Search Results - "Toshihiko Yanase"

Reflections and expectations of an endocrinologist and diabetologist on the launch of a new, board-certified Endocrinology, Diabetes and Metabolism specialist system pioneered by the JES and the JDS by Yanase, Toshihiko

“…[Introduction] Hormones are produced by multiple organs in the body, circulate via the blood, and play essential roles in maintaining homeostasis throughout…”
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Frailty in elderly diabetes patients by Yanase, Toshihiko, Yanagita, Ikumi, Muta, Kazuo, Nawata, Hajime

“…Frailty is a state of vulnerability and a consequence of cumulative decline in multiple physiological systems over a lifespan. The occurrence of frailty…”
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A nationwide survey of adrenal incidentalomas in Japan: the first report of clinical and epidemiological features by Ichijo, Takamasa, Ueshiba, Hajime, Nawata, Hajime, Yanase, Toshihiko

“…The aim of this study was to reveal clear epidemiologic and clinical characteristics of incidentally discovered adrenal masses, termed adrenal incidentalomas…”
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SGLT2 inhibitor ipragliflozin attenuates breast cancer cell proliferation by Komatsu, Shiho, Nomiyama, Takashi, Numata, Tomohiro, Kawanami, Takako, Hamaguchi, Yuriko, Iwaya, Chikayo, Horikawa, Tsuyoshi, Fujimura-Tanaka, Yuki, Hamanoue, Nobuya, Motonaga, Ryoko, Tanabe, Makito, Inoue, Ryuji, Yanase, Toshihiko, Kawanami, Daiji

“…Cancer is currently one of the major causes of death in patients with type 2 diabetes mellitus. We previously reported the beneficial effects of the…”
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Comparison and commutability study between standardized liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS) and chemiluminescent enzyme immunoassay for aldosterone measurement in blood by Nishikawa, Tetsuo, Satoh, Fumitoshi, Takashi, Yuichi, Yanase, Toshihiko, Itoh, Hiroshi, Kurihara, Isao, Shibata, Hirotaka, Oki, Yutaka, Naruse, Mitsuhide, Sasamoto, Hidehiko, Kuwa, Katsuhiko

“…A commutability confirmation test for the blood aldosterone measurement was performed on liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS)…”
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New diagnostic criteria of adrenal subclinical Cushing’s syndrome: opinion from the Japan Endocrine Society by Yanase, Toshihiko, Oki, Yutaka, Katabami, Takuyuki, Otsuki, Michio, Kageyama, Kazunori, Tanaka, Tomoaki, Kawate, Hisaya, Tanabe, Makito, Doi, Masaru, Akehi, Yuko, Ichijo, Takamasa

“…New diagnostic criteria and the treatment policy for adrenal subclinical Cushing’s syndrome (SCS) are proposed on behalf of the Japan Endocrine Society. The…”
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Extension of Survival in Bilaterally Adrenalectomized Mice by Implantation of SF-1/Ad4BP-Induced Steroidogenic Cells by Tanaka, Tomoko, Aoyagi, Chikao, Mukai, Kuniaki, Nishimoto, Koshiro, Kodama, Shohta, Yanase, Toshihiko

“…Abstract Mesenchymal stroma/stem cells (MSCs) exist in adult tissues, such as adipose tissue and bone marrow, and differentiate into cells of multiple…”
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High-mobility group box 2 protein is essential for the early phase of adipogenesis by Morinaga, Hidetaka, Muta, Yoshimi, Tanaka, Tomoko, Tanabe, Makito, Hamaguchi, Yuriko, Yanase, Toshihiko

“…Understanding of the mechanism of adipogenesis is essential for the control of obesity, which predisposes toward numerous health problems. High-mobility group…”
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GLP-1 Receptor Agonist Exendin-4 Attenuates NR4A Orphan Nuclear Receptor NOR1 Expression in Vascular Smooth Muscle Cells by Takahashi, Hiroyuki, Nomiyama, Takashi, Terawaki, Yuichi, Kawanami, Takako, Hamaguchi, Yuriko, Tanaka, Tomoko, Tanabe, Makito, Bruemmer, Dennis, Yanase, Toshihiko

“…Aims: Recently, incretin therapy has attracted increasing attention because of its potential use in tissue-protective therapy. Neuron-derived orphan receptor 1…”
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Significance of Computed Tomography and Serum Potassium in Predicting Subtype Diagnosis of Primary Aldosteronism by Umakoshi, Hironobu, Tsuiki, Mika, Takeda, Yoshiyu, Kurihara, Isao, Itoh, Hiroshi, Katabami, Takuyuki, Ichijo, Takamasa, Wada, Norio, Yoshimoto, Takanobu, Ogawa, Yoshihiro, Kawashima, Junji, Sone, Masakatsu, Inagaki, Nobuya, Takahashi, Katsutoshi, Watanabe, Minemori, Matsuda, Yuichi, Kobayashi, Hiroki, Shibata, Hirotaka, Kamemura, Kohei, Otsuki, Michio, Fujii, Yuichi, Yamamto, Koichi, Ogo, Atsushi, Yanase, Toshihiko, Suzuki, Tomoko, Naruse, Mitsuhide

“…The number of centers with established adrenal venous sampling (AVS) programs for the subtype diagnosis of primary aldosteronism (PA) is limited. Aim was to…”
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Sodium-glucose cotransporter 2 inhibitor canagliflozin attenuates lung cancer cell proliferation in vitro by Yamamoto, Leona, Yamashita, Shinichi, Nomiyama, Takashi, Kawanami, Takako, Hamaguchi, Yuriko, Shigeoka, Toru, Horikawa, Tsuyoshi, Tanaka, Yuki, Yanase, Toshihiko, Kawanami, Daiji, Iwasaki, Akinori

“…Cancer is a major cause of death in patients with type 2 diabetes mellitus (T2DM) and lung cancer is one of the most prevalent cancers in patients with T2DM…”
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Perilipin 5, a Lipid Droplet-binding Protein, Protects Heart from Oxidative Burden by Sequestering Fatty Acid from Excessive Oxidation by Kuramoto, Kenta, Okamura, Tomoo, Yamaguchi, Tomohiro, Nakamura, Tomoe Y., Wakabayashi, Shigeo, Morinaga, Hidetaka, Nomura, Masatoshi, Yanase, Toshihiko, Otsu, Kinya, Usuda, Nobuteru, Matsumura, Shigenobu, Inoue, Kazuo, Fushiki, Tohru, Kojima, Yumiko, Hashimoto, Takeshi, Sakai, Fumie, Hirose, Fumiko, Osumi, Takashi

“…Lipid droplets (LDs) are ubiquitous organelles storing neutral lipids, including triacylglycerol (TAG) and cholesterol ester. The properties of LDs vary…”
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Exendin-4, a GLP-1 receptor agonist, attenuates prostate cancer growth by Nomiyama, Takashi, Kawanami, Takako, Irie, Shinichiro, Hamaguchi, Yuriko, Terawaki, Yuichi, Murase, Kunitaka, Tsutsumi, Yoko, Nagaishi, Ryoko, Tanabe, Makito, Morinaga, Hidetaka, Tanaka, Tomoko, Mizoguchi, Makio, Nabeshima, Kazuki, Tanaka, Masatoshi, Yanase, Toshihiko

“…Recently, pleiotropic benefits of incretin therapy beyond glycemic control have been reported. Although cancer is one of the main causes of death in diabetic…”
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High sex hormone-binding globulin concentration is a risk factor for high fibrosis-4 index in middle-aged Japanese men by Fujihara, Yuya, Hamanoue, Nobuya, Yano, Hiromi, Tanabe, Makito, Akehi, Yuko, Nomiyama, Takashi, Yanase, Toshihiko

“…Low endogenous testosterone and sex hormone-binding globulin (SHBG) concentrations have been reported to be associated with metabolic syndrome (MetS) and…”
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Development of a simple prediction model for adrenal crisis diagnosis by Katabami, Takuyuki, Tsukiyama, Hidekazu, Tanabe, Makito, Matsuba, Ren, Murakami, Mariko, Nishine, Ami, Shimizu, Sachi, Sakai, Kensuke, Tanaka, Yasushi, Yanase, Toshihiko

“…To develop a prediction model for adrenal crisis (AC) diagnosis among individuals with adrenal insufficiency that relies on the values of routinely measured…”
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A simple questionnaire for the detection of testosterone deficiency in men with late-onset hypogonadism by Akehi, Yuko, Tanabe, Makito, Yano, Hiromi, Takashi, Yuichi, Kawanami, Daiji, Nomiyama, Takashi, Yanase, Toshihiko

“…The Aging Males’ Symptoms (AMS) score, developed to screen for late-onset hypogonadism (LOH), contains 17 questions regarding mental, physical, and sexual…”
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Diagnosis and treatment of adrenal insufficiency including adrenal crisis: a Japan Endocrine Society clinical practice guideline [Opinion] by Yanase, Toshihiko, Tajima, Toshihiro, Katabami, Takuyuki, Iwasaki, Yasumasa, Tanahashi, Yusuke, Sugawara, Akira, Hasegawa, Tomonobu, Mune, Tomoatsu, Oki, Yutaka, Nakagawa, Yuichi, Miyamura, Nobuhiro, Shimizu, Chikara, Otsuki, Michio, Nomura, Masatoshi, Akehi, Yuko, Tanabe, Makito, Kasayama, Soji

“…This clinical practice guideline of the diagnosis and treatment of adrenal insufficiency (AI) including adrenal crisis was produced on behalf of the Japan…”
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Prescription of oral hypoglycemic agents for patients with type 2 diabetes mellitus: A retrospective cohort study using a Japanese hospital database by Tanabe, Makito, Motonaga, Ryoko, Terawaki, Yuichi, Nomiyama, Takashi, Yanase, Toshihiko

“…Aims/Introduction In treatment algorithms of type 2 diabetes mellitus in Western countries, biguanides are recommended as first‐line agents. In Japan, various…”
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Impact of adrenocorticotropic hormone stimulation during adrenal venous sampling on outcomes of primary aldosteronism by Takeda, Yoshiyu, Umakoshi, Hironobu, Takeda, Yoshimichi, Yoneda, Takashi, Kurihara, Isao, Katabami, Takuyuki, Ichijo, Takamasa, Wada, Norio, Yoshimoto, Takanobu, Ogawa, Yoshihiro, Kawashima, Junji, Sone, Masakatsu, Takahashi, Katsutoshi, Watanabe, Minemori, Matsuda, Yuichi, Kobayashi, Hiroki, Shibata, Hirotaka, Kamemura, Kohei, Otsuki, Michio, Fujii, Yuichi, Yamamto, Koichi, Ogo, Atsushi, Yanase, Toshihiko, Suzuki, Tomoko, Naruse, Mitsuhide

“…BACKGROUND:Adrenal venous sampling (AVS) is essential for identifying a surgically curable form of primary aldosteronism. Adrenocorticotropic hormone (ACTH)…”
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Clinical Characteristics and Postoperative Outcomes of Primary Aldosteronism in the Elderly by Takeda, Masao, Yamamoto, Koichi, Akasaka, Hiroshi, Rakugi, Hiromi, Naruse, Mitsuhide, Takeda, Yoshiyu, Kurihara, Isao, Itoh, Hiroshi, Umakoshi, Hironobu, Tsuiki, Mika, Ichijo, Takamasa, Katabami, Takuyuki, Wada, Norio, Shibayama, Yui, Yoshimoto, Takanobu, Ogawa, Yoshihiro, Kawashima, Junji, Sone, Masakatsu, Inagaki, Nobuya, Takahashi, Katsutoshi, Fujita, Megumi, Watanabe, Minemori, Matsuda, Yuichi, Kobayashi, Hiroki, Shibata, Hirotaka, Kamemura, Kohei, Otsuki, Michio, Fujii, Yuichi, Ogo, Atsushi, Okamura, Shintaro, Miyauchi, Shozo, Yanase, Toshihiko, Suzuki, Tomoko, Kawamura, Takashi

“…Primary aldosteronism (PA) in the elderly has increased in importance in association with population aging. To investigate the characteristics and outcomes of…”
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