Search Results - "Toshiyuki Ohtsuka"

Dynamic control of neural stem cells by bHLH factors by Kageyama, Ryoichiro, Shimojo, Hiromi, Ohtsuka, Toshiyuki

“…•Oscillatory expression of multiple bHLH factors in neural stem cells.•Activation of neural stem cell proliferation by Ascl1 and Hes1 oscillations.•Cell fate…”
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Hes1 overexpression leads to expansion of embryonic neural stem cell pool and stem cell reservoir in the postnatal brain by Ohtsuka, Toshiyuki, Kageyama, Ryoichiro

“…Neural stem cells (NSCs) gradually alter their characteristics during mammalian neocortical development, resulting in the production of various neurons and…”
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A continuation/GMRES method for fast computation of nonlinear receding horizon control by Ohtsuka, Toshiyuki

“…In this paper, a fast numerical algorithm for nonlinear receding horizon control is proposed. The control input is updated by a differential equation to trace…”
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Regulation of temporal properties of neural stem cells and transition timing of neurogenesis and gliogenesis during mammalian neocortical development by Ohtsuka, Toshiyuki, Kageyama, Ryoichiro

“…In the developing mammalian neocortex, neural stem cells (NSCs) gradually alter their characteristics as development proceeds. NSCs initially expand the…”
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Oscillations in Notch Signaling Regulate Maintenance of Neural Progenitors by Shimojo, Hiromi, Ohtsuka, Toshiyuki, Kageyama, Ryoichiro

“…Expression of the Notch effector gene Hes1 is required for maintenance of neural progenitors in the embryonic brain, but persistent and high levels of Hes1…”
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Output‐feedback stochastic model predictive control of chance‐constrained nonlinear systems by Zhang, Jingyu, Ohtsuka, Toshiyuki

“…This study covers the output‐feedback model predictive control (MPC) of nonlinear systems subjected to stochastic disturbances and state chance constraints…”
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Dual activation of Shh and Notch signaling induces dramatic enlargement of neocortical surface area by Ohtsuka, Toshiyuki, Kageyama, Ryoichiro

“…•hSmoM2-overexpressing Tg mice exhibited an enlarged neocortex.•Dual activation of Shh and Notch signaling enhanced the neocortical expansion.•hSmoM2/Hes…”
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The Hes gene family: repressors and oscillators that orchestrate embryogenesis by Kageyama, Ryoichiro, Ohtsuka, Toshiyuki, Kobayashi, Taeko

“…Embryogenesis involves orchestrated processes of cell proliferation and differentiation. The mammalian Hes basic helix-loop-helix repressor genes play central…”
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Dynamic Notch signaling in neural progenitor cells and a revised view of lateral inhibition by Kageyama, Ryoichiro, Ohtsuka, Toshiyuki, Shimojo, Hiromi, Imayoshi, Itaru

“…In a process termed lateral inhibition, nascent neurons via expression of Notch ligands are thought to suppress neuronal development of adjacent cells. It has…”
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Nonlinear Eigenvalue Approach to Differential Riccati Equations for Contraction Analysis by Kawano, Yu, Ohtsuka, Toshiyuki

“…In this paper, we extend the eigenvalue method of the algebraic Riccati equation to the differential Riccati equation (DRE) in contraction analysis. One of the…”
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Hes5 regulates the transition timing of neurogenesis and gliogenesis in mammalian neocortical development by Bansod, Shama, Kageyama, Ryoichiro, Ohtsuka, Toshiyuki

“…During mammalian neocortical development, neural stem/progenitor cells (NSCs) sequentially give rise to deep layer neurons and superficial layer neurons…”
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Stemflow hydrology and DOM flux in relation to tree size and rainfall event characteristics by Chen, Siyu, Cao, Ruoming, Yoshitake, Shinpei, Ohtsuka, Toshiyuki

“…•A study of stemflow based on more than 100 individual rainfall events.•Tree size effect on stemflow production varied under different rainfall intensity.•Tree…”
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Oscillatory control of Delta-like1 in cell interactions regulates dynamic gene expression and tissue morphogenesis by Shimojo, Hiromi, Isomura, Akihiro, Ohtsuka, Toshiyuki, Kori, Hiroshi, Miyachi, Hitoshi, Kageyama, Ryoichiro

“…Notch signaling regulates tissue morphogenesis through cell-cell interactions. The Notch effectors Hes1 and Hes7 are expressed in an oscillatory manner and…”
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Sonic hedgehog expands neural stem cells in the neocortical region leading to an expanded and wrinkled neocortical surface by Shqirat, Mohammed, Kinoshita, Akira, Kageyama, Ryoichiro, Ohtsuka, Toshiyuki

“…An expanded and folded neocortex is characteristic of higher mammals, including humans and other primates. The neocortical surface area was dramatically…”
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Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain by Ikeda, Toshio, Takao, Keizo, Mori, Kensaku, Itohara, Shigeyoshi, Kageyama, Ryoichiro, Sakamoto, Masayuki, Yamaguchi, Masahiro, Ohtsuka, Toshiyuki, Imayoshi, Itaru, Miyakawa, Tsuyoshi

“…How important is ongoing neurogenesis to the function of the adult brain? Using genetic labeling and ablation methods in mice, Imayoshi and colleagues show…”
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Modification of gene expression and soluble factor secretion in the lateral ventricle choroid plexus: Analysis of the impacts on the neocortical development by Kinoshita, Akira, Shqirat, Mohammed, Kageyama, Ryoichiro, Ohtsuka, Toshiyuki

“…•Two kinds of regulatory elements successfully directed expression of candidate genes in the ChP of the transgenic mice.•Overexpression of Shh in the CPECs led…”
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Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline by Imayoshi, Itaru, Shimogori, Tomomi, Ohtsuka, Toshiyuki, Kageyama, Ryoichiro

“…The choroid plexus in the brain is unique because it is a non-neural secretory tissue. It secretes the cerebrospinal fluid and functions as a blood-brain…”
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Automated loading of a hydraulic excavator using nonlinear model predictive control with preference-based calibration by Ishihara, Shinji, Ohtsuka, Toshiyuki

“…This study deals with the control methods for automating the operation of a hydraulic excavator loading soil onto the bed of a dump truck. The loading…”
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A recursive Riccati interior-point method for chance-constrained stochastic model predictive control by Zhang, Jingyu, Ohtsuka, Toshiyuki

“…This study covers the model predictive control of linear discrete-time systems subject to stochastic additive disturbances and state chance constraints. The…”
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High salinity leads to accumulation of soil organic carbon in mangrove soil by Kida, Morimaru, Tomotsune, Mitsutoshi, Iimura, Yasuo, Kinjo, Kazutoshi, Ohtsuka, Toshiyuki, Fujitake, Nobuhide

“…Although mangrove forests are one of the most well-known soil organic carbon (SOC) sinks, the mechanism underlying SOC accumulation is relatively unknown. High…”
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