Search Results - "Toshiyoshi Fujiwara"

Circular RNA ciRS-7-A Promising Prognostic Biomarker and a Potential Therapeutic Target in Colorectal Cancer by Weng, Wenhao, Wei, Qing, Toden, Shusuke, Yoshida, Kazuhiro, Nagasaka, Takeshi, Fujiwara, Toshiyoshi, Cai, Sanjun, Qin, Huanlong, Ma, Yanlei, Goel, Ajay

“…Colorectal cancer is one of the most common malignancies worldwide. Recently, a novel circular RNA, ciRS-7, was proposed to be a potential miR-7 sponge. As…”
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Understanding and exploiting hTERT promoter regulation for diagnosis and treatment of human cancers by Kyo, Satoru, Takakura, Masahiro, Fujiwara, Toshiyoshi, Inoue, Masaki

“…Telomerase activation is a critical step for human carcinogenesis through the maintenance of telomeres, but the activation mechanism during carcinogenesis…”
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Sarcopenia and Comorbidity in Gastric Cancer Surgery as a Useful Combined Factor to Predict Eventual Death from Other Causes by Kuwada, Kazuya, Kuroda, Shinji, Kikuchi, Satoru, Yoshida, Ryuichi, Nishizaki, Masahiko, Kagawa, Shunsuke, Fujiwara, Toshiyoshi

“…Background Sarcopenia is recognized as an important prognostic factor in various types of cancer, including gastric cancer. While long-term survival analyses…”
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Clinical Impact of Sarcopenia on Gastric Cancer by Kuwada, Kazuya, Kuroda, Shinji, Kikuchi, Satoru, Yoshida, Ryuichi, Nishizaki, Masahiko, Kagawa, Shunsuke, Fujiwara, Toshiyoshi

“…Sarcopenia is a complex syndrome defined by progressive and generalized loss of skeletal muscle mass and strength. Although sarcopenia is mainly associated…”
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Multidisciplinary oncolytic virotherapy for gastrointestinal cancer by Fujiwara, Toshiyoshi

“…Replication‐selective tumor‐specific viruses represent a novel approach for treating neoplastic diseases. These vectors are designed to induce virus‐mediated…”
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Fibroblast activation protein targeted near infrared photoimmunotherapy (NIR PIT) overcomes therapeutic resistance in human esophageal cancer by Katsube, Ryoichi, Noma, Kazuhiro, Ohara, Toshiaki, Nishiwaki, Noriyuki, Kobayashi, Teruki, Komoto, Satoshi, Sato, Hiroaki, Kashima, Hajime, Kato, Takuya, Kikuchi, Satoru, Tazawa, Hiroshi, Kagawa, Shunsuke, Shirakawa, Yasuhiro, Kobayashi, Hisataka, Fujiwara, Toshiyoshi

“…Cancer-associated fibroblasts (CAFs) have an important role in the tumor microenvironment. CAFs have the multifunctionality which strongly support cancer…”
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A Systematic Review of Minimally Invasive Versus Open Radical Antegrade Modular Pancreatosplenectomy for Pancreatic Cancer by Takagi, Kosei, Umeda, Yuzo, Yoshida, Ryuichi, Yagi, Takahito, Fujiwara, Toshiyoshi

“…The aim of this study was to investigate surgical and oncological outcomes of minimally invasive (MI) and open radical antegrade modular pancreatosplenectomy…”
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Novel evidence for a PIWI-interacting RNA (piRNA) as an oncogenic mediator of disease progression, and a potential prognostic biomarker in colorectal cancer by Weng, Wenhao, Liu, Na, Toiyama, Yuji, Kusunoki, Masato, Nagasaka, Takeshi, Fujiwara, Toshiyoshi, Wei, Qing, Qin, Huanlong, Lin, Haifan, Ma, Yanlei, Goel, Ajay

“…Emerging evidence suggests that PIWI-interacting RNAs (piRNAs) may be important epigenetic regulators of gene expression in human cancers; however, their…”
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Robotic Radical Antegrade Modular Pancreatosplenectomy Using the Supracolic Anterior Superior Mesenteric Artery Approach by Takagi, Kosei, Umeda, Yuzo, Yoshida, Ryuichi, Yagi, Takahito, Fujiwara, Toshiyoshi

“…Background Radical antegrade modular pancreatosplenectomy (RAMPS) is the standardized approach in open pancreatic resection for pancreatic body and tail…”
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Cancer‐associated fibroblasts (CAFs) promote the lymph node metastasis of esophageal squamous cell carcinoma by Kashima, Hajime, Noma, Kazuhiro, Ohara, Toshiaki, Kato, Takuya, Katsura, Yuki, Komoto, Satoshi, Sato, Hiroaki, Katsube, Ryoichi, Ninomiya, Takayuki, Tazawa, Hiroshi, Shirakawa, Yasuhiro, Fujiwara, Toshiyoshi

“…Lymph node metastasis is a pathognomonic feature of spreading tumors, and overcoming metastasis is a challenge in attaining more favorable clinical outcomes…”
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The PVT1 lncRNA is a novel epigenetic enhancer of MYC, and a promising risk-stratification biomarker in colorectal cancer by Shigeyasu, Kunitoshi, Toden, Shusuke, Ozawa, Tsuyoshi, Matsuyama, Takatoshi, Nagasaka, Takeshi, Ishikawa, Toshiaki, Sahoo, Debashis, Ghosh, Pradipta, Uetake, Hiroyuki, Fujiwara, Toshiyoshi, Goel, Ajay

“…Accumulating evidence suggests that dysregulation of transcriptional enhancers plays a significant role in cancer pathogenesis. Herein, we performed a…”
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Preoperative Controlling Nutritional Status (CONUT) Score for Assessment of Prognosis Following Hepatectomy for Hepatocellular Carcinoma by Takagi, Kosei, Yagi, Takahito, Umeda, Yuzo, Shinoura, Susumu, Yoshida, Ryuichi, Nobuoka, Daisuke, Kuise, Takashi, Araki, Hiroyuki, Fujiwara, Toshiyoshi

“…Background Immune-nutritional status has been recently reported as a prognostic factor in hepatocellular carcinoma (HCC). The controlling nutritional status…”
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Visualized Evaluation of Blood Flow to the Gastric Conduit and Complications in Esophageal Reconstruction by Noma, Kazuhiro, Shirakawa, Yasuhiro, Kanaya, Nobuhiko, Okada, Tsuyoshi, Maeda, Naoaki, Ninomiya, Takayuki, Tanabe, Shunsuke, Sakurama, Kazufumi, Fujiwara, Toshiyoshi

“…Evaluation of the blood supply to gastric conduits is critically important to avoid complications after esophagectomy. We began visual evaluation of blood flow…”
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Impact of Autophagy in Oncolytic Adenoviral Therapy for Cancer by Tazawa, Hiroshi, Kuroda, Shinji, Hasei, Joe, Kagawa, Shunsuke, Fujiwara, Toshiyoshi

“…Oncolytic virotherapy has recently emerged as a promising strategy for inducing tumor-specific cell death. Adenoviruses are widely and frequently used in…”
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Robotic isolated caudate-lobe liver resection using the caudal approach for giant hepatic hemangioma (with video) by Kondo, Ryutaro, Takagi, Kosei, Umeda, Yuzo, Fujiwara, Toshiyoshi

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The characteristics and outcomes of small bowel adenocarcinoma: a multicentre retrospective observational study by Sakae, Hiroyuki, Kanzaki, Hiromitsu, Nasu, Junichiro, Akimoto, Yutaka, Matsueda, Kazuhiro, Yoshioka, Masao, Nakagawa, Masahiro, Hori, Shinichiro, Inoue, Masafumi, Inaba, Tomoki, Imagawa, Atsushi, Takatani, Masahiro, Takenaka, Ryuta, Suzuki, Seiyu, Fujiwara, Toshiyoshi, Okada, Hiroyuki

“…Background: Small bowel adenocarcinoma (SBA) is a rare malignancy that accounts for 1–2% of gastrointestinal tumours. We investigated the clinical…”
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Telomerase-specific oncolytic immunotherapy for promoting efficacy of PD-1 blockade in osteosarcoma by Mochizuki, Yusuke, Tazawa, Hiroshi, Demiya, Koji, Kure, Miho, Kondo, Hiroya, Komatsubara, Tadashi, Sugiu, Kazuhisa, Hasei, Joe, Yoshida, Aki, Kunisada, Toshiyuki, Urata, Yasuo, Kagawa, Shunsuke, Ozaki, Toshifumi, Fujiwara, Toshiyoshi

“…Immune checkpoint inhibitors including anti-programmed cell death 1 (PD-1) antibody have recently improved clinical outcome in certain cancer patients;…”
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Prediction of Early Recurrence After Surgery for Liver Tumor (ERASL): An International Validation of the ERASL Risk Models by Beumer, Berend R., Takagi, Kosei, Vervoort, Bastiaan, Buettner, Stefan, Umeda, Yuzo, Yagi, Takahito, Fujiwara, Toshiyoshi, Steyerberg, Ewout W., IJzermans, Jan N. M.

“…Background This study aimed to assess the performance of the pre- and postoperative early recurrence after surgery for liver tumor (ERASL) models at external…”
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Impact of lymph node dissection on clinical outcomes of intrahepatic cholangiocarcinoma: Inverse probability of treatment weighting with survival analysis by Umeda, Yuzo, Mitsuhashi, Toshiharu, Kojima, Toru, Satoh, Daisuke, Sui, Kenta, Endo, Yoshikatsu, Inagaki, Masaru, Oishi, Masahiro, Yagi, Takahito, Fujiwara, Toshiyoshi

“…Background Lymph node metastasis (LNM) has been established as a critical risk factor for prognosis in intrahepatic cholangiocarcinoma (ICC). The clinical…”
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p53-armed oncolytic adenovirus induces autophagy and apoptosis in KRAS and BRAF-mutant colorectal cancer cells by Tamura, Shuta, Tazawa, Hiroshi, Hori, Naoto, Li, Yuncheng, Yamada, Motohiko, Kikuchi, Satoru, Kuroda, Shinji, Urata, Yasuo, Kagawa, Shunsuke, Fujiwara, Toshiyoshi

“…Colorectal cancer (CRC) cells harboring KRAS or BRAF mutations show a more-malignant phenotype than cells with wild-type KRAS and BRAF. KRAS/BRAF–wild-type…”
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