Search Results - "Tosello Boari, Jimena"

Tumor invasion in draining lymph nodes is associated with Treg accumulation in breast cancer patients by Núñez, Nicolas Gonzalo, Tosello Boari, Jimena, Ramos, Rodrigo Nalio, Richer, Wilfrid, Cagnard, Nicolas, Anderfuhren, Cyrill Dimitri, Niborski, Leticia Laura, Bigot, Jeremy, Meseure, Didier, De La Rochere, Philippe, Milder, Maud, Viel, Sophie, Loirat, Delphine, Pérol, Louis, Vincent-Salomon, Anne, Sastre-Garau, Xavier, Burkhard, Becher, Sedlik, Christine, Lantz, Olivier, Amigorena, Sebastian, Piaggio, Eliane

“…Tumor-draining lymph node (TDLN) invasion by metastatic cells in breast cancer correlates with poor prognosis and is associated with local immunosuppression,…”
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CD39 Expression Defines Cell Exhaustion in Tumor-Infiltrating CD8 + T Cells by Canale, Fernando P, Ramello, María C, Núñez, Nicolás, Araujo Furlan, Cintia L, Bossio, Sabrina N, Gorosito Serrán, Melisa, Tosello Boari, Jimena, Del Castillo, Andrés, Ledesma, Marta, Sedlik, Christine, Piaggio, Eliane, Gruppi, Adriana, Acosta Rodríguez, Eva A, Montes, Carolina L

“…The ability of CD8 T lymphocytes to eliminate tumors is limited by their ability to engender an immunosuppressive microenvironment. Here we describe a subset…”
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CD74 supports accumulation and function of regulatory T cells in tumors by Bonnin, Elisa, Rodrigo Riestra, Maria, Marziali, Federico, Mena Osuna, Rafael, Denizeau, Jordan, Maurin, Mathieu, Saez, Juan Jose, Jouve, Mabel, Bonté, Pierre-Emmanuel, Richer, Wilfrid, Nevo, Fabien, Lemoine, Sebastien, Girard, Nicolas, Lefevre, Marine, Borcoman, Edith, Vincent-Salomon, Anne, Baulande, Sylvain, Moreau, Helene D., Sedlik, Christine, Hivroz, Claire, Lennon-Duménil, Ana-Maria, Tosello Boari, Jimena, Piaggio, Eliane

“…Regulatory T cells (Tregs) are plastic cells playing a pivotal role in the maintenance of immune homeostasis. Tregs actively adapt to the microenvironment…”
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Galectin-3 deficiency drives lupus-like disease by promoting spontaneous germinal centers formation via IFN-γ by Beccaria, Cristian Gabriel, Amezcua Vesely, María Carolina, Fiocca Vernengo, Facundo, Gehrau, Ricardo Carlos, Ramello, María Cecilia, Tosello Boari, Jimena, Gorosito Serrán, Melisa, Mucci, Juan, Piaggio, Eliane, Campetella, Oscar, Acosta Rodríguez, Eva Virginia, Montes, Carolina Lucía, Gruppi, Adriana

“…Germinal centers (GC) are important sites for high-affinity and long-lived antibody induction. Tight regulation of GC responses is critical for maintaining…”
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IL‐1β/CD14 pathway induces IL‐17 production: Dendritic cells activated with IL‐1β set Th17 cells on fire by CD14‐mediated mechanisms by Tosello Boari, Jimena, Acosta Rodriguez, Eva V

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IL-17RA signaling reduces inflammation and mortality during Trypanosoma cruzi infection by recruiting suppressive IL-10-producing neutrophils by Tosello Boari, Jimena, Amezcua Vesely, María Carolina, Bermejo, Daniela Andrea, Ramello, Maria Cecilia, Montes, Carolina Lucía, Cejas, Hugo, Gruppi, Adriana, Acosta Rodríguez, Eva Virginia

“…Members of the IL-17 cytokine family play an important role in protection against pathogens through the induction of different effector mechanisms. We…”
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Interleukin-17 signaling influences CD8+ T cell immunity and tumor progression according to the IL-17 receptor subunit expression pattern in cancer cells by Rodriguez, Constanza, Araujo Furlan, Cintia L., Tosello Boari, Jimena, Bossio, Sabrina N., Boccardo, Santiago, Fozzatti, Laura, Canale, Fernando P., Beccaria, Cristian G., Nuñez, Nicolás G., Ceschin, Danilo G., Piaggio, Eliane, Gruppi, Adriana, Montes, Carolina L., Acosta Rodríguez, Eva V.

“…IL-17 immune responses in cancer are controversial, with both tumor-promoting and tumor-repressing effects observed. To clarify the role of IL-17 signaling in…”
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Inhibitory Receptor Expression on T Cells as a Marker of Disease Activity and Target to Regulate Effector Cellular Responses in Rheumatoid Arthritis by Onofrio, Luisina I., Zacca, Estefania R., Ferrero, Paola, Acosta, Cristina, Mussano, Eduardo, Onetti, Laura, Cadile, Isaac, Gazzoni, M. Victoria, Jurado, Raúl, Boari, Jimena Tosello, Ramello, Maria C., Montes, Carolina L., Gruppi, Adriana, Acosta Rodríguez, Eva V.

“…Objective Inhibitory receptors are essential for the regulation of effector immune responses and may play critical roles in autoimmune diseases. We evaluated…”
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CD39+ conventional CD4+ T cells with exhaustion traits and cytotoxic potential infiltrate tumors and expand upon CTLA-4 blockade by Bossio, Sabrina N., Abrate, Carolina, Tosello Boari, Jimena, Rodriguez, Constanza, Canale, Fernando P., Ramello, María C., Brunotto, Valentina, Richer, Wilfrid, Rocha, Dario, Sedlik, Christine, Vincent-Salomon, Anne, Borcoman, Edith, Del Castillo, Andres, Gruppi, Adriana, Fernandez, Elmer, Acosta Rodríguez, Eva V., Piaggio, Eliane, Montes, Carolina L.

“…Conventional CD4 + T (Tconv) lymphocytes play important roles in tumor immunity; however, their contribution to tumor elimination remains poorly understood…”
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CD8 + T Cell Immunity Is Compromised by Anti-CD20 Treatment and Rescued by Interleukin-17A by Fiocca Vernengo, Facundo, Beccaria, Cristian G, Araujo Furlan, Cintia L, Tosello Boari, Jimena, Almada, Laura, Gorosito Serrán, Melisa, Gazzoni, Yamila, Montes, Carolina L, Acosta Rodríguez, Eva V, Gruppi, Adriana

“…Treatment with anti-CD20, used in many diseases in which B cells play a pathogenic role, has been associated with susceptibility to intracellular infections…”
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IL-17RA-Signaling Modulates CD8+ T Cell Survival and Exhaustion During Trypanosoma cruzi Infection by Tosello Boari, Jimena, Araujo Furlan, Cintia L, Fiocca Vernengo, Facundo, Rodriguez, Constanza, Ramello, María C, Amezcua Vesely, María C, Gorosito Serrán, Melisa, Nuñez, Nicolás G, Richer, Wilfrid, Piaggio, Eliane, Montes, Carolina L, Gruppi, Adriana, Acosta Rodríguez, Eva V

“…The IL-17 family contributes to host defense against many intracellular pathogens by mechanisms that are not fully understood. CD8+ T lymphocytes are key…”
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Limited Foxp3 + Regulatory T Cells Response During Acute Trypanosoma cruzi Infection Is Required to Allow the Emergence of Robust Parasite-Specific CD8 + T Cell Immunity by Araujo Furlan, Cintia L, Tosello Boari, Jimena, Rodriguez, Constanza, Canale, Fernando P, Fiocca Vernengo, Facundo, Boccardo, Santiago, Beccaria, Cristian G, Adoue, Véronique, Joffre, Olivier, Gruppi, Adriana, Montes, Carolina L, Acosta Rodriguez, Eva V

“…While it is now acknowledged that CD4 T cells expressing CD25 and Foxp3 (Treg cells) regulate immune responses and, consequently, influence the pathogenesis of…”
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Unconventional Pro-inflammatory CD4 + T Cell Response in B Cell-Deficient Mice Infected with Trypanosoma cruzi by Gorosito Serrán, Melisa, Tosello Boari, Jimena, Fiocca Vernengo, Facundo, Beccaría, Cristian G, Ramello, María C, Bermejo, Daniela A, Cook, Amelia G, Vinuesa, Carola G, Montes, Carolina L, Acosta Rodriguez, Eva V, Gruppi, Adriana

“…Chagas disease, caused by the parasite , is endemic in Latin America but has become a global public health concern by migration of infected people. It has been…”
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Tissue-resident FOLR2+ macrophages associate with CD8+ T cell infiltration in human breast cancer by Nalio Ramos, Rodrigo, Missolo-Koussou, Yoann, Gerber-Ferder, Yohan, Bromley, Christian P., Bugatti, Mattia, Núñez, Nicolas Gonzalo, Tosello Boari, Jimena, Richer, Wilfrid, Menger, Laurie, Denizeau, Jordan, Sedlik, Christine, Caudana, Pamela, Kotsias, Fiorella, Niborski, Leticia L., Viel, Sophie, Bohec, Mylène, Lameiras, Sonia, Baulande, Sylvain, Lesage, Laëtitia, Nicolas, André, Meseure, Didier, Vincent-Salomon, Anne, Reyal, Fabien, Dutertre, Charles-Antoine, Ginhoux, Florent, Vimeux, Lene, Donnadieu, Emmanuel, Buttard, Bénédicte, Galon, Jérôme, Zelenay, Santiago, Vermi, William, Guermonprez, Pierre, Piaggio, Eliane, Helft, Julie

“…Macrophage infiltration is a hallmark of solid cancers, and overall macrophage infiltration correlates with lower patient survival and resistance to therapy…”
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Autoimmunity affecting the biliary tract fuels the immunosurveillance of cholangiocarcinoma by Paillet, Juliette, Plantureux, Céleste, Lévesque, Sarah, Le Naour, Julie, Stoll, Gautier, Sauvat, Allan, Caudana, Pamela, Tosello Boari, Jimena, Bloy, Norma, Lachkar, Sylvie, Martins, Isabelle, Opolon, Paule, Checcoli, Andrea, Delaune, Agathe, Robil, Noémie, de la Grange, Pierre, Hamroune, Juliette, Letourneur, Franck, Autret, Gwennhael, Leung, Patrick S C, Gershwin, M Eric, Zhu, Jie S, Kurth, Mark J, Lekbaby, Bouchra, Augustin, Jérémy, Kim, Youra, Gujar, Shashi, Coulouarn, Cédric, Fouassier, Laura, Zitvogel, Laurence, Piaggio, Eliane, Housset, Chantal, Soussan, Patrick, Maiuri, Maria Chiara, Kroemer, Guido, Pol, Jonathan G

“…Cholangiocarcinoma (CCA) results from the malignant transformation of cholangiocytes. Primary sclerosing cholangitis (PSC) and primary biliary cholangitis…”
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Polyfunctional KLRG-1 + CD57 + Senescent CD4 + T Cells Infiltrate Tumors and Are Expanded in Peripheral Blood From Breast Cancer Patients by Ramello, Maria C, Núñez, Nicolás G, Tosello Boari, Jimena, Bossio, Sabrina N, Canale, Fernando P, Abrate, Carolina, Ponce, Nicolas, Del Castillo, Andrés, Ledesma, Marta, Viel, Sophie, Richer, Wilfrid, Sedlik, Christine, Tiraboschi, Carolina, Muñoz, Marcos, Compagno, Daniel, Gruppi, Adriana, Acosta Rodríguez, Eva V, Piaggio, Eliane, Montes, Carolina L

“…Senescent T cells have been described during aging, chronic infections, and cancer; however, a comprehensive study of the phenotype, function, and…”
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Extrafollicular Plasmablasts Present in the Acute Phase of Infections Express High Levels of PD-L1 and Are Able to Limit T Cell Response by Serrán, Melisa Gorosito, Vernengo, Facundo Fiocca, Almada, Laura, Beccaria, Cristian G, Gazzoni, Yamila, Canete, Pablo F, Roco, Jonathan A, Boari, Jimena Tosello, Ramello, Maria Cecilia, Wehrens, Ellen, Cai, Yeping, Zuniga, Elina I, Montes, Carolina L, Cockburn, Ian A, Rodriguez, Eva V Acosta, Vinuesa, Carola G, Gruppi, Adriana

“…During infections with protozoan parasites or some viruses, T cell immunosuppression is generated simultaneously with a high B cell activation. It has been…”
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IL-1[beta]/CD14 pathway induces IL-17 production: Dendritic cells activated with IL-1[beta] set Th17 cells on fire by CD14-mediated mechanisms by Tosello Boari, Jimena, Acosta Rodriguez, Eva V

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Adoptive Transfer of Isolated Bone Marrow Neutrophils by Jimena Boari, Eva Rodríguez

“…Adoptive transfer experiments of specific cell populations are widely used methods to assess the role of the injected population on an ongoing process. In the…”
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