli, Hellman, Maarit, Saksela, Kalle, Permi, Perttu

“…We show that a peptide from Chikungunya virus nsP3 protein spanning residues 1728–1744 binds the amphiphysin-2 (BIN1) Src homology-3 (SH3) domain with an…”
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Dispersion from C α or N H : 4D experiments for backbone resonance assignment of intrinsically disordered proteins by Tossavainen, Helena, Salovaara, Santeri, Hellman, Maarit, Ihalin, Riikka, Permi, Perttu

“…Resonance assignment of intrinsically disordered proteins is remarkably challenging due to scant chemical shift dispersion arising from conformational…”
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